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Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.. Additionally we are shipping and many more products for this protein.
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Human Polyclonal TMBIM1 Primary Antibody for ELISA, WB - ABIN233805
Shukla, Fujita, Xiao, Liao, Garfield, Srinivasula: A shear stress responsive gene product PP1201 protects against Fas-mediated apoptosis by reducing Fas expression on the cell surface. in Apoptosis : an international journal on programmed cell death 2010
The combined analysis identified a new risk association for colorectal cancer (CRC (show CALR Antibodies)) at 2q35 marked by rs992157 which is intronic to PNKD (show PNKD Antibodies) and TMBIM1.Intriguingly this susceptibility single-nucleotide polymorphism (SNP) is in strong linkage disequilibrium (r(2) = 0.90, D' = 0.96) with the previously discovered GWAS SNP rs2382817 for inflammatory bowel disease (IBD).
TMBIM1 is an effective suppressor of steatohepatitis and a previously unknown regulator of the multivesicular body (MVB)-lysosomal pathway.
These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2 (show CA2 Antibodies)) homeostasis in a wide variety of tissues
data suggest that PP1201 functions as an anti-apoptotic protein and its increased expression in vascular cells can contribute to homeostasis by reducing Fas (show FAS Antibodies) trafficking to the cell membrane
The tmbim1 may participate in cell death regulation by interacting with proteins of Bcl-2 (show BCL2 Antibodies) family, promoting tumor metastasis, which is deduced from the evolutionary conservation of the membrane protein family containing multiple membrane spanning segments
TMBIM1 is an effective suppressor of steatohepatitis and a previously unknown regulator of the multivesicular body (MVB)-lysosomal pathway. Tmbim1 expression in hepatocytes substantially inhibited high-fat diet-induced insulin (show INS Antibodies) resistance, hepatic steatosis and inflammation in mice. Overexpression of Tmbim1 in the liver effectively inhibited a severe form of NAFLD (show TSC2 Antibodies) in mice.
RECS1 negatively regulates aortic MMP-9 (show MMP9 Antibodies) production and knocking out RECS1 induces susceptibility to aortic dilation as well as cystic medial degeneration in the aged mice.
Negatively regulates aortic matrix metalloproteinase-9 (MMP9) production and may play a protective role in vascular remodeling.
transmembrane BAX inhibitor motif-containing protein 1
, responsive to centrifugal force and shear
, transmembrane BAX inhibitor motif containing 1
, bax inhibitor-1
, Bax inhibitor-1
, protein lifeguard 3
, responsive to centrifugal force and shear stress gene 1 protein