Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins (TNFRSF11B)

The protein encoded by TNFRSF11B is a member of the TNF-receptor superfamily. Additionally we are shipping Tumor Necrosis Factor Receptor Superfamily, Member 11b Antibodies (174) and Tumor Necrosis Factor Receptor Superfamily, Member 11b Kits (80) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF11B 4982 O00300
TNFRSF11B 18383 O08712
TNFRSF11B 25341 O08727
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Top Tumor Necrosis Factor Receptor Superfamily, Member 11b Proteins at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 100 μg Log in to see 20 to 21 Days
$250.80
Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Mouse Un-conjugated 25 μg Log in to see 10 to 12 Days
$135.88
Details
HOST_Human Cells Rhesus Monkey Fc Tag 100 μg Log in to see 20 to 21 Days
$272.80
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
HOST_HEK-293 Cells Human Fc Tag Human Osteoprotegerin, Fc Tag on SDS-PAGE under reducing (R) and no-reducing (NR) conditions. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 92%. 100 μg Log in to see 2 to 3 Days
$198.00
Details
HOST_Human Cells Mouse Fc Tag SDS-PAGE 100 μg Log in to see 20 to 21 Days
$272.80
Details
HOST_HEK-293T Human His-DYKDDDDK-Strep II Tag 25 μg Log in to see 11 to 12 Days
$914.29
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details
HOST_Human Human His tag   10 μg Log in to see 15 to 16 Days
$125.00
Details

TNFRSF11B Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , , , , ,
, , ,
Mouse (Murine) , ,
,
Rat (Rattus)

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Formulation and in vitro and in vivo evaluation of a new osteoprotegerin-chitosan gel for bone tissue regeneration

  2. The RANKL/OPG (show TNFSF11 Proteins) ratio significantly increased in the presence of bone metastasis with appropriate sensitivity and specificity (73% and 72%, respectively) at a cutoff of >/=0.14 for the detection of bone metastasis. Serum OPG and RANKL/OPG (show TNFSF11 Proteins) ratios are promising biomarkers for detecting bone metastasis in breast cancer patients.

  3. Osteoprotegerin facilitates pulmonary arterial hypertension pathogenesis by regulating pulmonary arterial smooth muscle cell proliferation via integrin alphavbeta3 (show ITGAV Proteins)/FAK (show PTK2 Proteins)/AKT (show AKT1 Proteins) signaling pathway.

  4. Elevated osteoprotegerin concentration is associated with an increased risk of incident cardiovascular disease in the general population

  5. Physical activity does not increase circulating osteoprotegerin level.

  6. OPG may be a potential driver of lung cancer cells and therefore might have potential in therapy and diagnostics.

  7. our findings suggest OPG is a downstream effector of IL1B (show IL1B Proteins)-mediated invasion in breast cancer cells.

  8. measurement of serum osteoprotegerin concentration might be useful as a surrogate marker for determining bone loss in patients with chronic kidney disease, especially for women, although not so much for men.

  9. In patients with tightly controlled rheumatoid arthritis, serum OPG was inversely associated with progression of joint destruction.

  10. estrogen may post-transcriptionally regulate OPG expression through suppression of miR (show MLXIP Proteins)-145 expression.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. RANK/RANKL (show TNFSF11 Proteins) signaling is involved in the androgen deprivation therapy-induced acceleration of bone metastasis in castration-insensitive prostate cancer and is inhibited by osteoprotegerin to prevent bone metastasis.

  2. endocortical resorption is driven by reduced OPG (show TNFSF11 Proteins) rather than elevated RANKL (show TNFSF11 Proteins) expression

  3. Diabetes significantly increased OPG (show TNFSF11 Proteins) and the OPG (show TNFSF11 Proteins)/TRAIL ratio expression in the aorta, while dyslipidemia was the major determinant of the changes observed in the heart, where it significantly increased OPG (show TNFSF11 Proteins) and reduced TRAIL expression, thus increasing cardiac OPG (show TNFSF11 Proteins)/TRAIL ratio.

  4. These discoveries strongly suggest that Heparan Sulfate plays an active role in regulating OPG-RANKL (show TNFSF11 Proteins) interaction and osteoclastogenesis.

  5. OPG (show TNFSF11 Proteins) plays an important role in regulating bone marrow mesenchymal stem cells differentiation and bone marrow adipogenesis.

  6. These data suggested that OPG (show TNFSF11 Proteins) played an important role in maintaining the homeostasis of articular cartilage of femoral head.

  7. Data show that p38alpha (show MAPK14 Proteins) mitogen-activated protein kinase (show MAPK1 Proteins) (MAPK (show MAPK1 Proteins)) in paired related homeobox 1 (show PRRX1 Proteins) protein (Prx1 (show PRDX1 Proteins)+) bone marrow-derived mesenchymal stromal cells acts to preserve the bone by sustaining osteoprotegerin (OPG) production.

  8. OPG (show TNFSF11 Proteins) expression in chondrocyte increases bone mass in the proximal metaphysis of tibiae through negative regulation of osteoclast formation.

  9. the generation of Rag2GFP+ regulatory T cells is unaltered in Tnfrsf11b(-/-) mice

  10. identify osteoprotegerin as a HIF target gene capable of directing osteoblast-mediated osteoclastogenesis to regulate bone homeostasis

Rabbit Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. The OPG (show TNFSF11 Proteins) expression levels decreased while those of RANKL (show TNFSF11 Proteins) and RUNX2 (show RUNX2 Proteins) increased during orthodontic tooth movement, which suggested that they play a role in the osteogenesis process and the reconstruction of periodontal tissue.

  2. Low-frequency vibration may promote the osteogenic differentiation capability of BMSC probably through regulating the OPG/RANKL (show TNFSF11 Proteins) mRNA expression.

Pig (Porcine) Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) interaction partners

  1. Regional variation of periosteal activity at the mandibular ramus is regulated by differential expression of osteoprotegerin.

Tumor Necrosis Factor Receptor Superfamily, Member 11b (TNFRSF11B) Protein Profile

Protein Summary

Acts as decoy receptor for RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis. Bone homeostasis seems to depend on the local RANKL/OPG ratio. May also play a role in preventing arterial calcification. May act as decoy receptor for TRAIL and protect against apoptosis. TRAIL binding blocks the inhibition of osteoclastogenesis (By similarity).

Gene names and symbols associated with TNFRSF11B

  • tumor necrosis factor receptor superfamily, member 11b (TNFRSF11B)
  • basic transcription factor 3 pseudogene 11 (BTF3P11)
  • tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) (Tnfrsf11b)
  • tumor necrosis factor receptor superfamily, member 11b (Tnfrsf11b)
  • osteoprotegerin (LOC100037695)
  • tumor necrosis factor receptor superfamily, member 11b (tnfrsf11b)
  • BTF3L1 protein
  • HUMBTFB protein
  • ocif protein
  • opg protein
  • TNFRSF11B protein
  • tr1 protein

Protein level used designations for TNFRSF11B

osteoclastogenesis inhibitory factor , osteoprotegerin , tumor necrosis factor receptor superfamily member 11B , Osteoprotegerin , tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin) , tumor necrosis factor receptor superfamily, member 11b , tumor necrosis factor receptor superfamily member 11B-like

GENE ID SPECIES
4982 Homo sapiens
690 Homo sapiens
18383 Mus musculus
25341 Rattus norvegicus
464351 Pan troglodytes
523822 Bos taurus
100037695 Ovis aries
444716 Xenopus laevis
482025 Canis lupus familiaris
701850 Macaca mulatta
100399751 Callithrix jacchus
100433420 Pongo abelii
100465761 Ailuropoda melanoleuca
100599407 Nomascus leucogenys
100348133 Oryctolagus cuniculus
100049688 Sus scrofa
100860896 Capra hircus
100065885 Equus caballus
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