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The protein encoded by TFB1M is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. Additionally we are shipping TFB1M Proteins (12) and TFB1M Kits (3) and many more products for this protein.
Showing 10 out of 43 products:
Human Polyclonal TFB1M Primary Antibody for ELISA, WB - ABIN4358618
Sánchez-Ferrero, Coto, Blázquez, Ribacoba, Guisasola, Salvador, Alvarez: Mutational screening of the mitochondrial transcription factors B1 and B2 (TFB1M and TFB2M) in Parkinson's disease. in Parkinsonism & related disorders 2009
Loss of TFB1M results in mitochondrial dysfunction that leads to impaired insulin (show INS Antibodies) secretion and diabetes.
Deficiency in TFB1M and impaired mitochondrial function contribute to the pathogenesis of type 2 diabetes.
The mRNA levels of TFB1M and TFB2M (show TFB2M Antibodies) are influenced by endurance training
Human mitochondrial transcription factor B1 methylates ribosomal RNA at a conserved stem-loop
TFB1 (show GTF2H1 Antibodies) interacts with the C-terminal activation region of h-mtTFA (show TFAM Antibodies) and stimulates transcription independently of its RNA methyltransferase activity
TFB1M is a nuclear-encoded modifier gene for phenotypic expression of the deafness-associated homoplasmic A1555G mutation in the mitochondrial 12S rRNA gene.
Distinct, but possibly coordinated functions of mtTFB1 and mtTFB2 (show TFB2M Antibodies) in mitochondrial gene expression and biogenesis.
This study suggested that DNA variants in TFB1M did not contribute to the risk for parkinson disease.
determined the variation in the TFAM (show TFAM Antibodies), TFB1M, and TFB2M (show TFB2M Antibodies) genes in cardiac hypertrophy
rRNA methyltransferase activity is necessary for induction of mitochondrial biogenesis by TFB1M, but not TFB2M (show TFB2M Antibodies).
Lethal haplotype 5 (HH5 (show CHD7 Antibodies)) is caused by a deletion of 138kbp, spanning position 93,233kb to 93,371kb on chromosome 9 (BTA9), harboring only dimethyl-adenosine transferase 1 (TFB1M).
The protein encoded by this gene is a dimethyltransferase that methylates the conserved stem loop of mitochondrial 12S rRNA. The encoded protein also is part of the basal mitochondrial transcription complex and is necessary for mitochondrial gene expression. The methylation and transcriptional activities of this protein are independent of one another. Variations in this gene may influence the severity of aminoglycoside-induced deafness (AID).
S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase 1
, dimethyladenosine transferase 1, mitochondrial
, homolog of yeast mitochondrial transcription factor B
, mitochondrial 12S rRNA dimethylase 1
, mitochondrial dimethyladenosine transferase 1
, mitochondrial transcription factor B1
, transcription factor B1, mitochondrial
, Mitochondrial dimethyladenosine transferase 1, mitochondrial
, dimethyladenosine transferase 1, mitochondrial-like
, mitochondrial translation factor B1