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Transient Receptor Potential Cation Channel, Subfamily C, Member 5 Proteins (TRPC5)

TRPC5 belongs to the transient receptor family. Additionally we are shipping Transient Receptor Potential Cation Channel, Subfamily C, Member 5 Antibodies (85) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRPC5 7224 Q9UL62
TRPC5 22067 Q9QX29
Rat TRPC5 TRPC5 140933  
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Top Transient Receptor Potential Cation Channel, Subfamily C, Member 5 Proteins at antibodies-online.com

Showing 5 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
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Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
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HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

TRPC5 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,
Mouse (Murine) ,
,

More Proteins for Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) Interaction Partners

Zebrafish Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. findings reveal a novel signalling pathway involved in development of the semicircular canal system, and suggest a previously unrecognized role for NCS-1 (show NCS1 Proteins) in mitochondrial function via its association with several mitochondrial proteins.

Pig (Porcine) Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. Data found that the pig adrenal medulla expressed predominantly TRPC1 (show TRPC1 Proteins), TRPC5, and TRPC6 (show TRPC6 Proteins) transcripts. The expression level of these TRPCs was significantly elevated in the adrenal medulla from pigs with metabolic syndrome.

Human Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. TrpC5 plays an important role in VEGF-mediated tumor angiogenesis, suggesting its potential clinical value for anti-angiogenesis therapy

  2. TRPC5 mRNA and protein levels were up-regulated in focal cortical dysplasia cortical lesions.

  3. Suppressing TrpC5 expression decreased nuclear beta-catenin (show CTNNB1 Proteins) accumulation, reduced the induction of ABCB1 (show ABCB1 Proteins), and reversed 5-fluorouracil neoplastic resistance.

  4. these results suggest that hypoosmotic cell-swelling activates Gq-coupled receptors, which in turn enhance the activation of TRPC5 by regulating this channel membrane trafficking

  5. Clemizole exhibits a sixfold selectivity for TRPC5.

  6. Riluzole can activate TRPC5 heterologously expressed in HEK293 cells as well as those endogenously expressed in the U-87 glioblastoma cell line.

  7. TrpC5-containing circulating extracellular vesicles may transfer chemoresistance.

  8. Microvesicles from tumor cells transferred TrpC5 to endothelial cells, inducing the expression of P-glycoprotein by activation of the transcription factor NFATc3 (show NFATC3 Proteins) (nuclear factor of activated T cells isoform c3).

  9. the S4-S5 linker is a critical constituent of TRPC4 (show TRPC4 Proteins)/C5 channel gating and that disturbance of its sequence allows channel opening independent of any sensor domain.

  10. Data using recombinant proteins expressed in vascular endothelial cells suggest that SigmaR1 (sigma 1-type opioid receptor (show SIGMAR1 Proteins)) is not involved in regulation of calcium signaling via TRPC5/TRPM3 (show TRPM3 Proteins) (transient receptor potential cation channels C5/M3).

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. the antidepressant and anxiolytic-like effects of a newly identified TRPC4 (show TRPC4 Proteins)/C5 inhibitor, M084.

  2. Riluzole can activate TRPC5 heterologously expressed in HEK293 cells as well as those endogenously expressed in the U-87 glioblastoma cell line.

  3. Loss or inhibition of TRPC5 abrogates podocyte cytoskeletal remodeling, prevents Rac1 activation, & stabilizes synaptopodin (show SYNPO Proteins). Genetic deletion or pharmacologic inhibition of TRPC5 protected mice from albuminuria.

  4. the S4-S5 linker is a critical constituent of TRPC4 (show TRPC4 Proteins)/C5 channel gating and that disturbance of its sequence allows channel opening independent of any sensor domain.

  5. Is unaltered in TRPC5 KO mice, but is abolished in TRPC1 (show TRPC1 Proteins) KO and TRPC1 (show TRPC1 Proteins)/4 DKO mice.

  6. NEB cells selectively expressed the Ca(2 (show CA2 Proteins)+)-permeable osmo- and mechanosensitive TRPC5 in their apical membranes, whereas immunoreactivity for TRP (show TYRP1 Proteins) vanilloid-4 and TRP (show TYRP1 Proteins) melastatin (show TRPM1 Proteins)-3 was abundant in virtually all other airway epithelial cells

  7. TRPC5 acts downstream of semaphorin signaling to cause changes in neuronal growth cone morphology and nervous system development.

  8. Agents that deplete intracellular Ca(2 (show CA2 Proteins)+) stores activate native heteromeric TRPC1 (show TRPC1 Proteins)/C5 channels in vascular smooth muscle cells.

  9. a novel function for TRPC5 that couples calcium signaling to a ubiquitin ligase pathway at the centrosome and thereby orchestrates dendrite patterning and connectivity in the brain

  10. findings demonstrate that highly cold-sensitive TRPC5 channels are a molecular component for detection and regional adaptation to cold temperatures in the peripheral nervous system that is distinct from noxious cold sensing

Cow (Bovine) Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) interaction partners

  1. Nitrix oxide can negatively modulate endogenous TRPC5-containing channels through an indirect mechanism.

  2. analysis of a TRPC6 (show TRPC6 Proteins)-TRPC5 channel cascade that restricts endothelial cell movement

Transient Receptor Potential Cation Channel, Subfamily C, Member 5 (TRPC5) Protein Profile

Protein Summary

This gene belongs to the transient receptor family. It encodes one of the seven mammalian TRPC (transient receptor potential channel) proteins. The encoded protein is a multi-pass membrane protein and is thought to form a receptor-activated non-selective calcium permeant cation channel. The protein is active alone or as a heteromultimeric assembly with TRPC1, TRPC3, and TRPC4. It also interacts with multiple proteins including calmodulin, CABP1, enkurin, Na(+)-H+ exchange regulatory factor (NHERF ), interferon-induced GTP-binding protein (MX1), ring finger protein 24 (RNF24), and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1).

Gene names and symbols associated with TRPC5

  • transient receptor potential cation channel, subfamily C, member 5a (trpc5a)
  • transient receptor potential cation channel, subfamily C, member 5 (TRPC5)
  • capacitative calcium entry channel 2 (TRP5)
  • transient receptor potential cation channel, subfamily C, member 5 (Trpc5)
  • CCE2 protein
  • trp protein
  • TRP-5 protein
  • TRP5 protein
  • Trpc5 protein
  • Trrp5 protein
  • wu:fi73f08 protein

Protein level used designations for TRPC5

transient receptor potential cation channel, subfamily C, member 5 , transient receptor potential channel subfamily C member 5 , CCE2 , rtrp5 , short transient receptor potential channel 5 , TRP-5 , hTRP5 , transient receptor potential channel 5 , transient receptor protein 5 , capacitative calcium entry channel 2 , mtrp5 , trp-related protein 5 , vtransient receptor potential cation channel, subfamily C, member 5

GENE ID SPECIES
557456 Danio rerio
422337 Gallus gallus
492072 Canis lupus familiaris
100037962 Sus scrofa
100009574 Oryctolagus cuniculus
7224 Homo sapiens
22067 Mus musculus
140933 Rattus norvegicus
407103 Bos taurus
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