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anti-TP53 Apoptosis Effector (PERP) Antibodies

Component of intercellular desmosome junctions. Additionally we are shipping PERP Proteins (4) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PERP 64058 Q9JK95
PERP 64065 Q96FX8
PERP 292949  
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Top anti-PERP Antibodies at antibodies-online.com

Showing 10 out of 63 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PERP Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: PANC1 cell lysate WB Suggested Anti-PERP  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: PANC1 cell lysate  PERP is supported by BioGPS gene expression data to be expressed in PANC1 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated ELISA, WB ABIN185623 (1µg/ml) staining of human liver lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated IHC (p), WB PERP Antibody (C-term) (ABIN658429) western blot analysis in NCI-H292 cell line lysates (35 µg/lane). This demonstrates the PERP antibody detected the PERP protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Dog Goat Un-conjugated WB 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of PERP in A431 cells with this product at 10 μg/ml. Western blot analysis of PERP expression in A431 whole cell lysates in the absence (A) and presence (B) of blocking peptide with this product at 1 μg /ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Goat Un-conjugated ELISA, WB 0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with PERP antibody ABIN213966 at 5 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Un-conjugated IF, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details

PERP Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine)
,

Human ,
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, , , , ,
Rat (Rattus)


Top referenced anti-PERP Antibodies

  1. Human Polyclonal PERP Primary Antibody for EIA, IF - ABIN500475 : Matsuoka, Huang, Elledge: Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. in Science (New York, N.Y.) 1998 (PubMed)
    Show all 4 references for ABIN500475

  2. Human Polyclonal PERP Primary Antibody for ELISA, WB - ABIN185623 : Ihrie, Marques, Nguyen, Horner, Papazoglu, Bronson, Mills, Attardi: Perp is a p63-regulated gene essential for epithelial integrity. in Cell 2005 (PubMed)

  3. Human Polyclonal PERP Primary Antibody for WB - ABIN2783850 : Ihrie, Attardi: Perp-etrating p53-dependent apoptosis. in Cell cycle (Georgetown, Tex.) 2004 (PubMed)

  4. Human Polyclonal PERP Primary Antibody for IHC (p), WB - ABIN658429 : Bailey, Xie, Do, Montpetit, Diaz, Mohan, Keavney, Yusuf, Gerstein, Engert, Anand: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. in Diabetes Care 2010 (PubMed)

More Antibodies against PERP Interaction Partners

Zebrafish TP53 Apoptosis Effector (PERP) interaction partners

  1. In contrast to its proapoptotic function in stressed cells, Perp plays an antiapoptotic role during normal zebrafish development to regulate tissue-specific cell survival.

Mouse (Murine) TP53 Apoptosis Effector (PERP) interaction partners

  1. Perp might play important roles in the formation and integration of stellate reticulum, dental lamina structure and enamel formation

  2. an important role for Perp in normal mammary tissue function and in mammary cancer suppression

  3. Data show that PERP is necessary for the integrity of the ameloblast-SI interface and that a lack of Perp causes downregulation of genes that are required for proper enamel formation.

  4. Studies suggest that Perp-deficiency promotes cancer by enhancing cell surv (show CDH1 Antibodies)ival, desmosome loss, and inflammatio (show CYP11A1 Antibodies)n, and they highlight a fundamental role for Perp and desmosomes in tumor suppression.

  5. In contrast to p53 shRNAs, PUMA shRNAs were unable to cooperate with oncogenic ras in transformation

  6. Perp is a key effector in the p63 (show CKAP4 Antibodies) developmental program.

  7. Perp is required for efficient skin carcinogenesis and suggest a role for intact cell-cell adhesion in supporting tumor development in these settings.

  8. Perp is requered throughout adult life for proper epithelial homeostasis and function.

  9. PERP, a p53 (show TP53 Antibodies) proapoptotic target, mediates apoptotic cell death in renal ischemia.

  10. pemphigus vulgaris (show DSG3 Antibodies) autoantibodies disrupt Perp expression at the membrane and trigger its internalization along with DSG3 (show DSG3 Antibodies) into the endosomal pathway, where it is ultimately targeted to the lysosome for degradation

Human TP53 Apoptosis Effector (PERP) interaction partners

  1. The authors identified the tetraspanning membrane protein, p53 (show TP53 Antibodies) effector related to PMP-22 (show PMP22 Antibodies) (PERP), as a Salmonella typhimurium SipA binding partner.

  2. Decreased PERP expression on peripheral blood mononuclear cells from patient with rheumatoid arthritis negatively correlates with disease activity.

  3. Perp expression is reduced in human breast cancer cell lines

  4. PERP expression stabilizes active p53 (show TP53 Antibodies) via modulation of p53 (show TP53 Antibodies)-MDM2 (show MDM2 Antibodies) interaction in uveal melanoma cells.

  5. Data suggest a temporal sequence whereby PERP loss occurs before E-cadherin (show CDH1 Antibodies) loss in the progression of human SCC (show CYP11A1 Antibodies).

  6. findings underline the apoptotic pathway mediated by PERP as a critical mechanism employed by uveal melanoma tumours to modulate susceptibility to apoptosis

  7. pemphigus vulgaris (show DSG3 Antibodies) autoantibodies disrupt Perp expression at the membrane and trigger its internalization along with DSG3 (show DSG3 Antibodies) into the endosomal pathway, where it is ultimately targeted to the lysosome for degradation

  8. We demonstrate here that PERP induction is in fact compromised with some, but not all, Ankyloblepharon Ectodermal Dysplasia and Cleft Lip/Palate, AEC-patient derived TP63 (show TP63 Antibodies) mutants.

  9. A paper describing the identification of Perp (p53 Apoptosis Effector Related to PMP22). Perp was found as a novel target gene of the p53 tumor suppressor (show TP53 Antibodies), which is selectively induced during apoptosis compared to cell cycle arrest.

PERP Antigen Profile

Protein Summary

Component of intercellular desmosome junctions. Plays a role in stratified epithelial integrity and cell-cell adhesion by promoting desmosome assembly. Plays a role as an effector in the TP53-dependent apoptotic pathway (By similarity).

Gene names and symbols associated with PERP

  • TP53 apoptosis effector (LOC421682) antibody
  • PERP, TP53 apoptosis effector (PERP) antibody
  • PERP, TP53 apoptosis effector (perp) antibody
  • PERP, TP53 apoptosis effector (LOC100221212) antibody
  • PERP, TP53 apoptosis effector (Perp) antibody
  • 1110017A08Rik antibody
  • dJ496H19.1 antibody
  • fk24g11 antibody
  • KCP1 antibody
  • KRTCAP1 antibody
  • LOC100221212 antibody
  • PERP antibody
  • PERPL antibody
  • PIGPC1 antibody
  • RP3-496H19.1 antibody
  • THW antibody
  • wu:fk24g11 antibody

Protein level used designations for PERP

PERP, TP53 apoptosis effector , TP53 apoptosis effector , p53 apoptosis effector related to PMP-22 , rp3-496h19.1 , p53 apoptosis effector related to pmp-22 , KCP-1 , keratinocyte-associated protein 1 , p53 apoptosis effector related to Pmp22 , p53 apoptosis-associated target , 1110017A08Rik , keratinocytes associated protein 1 , p53 apoptosis effector related to PMP22 , p53-induced protein PIGPC1 , transmembrane protein THW

GENE ID SPECIES
421682 Gallus gallus
421683 Gallus gallus
444660 Xenopus laevis
494479 Danio rerio
548916 Xenopus (Silurana) tropicalis
703890 Macaca mulatta
100025866 Monodelphis domestica
100067837 Equus caballus
100221212 Taeniopygia guttata
100528358 Ictalurus punctatus
64058 Mus musculus
64065 Homo sapiens
476218 Canis lupus familiaris
292949 Rattus norvegicus
509485 Bos taurus
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