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Tripartite Motif Containing 2 Proteins (TRIM2)

The protein encoded by TRIM2 is a member of the tripartite motif (TRIM) family. Additionally we are shipping TRIM2 Antibodies (79) and TRIM2 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TRIM2 23321 Q9C040
TRIM2 80890 Q9ESN6
TRIM2 361970 D3ZQG6
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Top TRIM2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$4,176.33
Details

TRIM2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human

Mouse (Murine)

Rat (Rattus)

More Proteins for Tripartite Motif Containing 2 (TRIM2) Interaction Partners

Human Tripartite Motif Containing 2 (TRIM2) interaction partners

  1. Studies indicate most-studied TRIpartite Motif (TRIM (show TRAT1 Proteins))-NHL proteins TRIM2, TRIM3 (show TRIM3 Proteins), TRIM32 (show TRIM32 Proteins) and TRIM71 (show TRIM71 Proteins), and their mutations have been linked to diseases.

  2. TRIM2 homozygous missense mutation (c.2000A>C; p.D667A) in a patient with peripheral neuropathy and bilateral vocal cord paralysis

  3. The functional role of the C-terminal NHL domain was characterized in TRIM2.

  4. TRIM2 is repressed by miR (show MLXIP Proteins)-9 and -181c, either alone or in combination.

Mouse (Murine) Tripartite Motif Containing 2 (TRIM2) interaction partners

  1. a role for TRIM2 in mediating the p42/p44 (show PSMC6 Proteins) MAPK (show MAPK3 Proteins)-dependent ubiquitination of Bim (show BCL2L11 Proteins) in rapid ischemic tolerance.

  2. Trim2 has an important function in the regulation of axon outgrowth during development.

  3. TRIM2 is an ubiquitin ligase and point to a mechanism regulating neurofilament light subunit metabolism through an ubiquitination pathway that, if deregulated, triggers neurodegeneration

TRIM2 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The protein localizes to cytoplasmic filaments. Its function has not been identified.

Gene names and symbols associated with TRIM2

  • tripartite motif containing 2 (TRIM2)
  • tripartite motif-containing 2 (Trim2)
  • mKIAA0517 protein
  • narf protein
  • RNF86 protein

Protein level used designations for TRIM2

E3 ubiquitin-protein ligase TRIM2 , RING finger protein 86 , tripartite motif protein 2 , tripartite motif protein TRIM2 , tripartite motif-containing 2 , tripartite motif-containing protein 2 , Tripartite motif-containing protein 2 , neural activity-related ring finger protein

GENE ID SPECIES
23321 Homo sapiens
475470 Canis lupus familiaris
538617 Bos taurus
100408235 Callithrix jacchus
80890 Mus musculus
361970 Rattus norvegicus
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