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TPH1 encodes a member of the aromatic amino acid hydroxylase family. Additionally we are shipping Tryptophan Hydroxylase 1 Kits (33) and Tryptophan Hydroxylase 1 Proteins (8) and many more products for this protein.
Showing 10 out of 155 products:
Cow (Bovine) Polyclonal Tryptophan Hydroxylase 1 Primary Antibody for WB - ABIN372733
Johansen, Jennings, Cotton, Kuhn: Phosphorylation and activation of tryptophan hydroxylase by exogenous protein kinase A. in Journal of neurochemistry 1996
Show all 3 references for ABIN372733
Cow (Bovine) Polyclonal Tryptophan Hydroxylase 1 Primary Antibody for IHC (fro), WB - ABIN372732
Martínez, Knappskog, Haavik: A structural approach into human tryptophan hydroxylase and its implications for the regulation of serotonin biosynthesis. in Current medicinal chemistry 2001
Show all 3 references for ABIN372732
Human Monoclonal Tryptophan Hydroxylase 1 Primary Antibody for WB - ABIN1109359
Craig, Boularand, Darmon, Mallet, Craig: Localization of human tryptophan hydroxylase (TPH) to chromosome 11p15.3----p14 by in situ hybridization. in Cytogenetics and cell genetics 1991
Show all 2 references for ABIN1109359
Human Polyclonal Tryptophan Hydroxylase 1 Primary Antibody for IHC (fro), WB - ABIN319127
Haycock, Kumer, Lewis, Vrana, Stockmeier: A monoclonal antibody to tryptophan hydroxylase: applications and identification of the epitope. in Journal of neuroscience methods 2002
Cow (Bovine) Polyclonal Tryptophan Hydroxylase 1 Primary Antibody for WB - ABIN319117
Banik, Wang, Wagner, Kaufman: Interaction of phosphorylated tryptophan hydroxylase with 14-3-3 proteins. in The Journal of biological chemistry 1997
Human Polyclonal Tryptophan Hydroxylase 1 Primary Antibody for EIA, WB - ABIN453433
Kuhn, Arthur, States: Phosphorylation and activation of brain tryptophan hydroxylase: identification of serine-58 as a substrate site for protein kinase A. in Journal of neurochemistry 1997
A gene-expression-based neural code for food abundance that modulates lifespan includes daf-7 that primarily regulates gene-expression variability, while tph-1 primarily regulates the dynamic range of gene-expression responses.
tph-1 mutants failed to exhibit ethanol interference with gustatory plasticity in Caenorhabditis elegans
Associations between serotonin transporter (show SLC6A4 Antibodies) gene and tryptophan hydroxylase 1 polymorphisms and several Temperament and Character Inventory dimensions and subdimensions were revealed in subjects with bipolar disorder.
there was a significant interaction between the TPH1 A218C A/C and 5-HTTLPR (show SLC6A4 Antibodies) S+ gene polymorphisms in opiate-dependent, but not in alcohol-dependent patients.
Polymorphisms in the TPH1 gene may be represented by diminished activity in lateral areas of the PFC (show CFP Antibodies) underlying response inhibition.
Decoy receptor 3 (show TNFRSF6B Antibodies) regulates the expression of tryptophan hydroxylase 1 in rheumatoid synovial fibroblasts
TPH1 is functionally expressed in human coronary artery smooth muscle cells.
This review showed no evidence for the association of antidepressant response with an A218C SNP in the TPH1 gene.
The study provides evidence that A218C/A779C TPH-1 variants may be a risk factor to manifest suicidal behavior at the clinical level, which is in agreement with previously reported meta-analyses.[review and meta-analysis]
TPH1 gene polymorphisms and S100A10 (show S100A10 Antibodies) expression, which correlate with 5-HT (show DDC Antibodies) signaling were associated with ramosetron effectiveness in IBS-D, and may possibly lead to prospective identification of the resistance to treatment.
no significant effects on group differences or effects of exercise interventions for most of the biological parameters, that is, IL-6 (show IL6 Antibodies), neopterin, 5-HIAA and tryptophan
Tph1 and increased EC cell number occurred before the onset of obesity and hyperleptinemi. In addition, leptin (show LEP Antibodies) deficiency was associated with reduced Pax4 (show PAX4 Antibodies) mRNA, oral leptin (show LEP Antibodies) treatment enhanced both Tph1 and Pax4 (show PAX4 Antibodies) mRNA.
Prolactin (show PRL Antibodies)-induced Tph1 expression.
Tph1-deficient mice fed a high-fat diet (HFD) are protected from obesity, insulin (show INS Antibodies) resistance and nonalcoholic fatty liver disease (NAFLD (show TSC2 Antibodies)) while exhibiting greater energy expenditure by brown adipose tissue.
Lack of tryptophan hydroxylase-1 in mice results in gait abnormalities.
ZBP-89 (show ZNF148 Antibodies) directly binds to the Tph1 promoter, which is required for its basal and butyrate-inducible expression.
TPH1 deficiency or inhibition reduces allergic airway inflammation. Platelet-derived 5-HT (show DDC Antibodies) is pivotal in AAI and lack of 5-HT (show DDC Antibodies) leads to impaired Th2 priming capacity of bone marrow dendritic cells.
Data indicate that tryptophan hydroxylase (Tph)1-deficient mice, lacking non-neuronal serotonin, showed mild leukocytosis.
Data show that Tph-1 (tryptophan hydroxylase-1) is a potent regulator of immunity.
Parallel to Tph1 mRNA and protein induction, islet serotonin content increased to a peak level that was 200-fold higher than basal. Interestingly, only a subpopulation of the beta cells was serotonin-positive in vitro and in vivo.
nonneuronal tph1 gene has a role in cardiac function with peripheral serotonin
Review. TPH1 is expressed in the pineal gland and the enterochromaffin cells. Loss of TPH1 gene expression, and thus of peripheral 5-HT (show DDC Antibodies), leads to a cardiac dysfunction phenotype.
This gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger-related traits, bipolar disorder, suicidal behavior, addictions, and others.
, tryptophan 5-monooxygenase
, tryptophan hydroxylase (tryptophan 5-monooxygenase
, TryPtophan Hydroxylase family member (tph-1)
, tryptophan hydroxylase 1 (tryptophan 5-monooxygenase)
, tryptophan hydroxylase 1
, tryptophan 5-hydroxylase 1-like
, tryptophan hydroxylase
, tryptophan 5-hydroxylase 1
, L-tryptophan hydroxylase
, indoleacetic acid-5-hydroxylase
, tryptophan 5-monooxygenase 1
, tryptophan hydroxylase (tryptophan 5-monooxygenase)
, secretion regulating guanine nucleotide exchange factor