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TIMP3 antibody (Internal Region)

TIMP3 Reactivity: Human, Rat, Mouse WB, ELISA, IHC, IF, ICC Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN6265583
  • Target See all TIMP3 Antibodies
    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
    Binding Specificity
    • 15
    • 12
    • 8
    • 8
    • 7
    • 7
    • 7
    • 5
    • 5
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Internal Region
    Reactivity
    • 101
    • 51
    • 43
    • 22
    • 20
    • 19
    • 17
    • 8
    • 5
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    Human, Rat, Mouse
    Host
    • 98
    • 9
    • 3
    Rabbit
    Clonality
    • 100
    • 10
    Polyclonal
    Conjugate
    • 55
    • 11
    • 8
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This TIMP3 antibody is un-conjugated
    Application
    • 80
    • 45
    • 30
    • 25
    • 14
    • 13
    • 13
    • 11
    • 8
    • 7
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificity
    TIMP3 Antibody detects endogenous levels of total TIMP3.
    Predicted Reactivity
    Pig,Bovine,Horse,Sheep,Rabbit,Dog,Chicken,Xenopus
    Purification
    The antiserum was purified by peptide affinity chromatography using SulfoLinkTM Coupling Resin (Thermo Fisher Scientific).
    Immunogen
    A synthesized peptide derived from human TIMP3, corresponding to a region within the internal amino acids.
    Isotype
    IgG
  • Application Notes
    WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500, ELISA(peptide) 1:20000-1:40000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    Rabbit IgG in phosphate buffered saline , pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20 °C. Stable for 12 months from date of receipt.
    Expiry Date
    12 months
  • Mao, Du, Yang, Zhang, Peng, Jiang, Zhou: "Inhibitors of PARP-1 exert inhibitory effects on the biological characteristics of hepatocellular carcinoma cells in vitro." in: Molecular medicine reports, Vol. 16, Issue 1, pp. 208-214, (2018) (PubMed).

  • Target
    TIMP3 (TIMP Metallopeptidase Inhibitor 3 (TIMP3))
    Alternative Name
    TIMP3 (TIMP3 Products)
    Synonyms
    TIMP-3 antibody, TIMP3 antibody, timp3 antibody, HSMRK222 antibody, K222 antibody, K222TA2 antibody, SFD antibody, IMP-3 antibody, timp3-A antibody, Timp-3 antibody, metalloproteinase inhibitor 3 antibody, TIMP metallopeptidase inhibitor 3 antibody, Metalloproteinase inhibitor 3 antibody, TIMP metallopeptidase inhibitor 3 L homeolog antibody, tissue inhibitor of metalloproteinase 3 antibody, CpipJ_CPIJ003282 antibody, TIMP3 antibody, timp3 antibody, Timp3 antibody, timp3.L antibody
    Background

    Description: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

    Gene: TIMP3

    Molecular Weight
    24kDa
    Gene ID
    7078
    UniProt
    P35625
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