TRPV1 Protein
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- Target See all TRPV1 Proteins
- TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))
- Protein Type
- Synthetic
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Origin
- Human
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Source
- HEK-293 Cells
- Purpose
- Human TRPV1 full length protein-synthetic nanodisc
- Characteristics
- Full Length Transmembrane Proteins (synthetic Nanodisc)
- Top Product
- Discover our top product TRPV1 Protein
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- Application Notes
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- Applications for VLPs:
- ELISA
- SPR affinity analysis
- Phage display screening
- Immunization
- Cell based assays
- CAR-T cell screening
- Protein cystal structure analysis
- Comment
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Synthetic Nanodisc can be prepared directly from the cells. The polymers used during this process have a dual function. It dissolves the cell membranes, like the detergent, and uses cellular phospholipids to form Nanodisc around the membrane proteins. The target protein embedded Nanodiscs can then be purified.
- Restrictions
- For Research Use only
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- Format
- Liquid
- Buffer
- Supplied in nanodisc solubilization buffer (20 mM Tris-HCl, 150 mM NaCl, pH 8.0)
- Storage
- -20 °C,-80 °C
- Storage Comment
- Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
- Expiry Date
- 12 months
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- Target
- TRPV1 (Transient Receptor Potential Cation Channel, Subfamily V, Member 1 (TRPV1))
- Alternative Name
- TRPV1 (TRPV1 Products)
- Synonyms
- si:dkey-9e15.2 Protein, VR.5'sv Protein, Vr1 Protein, Vr1l1 Protein, VR1 Protein, OTRPC1 Protein, TRPV1alpha Protein, TRPV1beta Protein, VR-1 Protein, transient receptor potential cation channel, subfamily V, member 1 Protein, transient receptor potential cation channel subfamily V member 1 Protein, trpv1 Protein, Trpv1 Protein, TRPV1 Protein
- Background
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VR1
Description: Capsaicin, the main pungent ingredient in hot chili peppers, elicits a sensation of burning pain by selectively activating sensory neurons that convey information about noxious stimuli to the central nervous system. The protein encoded by this gene is a receptor for capsaicin and is a non-selective cation channel that is structurally related to members of the TRP family of ion channels. This receptor is also activated by increases in temperature in the noxious range, suggesting that it functions as a transducer of painful thermal stimuli in vivo. Four transcript variants encoding the same protein, but with different 5' UTR sequence, have been described for this gene. [provided by RefSeq, Jul 2008] - Molecular Weight
- The human full length TRPV1 protein has a MW of 94.8 kDa
- UniProt
- Q8NER1
- Pathways
- Dicarboxylic Acid Transport
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