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Triadin Proteins (TRDN)

TRDN encodes an integral membrane protein that contains a single transmembrane domain. Additionally we are shipping Triadin Antibodies (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRDN 76757  
Rat TRDN TRDN 59299  
TRDN 10345 Q13061
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Top Triadin Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 59 to 64 Days
$6,052.17
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 59 to 64 Days
$8,623.45
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Rabbit Un-conjugated   50 μg Log in to see 3 to 4 Days
$310.00
Details

TRDN Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , ,
, ,

More Proteins for Triadin (TRDN) Interaction Partners

Rabbit Triadin (TRDN) interaction partners

  1. These data for the first time demonstrate that Trisk 95's 200-231 region is responsible for ryanodine receptor activation.

Mouse (Murine) Triadin (TRDN) interaction partners

  1. Three regions in triadin are identified that mediate targeting to the junctional domain of sarcoplasmic reticulum.

  2. in skeletal muscle the disruption of Tdn/CASQ (show CASQ1 Proteins) link has a more profound effect on jSR architecture and myoplasmic Ca(2 (show CA2 Proteins)+) regulation than Jct/CASQ (show CASQ1 Proteins) association.

  3. The triadin-to-calsequestrin ratio is a critical modulator of the sarcoplasmic reticulum Ca(2 (show CA2 Proteins)+) signaling in ventricular myocytes.

  4. Ablation of skeletal muscle triadin impairs FKBP12 (show FKBP1A Proteins)/RyR1 channel interactions essential for maintaining resting cytoplasmic Ca2 (show CA2 Proteins)+.

  5. caveolin 3 (show CAV3 Proteins)-containing membrane domains and the calcium release complex are functionally linked and Trdn is instrumental to the regulation of this interaction, the integrity of which may be crucial for muscle physiology.

  6. Results demonstrate a reduction in muscle strength in triadin knockout mice, indicating that triadin plays an essential role in skeletal muscle function and in skeletal muscle structure.

  7. triadin 1 overexpression triggered time-dependent alterations in SR protein (show RNPS1 Proteins) expression, Ca(2 (show CA2 Proteins)+) homeostasis, and contractility, indicating for the first time an inhibitory function of triadin 1 on SR-Ca(2 (show CA2 Proteins)+) release in vivo.

  8. Triadin(TRD)xjunctin(JCN) mice were studied to compensate the down-regulation of junctin (show ASPH Proteins) expression in triadin-expressing mice; exercise or stress provoked repetitive ventricular tachycardia in freely roaming TRDxJCN mice.

  9. Histidine-rich Ca-binding protein may play a key role in the regulation of SR Ca cycling through its direct interactions with SERCA2 (show ATP2A2 Proteins) and triadin, mediating a fine cross talk between SR Ca uptake and release in the heart.

  10. triadin has a role in regulating myoplasmic Ca(2 (show CA2 Proteins)+) homeostasis and organizing the molecular complex of the triad but not in regulating skeletal-type excitation-contraction coupling

Human Triadin (TRDN) interaction partners

  1. We describe a new family with cathecholaminergic polymorphic ventricular tachycardia (CPVT) linked to the Triadin gene.

  2. Common variants in TRDN and CALM1 (show CALM1 Proteins) are associated with increased risk of sudden cardiac death in patients with chronic heart failure.

  3. TRDN is a novel underlying genetic basis for recessively inherited Long-QT syndrome.

  4. Data show that triadin (TRDN) is a new gene responsible for an autosomal recessive form of ctecholaminergic polymorphic ventricular tachycardia (CPVT).

  5. The researchers found evidence that TRDN may be a susceptibility or marker gene for IgA nephropathy

  6. Histidine-rich Ca-binding protein may play a key role in the regulation of SR Ca cycling through its direct interactions with SERCA2 (show ATP2A2 Proteins) and triadin, mediating a fine cross talk between SR Ca uptake and release in the heart.

  7. proteasome inhibition led to an accumulation of two new modified forms of triadin-1 that were seen with triadin-1 only when it is not glycosylated on Asn(75).

Triadin (TRDN) Protein Profile

Protein Summary

This gene encodes an integral membrane protein that contains a single transmembrane domain. As similar protein in rabbits plays a role in skeletal muscle excitation-contraction coupling as part of the calcium release complex in association with the ryanodine receptor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and single nucleotide polymorphisms in this gene may be markers for IgA nephritis.

Gene names and symbols associated with Triadin Proteins (TRDN)

  • triadin (TRDN)
  • triadin (EDI_200780)
  • triadin (AOR_1_2668174)
  • triadin (trdn)
  • Triadin (trdn)
  • triadin (Trdn)
  • 2310045H21Rik protein
  • DKFZp468F1917 protein
  • EG432451 protein
  • MGC140240 protein
  • si:dkey-72g4.2 protein
  • TDN protein
  • trdn protein
  • TRISK protein
  • zgc:162523 protein

Protein level used designations for Triadin Proteins (TRDN)

triadin , Triadin , junctional sarcoplasmic reticulum glycoprotein , cardiac triadin , triadin 1 , triadin 32 kDa (TRISK 32) , triadin 49 kDa (TRISK 49) , triadin 95

GENE ID SPECIES
100072982 Equus caballus
5882240 Entamoeba dispar SAW760
421721 Gallus gallus
534061 Bos taurus
744745 Pan troglodytes
5990393 Aspergillus oryzae RIB40
100038781 Danio rerio
100174478 Pongo abelii
100195662 Salmo salar
100584097 Nomascus leucogenys
100009519 Oryctolagus cuniculus
76757 Mus musculus
59299 Rattus norvegicus
10345 Homo sapiens
403776 Canis lupus familiaris
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