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The protein encoded by TRIM2 is a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM2 Antibodies (76) and TRIM2 Kits (1) and many more products for this protein.
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TRIM2 homozygous missense mutation (c.2000A>C; p.D667A) in a patient with peripheral neuropathy and bilateral vocal cord paralysis
The functional role of the C-terminal NHL domain was characterized in TRIM2.
TRIM2 is repressed by miR (show MLXIP Proteins)-9 and -181c, either alone or in combination.
a role for TRIM2 in mediating the p42/p44 (show PSMC6 Proteins) MAPK (show MAPK3 Proteins)-dependent ubiquitination of Bim (show BCL2L11 Proteins) in rapid ischemic tolerance.
Trim2 has an important function in the regulation of axon outgrowth during development.
TRIM2 is an ubiquitin ligase and point to a mechanism regulating neurofilament light subunit metabolism through an ubiquitination pathway that, if deregulated, triggers neurodegeneration
The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified.
E3 ubiquitin-protein ligase TRIM2
, RING finger protein 86
, tripartite motif protein 2
, tripartite motif protein TRIM2
, tripartite motif-containing 2
, tripartite motif-containing protein 2
, Tripartite motif-containing protein 2
, neural activity-related ring finger protein