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Tropomodulin 3 Proteins (TMOD3)

Blocks the elongation and depolymerization of the actin filaments at the pointed end. Additionally we are shipping Tropomodulin 3 Antibodies (23) and Tropomodulin 3 Kits (3) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TMOD3 50875 Q9JHJ0
Rat TMOD3 TMOD3 300838  
TMOD3 29766 Q9NYL9
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Top Tropomodulin 3 Proteins at antibodies-online.com

Showing 6 out of 7 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$498.21
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

TMOD3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

Top referenced Tropomodulin 3 Proteins

  1. Human TMOD3 Protein expressed in Escherichia coli (E. coli) - ABIN1098347 : Fischer, Yarmola, Weber, Speicher, Speicher, Bubb, Fowler: Tropomodulin 3 binds to actin monomers. in The Journal of biological chemistry 2006 (PubMed)

More Proteins for Tropomodulin 3 (TMOD3) Interaction Partners

Mouse (Murine) Tropomodulin 3 (TMOD3) interaction partners

  1. Tmod3 is a novel Akt2 (show AKT2 Proteins) effector that mediates insulin (show INS Proteins)-induced cortical actin remodelling and subsequent GLUT4 (show SLC2A4 Proteins) membrane insertion

  2. Loss of TMOD3 is associated with hemorrhage, defect in actin polymerization, organization and platelet biogenesis.

  3. Tmod1 (show TMOD1 Proteins) and Tmod3 showed somewhat different tropomyosin (show TPM2 Proteins)-binding site utilization.

  4. Tmod3-/- embryos are defective in definitive erythropoiesis with reduced progenitors, impaired terminal differentiation, and enucleation.

  5. Western blots of Tmod1 (show TMOD1 Proteins)-null RBCs (show SSU1 Proteins) confirm the absence of Tmod1 (show TMOD1 Proteins) and show the presence of Tmod3, which is normally not present in RBCs (show SSU1 Proteins).

  6. Tmod3 and -4 localize to pointed ends in Tmod1 (show TMOD1 Proteins)-null adult muscle

Human Tropomodulin 3 (TMOD3) interaction partners

  1. investigation of biomarkers for early diagnosis of endometriosis: Data suggest that TMOD3, tropomyosin 3, and stomatin-like protein 2 are autoantigens present in blood of women with endometriosis; immunodominant epitopes were identified.

  2. capping of actin filament pointed ends by Tmod3 inhibits cell migration and reveal a novel control mechanism for regulation of actin filaments in lamellipodia.

  3. levels of TM1 (show TPM2 Proteins), TM2 (show TPM2 Proteins) and TM3 (show TPM1 Proteins) are reduced in human transitional cell carcinoma cells, but significantly upregulated by inhibition of the mitogen-activated protein kinase (show MAPK1 Proteins)-signaling pathway

  4. the Tmod3 isoform may regulate actin dynamics differently in cells than the previously described tropomodulin isoforms

  5. findings show that the pointed-end capping protein Tmod3 contributes to epithelial cell shape within confluent monolayers of polarized epithelial cells

Tropomodulin 3 (TMOD3) Protein Profile

Protein Summary

Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton (By similarity).

Gene names and symbols associated with Tropomodulin 3 Proteins (TMOD3)

  • tropomodulin 3 (ubiquitous) (tmod3)
  • tropomodulin 3 (ubiquitous) (TMOD3)
  • tropomodulin 3 (LOC100228347)
  • tropomodulin 3 (ubiquitous) (LOC100338081)
  • tropomodulin 3 (ubiquitous) (LOC100359303)
  • tropomodulin 3 (Tmod3)
  • MGC53545 protein
  • TMOD3 protein
  • tropomodulin-3 protein
  • U-Tmod protein
  • UTMOD protein

Protein level used designations for Tropomodulin 3 Proteins (TMOD3)

tropomodulin 3 (ubiquitous) , tropomodulin 3 , tropomodulin-3-like , tropomodulin 3; ubiquitous tropomodulin , tropomodulin-3 , ubiquitous tropomodulin , ubiquitous tropomodulin U-Tmod

GENE ID SPECIES
379934 Xenopus laevis
467683 Pan troglodytes
549678 Xenopus (Silurana) tropicalis
694478 Macaca mulatta
100026323 Monodelphis domestica
100069657 Equus caballus
100228347 Taeniopygia guttata
100338081 Oryctolagus cuniculus
100359303 Oryctolagus cuniculus
100413944 Callithrix jacchus
100446020 Pongo abelii
100466167 Ailuropoda melanoleuca
100593336 Nomascus leucogenys
50875 Mus musculus
300838 Rattus norvegicus
415421 Gallus gallus
29766 Homo sapiens
487554 Canis lupus familiaris
397556 Sus scrofa
533257 Bos taurus
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