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Transient Receptor Potential Cation Channel, Subfamily V, Member 1 Proteins (TRPV1)

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. Additionally we are shipping TRPV1 Antibodies (148) and TRPV1 Kits (26) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat TRPV1 TRPV1 83810 O35433
TRPV1 7442 Q8NER1
TRPV1 193034 Q704Y3
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Top TRPV1 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 11 to 13 Days
$823.90
Details

TRPV1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine) ,
,

More Proteins for Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) Interaction Partners

Zebrafish Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) interaction partners

  1. Results demonstrate that cell motility and Ca(2 (show CA2 Proteins)+)i activity are affected by pharmacological agents that target TRPV1, indicating a novel role for this channel during cell migration.

  2. Using knock-down studies, we also show that TRPV1 is required for normal heat-induced locomotion.

Human Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) interaction partners

  1. TRPV1 overexpression attenuates isoproterenolinduced myocardial fibrosis.

  2. Up regulation of TRPV1 mRNA associated with the esophageal reflux symptoms.

  3. Our results indicate that TRPV1 channel inhibitors show radiosensitizing action in cancer cells through inhibition of early DNA damage response

  4. Temperature sensors in TRPV1 activate in two steps to favor opening, and that the binding of sodium to an extracellular site exerts allosteric control over temperature-sensor activation and opening of the pore.

  5. The impaired Ca2 (show CA2 Proteins)+ homeostasis found in preeclampsia may correlate with the reduced TRPV-1 expression in preeclamptic placentas.

  6. a high concentration of calcium in seawater exacerbated lung injury, and TRPV1 channels were notable mediators of the calcium increase initiated by the seawater challenge.

  7. TRPV1 channel modulation by hyaluronan reduces pain.

  8. Results suggest that non-neuronal TRPV1 may contribute to acute pain in herpes zoster.

  9. Cellular physiology and molecular biology methods show that the TRPV1 pain receptor is another pharmacologic target of aspirin.

  10. The effects of specific agents on TRPV1 and TRPM8 (show TRPM8 Proteins) channels are intricately interrelated.

Mouse (Murine) Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) interaction partners

  1. TRPV1 play a role in airway inflammation in asthmatic mice.

  2. Our results indicate that TRPV1 channel inhibitors show radiosensitizing action in cancer cells through inhibition of early DNA damage response

  3. Electroacupuncture at ST25 was found to inhibit jejunal motility in an intensity-dependent manner, via a mechanism in which sympathetic nerves and TRPV1 receptors play an important role.

  4. These findings indicate that tongue heat sensitivity and hypersensitivity are dependent on the expression of transient receptor potential vanilloid 1 which is regulated via MeCP2 (show MECP2 Proteins) signaling in trigeminal ganglion neurons innervating the tongue.

  5. The behavioral and molecular data indicated that TRPV1 is strongly modulated by Cdk5 (show CDK5 Proteins)-mediated phosphorylation at position threonine-407(mouse)/threonine406(rat).

  6. Data show that in transient receptor potential vanilloid 1 (TRPV1) knockout allergic rhinitis (AR) mice, eosinophil infiltration, Th2/Th17 cytokines in the nasal mucosa, and IgE levels in serum decreased, compared with wild-type AR mice.

  7. This study suggests that targeting TRPV1 is beneficial in controlling body weight and TRPV1-associated mechanisms in mice.

  8. The TRPV1-mediated amendment of mitochondrial dysfunction may represent a novel target for management of early cardiac dysfunction.

  9. Trpv1 is involved in the ocular itch response in allergic conjunctivitis.

  10. TRPV4 (show TRPV4 Proteins)-mediated nociceptive information from the peripheral tissue excluding the spinal pathway might be involved the formalin behavioral response during phase I. Only TRPV1 might regulate the formalin behavioral response in peripheral neuron.

Rabbit Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) interaction partners

  1. This study is the first to shed light on the structural determinants required for the interaction between TRPV1 and evodiamine, and gives new suggestions for the rational design of novel TRPV1 ligands.

  2. TRPV1 is expressed in cells that are particularly active in Ca(2 (show CA2 Proteins)) exchange as well as in cells with significant water transport activity in eyes of New Zealand White rabbits and humans

  3. There is no correlation of expression of thromboxane A2 receptor with TRPV1 in dorsal root ganglia and nodose ganglia.

  4. HCl-induced activation of TRPV1 causes ATP release from esophageal epithelial cells that causes release of CGRP (show CALCA Proteins) and SP from esophageal submucosal neurons.

  5. Capsaicin increased secretion and upregulated the expression of TRPV1 and AQP5 (show AQP5 Proteins) in transplanted submandibular glands.

Guinea Pig Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1) interaction partners

  1. The contractile effect of anandamide in the guinea-pig small intestine is mediated by prostanoids but not TRPV1 receptors or capsaicin-sensitive nerves.

  2. Allergic airway inflammation can induce the expression of TRPV1 in tracheal A-fiber neurons.

TRPV1 Protein Profile

Protein Summary

Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene.

Gene names and symbols associated with TRPV1

  • transient receptor potential cation channel, subfamily V, member 1 (trpv1)
  • transient receptor potential cation channel, subfamily V, member 1 (Trpv1)
  • transient receptor potential cation channel, subfamily V, member 1 (TRPV1)
  • OTRPC1 protein
  • si:dkey-9e15.2 protein
  • TRPV1alpha protein
  • TRPV1beta protein
  • VR-1 protein
  • VR.5'sv protein
  • VR1 protein
  • Vr1l1 protein

Protein level used designations for TRPV1

TRPV1/2 , OTRPC1 , capsaicin receptor , osm-9-like TRP channel 1 , transient receptor potential cation channel subfamily V member 1 , vanilloid receptor 1 , vanilloid receptor subtype 1 , vanilloid receptor type 1 like protein 1 , vanilloid type 1 receptor , transient receptor potential vanilloid 1a , transient receptor potential vanilloid 1b , cation channel , transient receptor potential cation channel V1 , transient receptor potential vanilloid type 1 , transient receptor potential V1 , vanilloid receptor-like protein

GENE ID SPECIES
561195 Danio rerio
83810 Rattus norvegicus
7442 Homo sapiens
193034 Mus musculus
100008926 Oryctolagus cuniculus
445457 Canis lupus familiaris
100135466 Cavia porcellus
100038021 Sus scrofa
539074 Bos taurus
395259 Gallus gallus
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