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anti-Trophoblast Glycoprotein (TPBG) Antibodies

TPBG encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. Additionally we are shipping TPBG Proteins (11) and TPBG Kits (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
TPBG 7162 Q13641
TPBG 21983 Q9Z0L0
TPBG 83684 Q5PQV5
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Top anti-TPBG Antibodies at antibodies-online.com

Showing 10 out of 50 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Mouse Sheep Un-conjugated FACS, ICC, WB Detection of 5T4 in D3 Mouse Cell Line by Flow Cytometry. Retinoic acid-treated D3 mouse embryonic stem cell line was stained with Sheep Anti-Mouse 5T4 Antigen Affinity-purified Polyclonal Antibody. 5T4 in D3 Mouse Cell Line. 5T4 was detected in immersion fixed D3 mouse embryonic stem cell line using Sheep Anti-Mouse 5T4 Antigen Affinity-purified Polyclonal Antibody. Specific staining was localized to cytoplasm/membrane. 100 μg Log in to see 6 to 7 Days
$465.94
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB TPBG Antibody (Center)  western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the TPBG antibody detected the TPBG protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Fluorescein FACS Detection of 5T4 in BG01V Human Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human 5T4 Fluorescein-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$334.69
Details
Human Mouse PE FACS Detection of 5T4 in BG01V Human Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human 5T4 PE-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$400.31
Details
Human Mouse Allophycocyanin FACS Detection of 5T4 in BG01V Human Cells by Flow Cytometry. BG01V human embryonic stem cells were stained with Mouse Anti-Human 5T4 APC-conjugated Monoclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$465.94
Details
Human Mouse Un-conjugated FACS Detection of 5T4 in BG01V Human Cells by Flow Cytometry. Differentiated BG01V human embryonic stem cells were stained with Mouse Anti-Human 5T4 Monoclonal Antibody. 100 μg Log in to see 6 to 7 Days
$334.69
Details
Human Mouse Un-conjugated WB TPBG monoclonal antibody (M09), clone 1B6. Western Blot analysis of TPBG expression in HeLa. Detection limit for recombinant GST tagged TPBG is approximately 1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged TPBG is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Mouse Sheep Fluorescein FACS Detection of 5T4 in D3 Mouse Cell Line by Flow Cytometry. D3 mouse embryonic stem cell line was stained with Sheep Anti-Mouse 5T4 Fluorescein-conjugated Antigen Affinity-purified Polyclonal Antibody. 100 Tests Log in to see 6 to 7 Days
$334.69
Details

TPBG Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine) , ,
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Rat (Rattus)


Top referenced anti-TPBG Antibodies

  1. Mouse (Murine) Polyclonal TPBG Primary Antibody for FACS, ICC - ABIN4900172 : Takahashi, Ogawa, Yoshihara, Asahina, Kinoshita, Kitano, Kitsuki, Tatsumi, Okuda, Tatsumi, Wanaka, Hirai, Stern, Tsuboi: A Subtype of Olfactory Bulb Interneurons Is Required for Odor Detection and Discrimination Behaviors. in The Journal of neuroscience : the official journal of the Society for Neuroscience 2016 (PubMed)
    Show all 2 references for ABIN4900172

More Antibodies against TPBG Interaction Partners

Human Trophoblast Glycoprotein (TPBG) interaction partners

  1. In conclusion, the present study provided evidence that TPBG is involved in PDAC metastasis, and that TPBG and its associated signaling pathways may be a suitable target for pancreatic ductal adenocarcinoma therapy.

  2. 5T4 expression is mechanistically associated with the directional movement of cells through epithelial mesenchymal transition, facilitation of CXCL12 (show CXCL12 Antibodies)/CXCR4 (show CXCR4 Antibodies) chemotaxis, blocking of canonical Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) while favouring non-canonical pathway signalling

  3. Tyrosine 325 plus the leucine-rich repeat 1 surface centered on a second exposed aromatic residue, phenylalanine 97, are essential for inhibition of Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) signaling.

  4. The surface expression of 5T4 marks the use of the CXCR4 (show CXCR4 Antibodies) rather than the CXCR7 (show CXCR7 Antibodies) receptor, with distinct consequences for CXCL12 (show CXCL12 Antibodies) exposure.

  5. 5T4 is a potential new antigen for targeted therapies such as immunotherapy in MPM, as it is overexpressed on mesothelioma cells and recognised by 5T4-specific cytotoxic T-cells.

  6. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen

  7. Results sugest that 5T4 is a transient marker of human embryonic stem cell differentiation & that 5T4 phenotype, colony seeding density and culture conditions influence the maintenance of pluripotent hES (show RRBP1 Antibodies) cells and their differentiation to neural lineages.

  8. there is a repertoire of CD8 T cell recognition of 5T4 in normal human donors and some candidate HLA-A*0201 epitopes have been identified

  9. the mRNA expression of trophoblast glycoprotein is up-regulated in cells circulating within blood from women with preeclampsia.

  10. 5T4-based cancer vaccine: cytotoxic T lymphocyte epitopes identified in Trovax-vaccinated colorectal cancer patients

Mouse (Murine) Trophoblast Glycoprotein (TPBG) interaction partners

  1. The surface expression of 5T4 marks the use of the CXCR4 (show CXCR4 Antibodies) rather than the CXCR7 (show CXCR7 Antibodies) receptor, with distinct consequences for CXCL12 (show CXCL12 Antibodies) exposure.

  2. 5T4 overexpression in newborn olfactory bulb interneurons facilitates their dendritic arborization even under a sensory input-deprived condition.

  3. molecular interaction of 5T4 and CXCR4 (show CXCR4 Antibodies) occurring at the cell surface which directly facilitates the biological response to CXCL12 (show CXCL12 Antibodies)

  4. Spry4 (show SPRY4 Antibodies) and Tpbg/5T4 were detected in Kit-immunoreactive cells only in Kit(K641E), but not in Kit(WT/WT) animals.

  5. Glycosylation and epitope mapping of the 5T4 glycoprotein oncofoetal antigen

  6. 5T4 glycoprotein expression is associated with early differentiative events of embryonic stem cells

  7. A limited expression profile of 5T4 may contribute to the migration of actively cycling, undifferentiated epithelial progenitor cells during embryogenesis

  8. Because 5T4 is known to interact with actin cytoskeleton, these observations suggest that 5T4 is involved in the formation or maintenance of strata-specific dendritic ramification or synaptic connection of subsets of local interneurons.

  9. E-cadherin (show CDH1 Antibodies) protein stabilizes cortical actin cytoskeletal arrangement in embryonic stem cells, and this can prevent cell surface localization of the promigratory 5T4 antigen.

TPBG Antigen Profile

Protein Summary

This gene encodes a leucine-rich transmembrane glycoprotein that may be involved in cell adhesion. The encoded protein is an oncofetal antigen that is specific to trophoblast cells. In adults this protein is highly expressed in many tumor cells and is associated with poor clinical outcome in numerous cancers. Alternate splicing in the 5' UTR results in multiple transcript variants that encode the same protein.

Gene names and symbols associated with TPBG

  • trophoblast glycoprotein (TPBG) antibody
  • sc:d0347 (sc:d0347) antibody
  • trophoblast glycoprotein (tpbg) antibody
  • Trophoblast glycoprotein (tpbg) antibody
  • trophoblast glycoprotein (Tpbg) antibody
  • 5T4 antibody
  • 5T4AG antibody
  • AW495680 antibody
  • M6P1 antibody
  • sc:d0323 antibody
  • sc:d0347 antibody
  • tpbg antibody

Protein level used designations for TPBG

trophoblast glycoprotein , 5T4 oncofetal trophoblast glycoprotein , sc:d0347 , Trophoblast glycoprotein , trophoblast glycoprotein-like , 5T4 oncofetal antigen , 5T4 oncotrophoblast glycoprotein

GENE ID SPECIES
462850 Pan troglodytes
481899 Canis lupus familiaris
540358 Bos taurus
772098 Gallus gallus
792712 Danio rerio
100144407 Danio rerio
100286624 Salmo salar
100379816 Xenopus (Silurana) tropicalis
100405225 Callithrix jacchus
100444954 Pongo abelii
7162 Homo sapiens
21983 Mus musculus
83684 Rattus norvegicus
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