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Thiopurine S-Methyltransferase (TPMT) ELISA Kits

TPMT encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Additionally we are shipping TPMT Antibodies (111) and TPMT Proteins (33) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
TPMT 22017 O55060
TPMT 7172 P51580
TPMT 690050  
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Top TPMT ELISA Kits at antibodies-online.com

Showing 5 out of 13 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.127 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
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Mouse
  96 Tests Log in to see 11 to 13 Days
$1,029.60
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Cow
  96 Tests Log in to see 11 to 13 Days
$1,029.60
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Rat
  96 Tests Log in to see 11 to 13 Days
$1,029.60
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Dog
  96 Tests Log in to see 11 to 13 Days
$1,095.60
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More ELISA Kits for TPMT Interaction Partners

Mouse (Murine) Thiopurine S-Methyltransferase (TPMT) interaction partners

  1. With the significant mitigation of TPMT wild type-expressing cells to cisplatin cytotoxicity, findings demonstrate a drug-gene interaction between increased TPMT activity and decreased susceptibility to cisplatin-induced toxicity of inner ear cells.

  2. These findings support the notion that germline polymorphisms in Tpmt affect not only host tissue toxicity but also antitumor effectiveness.

  3. suggestion that differential mouse TPMT activity is due to variation in mRNA expression

Human Thiopurine S-Methyltransferase (TPMT) interaction partners

  1. Review/Meta-analysis: thiopurine S-methyltransferase testing for averting drug toxicity.

  2. A point mutation in the thiopurine S-methyltransferase gene that led to exon 5 deletion in the transcribed mRNA.

  3. The aims of this research were to investigate the association of TPMT phenotypes with MDR1 genotypes.

  4. The aim of the study was to investigate frequencies of TPMT and ITPA (show ITPA ELISA Kits) polymorphisms in Lithuanian inflammatory bowel disease patients and analyze their association with azathioprine-related adverse events.

  5. With respect to TPMT, the variants TPMT*2 and TPMT*3A were not implicated in genetic susceptibility to childhood acute lymphoblastic leukemia

  6. structure-function relationships of TPMT

  7. The TPMT promoter region may serve as a pharmacogenomic biomarker when introducing thiopurine therapy

  8. The most frequently occurring nonfunctional TPMT allele in Croatian population is TPMT*3A. Variant genotypes were statistically significantly more common in Crohn's disease subgroup than in ulcerative colitis subgroup.

  9. Association of TPMT polymorphisms with overall azathioprine-induced adverse drug reactions, bone marrow toxicity and gastric intolerance, but not with hepatotoxicity (meta-analysis).

  10. association of TPMT polymorphisms with overall thiopurine-induced adverse drug reactions

TPMT Antigen Profile

Antigen Summary

This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals. A pseudogene for this locus is located on chromosome 18q.

Gene names and symbols associated with TPMT

  • thiopurine S-methyltransferase (tpmt) antibody
  • zgc:101684 (zgc:101684) antibody
  • thiopurine S-methyltransferase (tpm) antibody
  • thiopurine S-methyltransferase (MCA0794) antibody
  • thiopurine S-methyltransferase (Pnap_4948) antibody
  • thiopurine S-methyltransferase (Hhal_1383) antibody
  • thiopurine S-methyltransferase (TK90_1044) antibody
  • thiopurine S-methyltransferase (Slit_1144) antibody
  • thiopurine S-methyltransferase (Tint_0842) antibody
  • Thiopurine S-methyltransferase (Fbal_3334) antibody
  • thiopurine S-methyltransferase (Celly_3188) antibody
  • thiopurine S-methyltransferase (Weevi_1737) antibody
  • Thiopurine S-methyltransferase (Psefu_2696) antibody
  • Thiopurine S-methyltransferase (Metme_3860) antibody
  • thiopurine methyltransferase (Tpmt) antibody
  • thiopurine S-methyltransferase (TPMT) antibody
  • thiopurine S-methyltransferase (Tpmt) antibody
  • AW106912 antibody
  • MGC84277 antibody
  • NHLRC1 antibody

Protein level used designations for TPMT

thiopurine S-methyltransferase , Thiopurine S-methyltransferase , S-adenosyl-L-methionine:thiopurine S-methyltransferase , thiopurine methyltransferase , NHL repeat containing 1

GENE ID SPECIES
447769 Xenopus laevis
573111 Danio rerio
1168449 Shewanella oneidensis MR-1
3104309 Methylococcus capsulatus str. Bath
4685796 Polaromonas naphthalenivorans CJ2
4711327 Halorhodospira halophila SL1
8806802 Thioalkalivibrio sp. K90mix
8891817 Sideroxydans lithotrophicus ES-1
9151573 Thiomonas intermedia K12
9772187 Ferrimonas balearica DSM 9799
10265228 Cellulophaga lytica DSM 7489
10282995 Weeksella virosa DSM 16922
10657285 Pseudomonas fulva 12-X
10673875 Methylomonas methanica MC09
22017 Mus musculus
7172 Homo sapiens
403536 Canis lupus familiaris
511644 Bos taurus
690050 Rattus norvegicus
493759 Felis catus
100034066 Equus caballus
100009411 Oryctolagus cuniculus
471863 Pan troglodytes
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