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Tumor Necrosis Factor Receptor Superfamily, Member 21 Proteins (TNFRSF21)

The protein encoded by TNFRSF21 is a member of the TNF-receptor superfamily. Additionally we are shipping TNFRSF21 Antibodies (151) and TNFRSF21 Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
TNFRSF21 27242 O75509
TNFRSF21 94185 Q9EPU5
Rat TNFRSF21 TNFRSF21 316256  
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Top TNFRSF21 Proteins at antibodies-online.com

Showing 10 out of 35 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human Fc Tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Mouse His tag 100 μg Log in to see 16 Days
$382.80
Details
HOST_Human Cells Cynomolgus His tag 100 μg Log in to see 16 Days
$272.80
Details
HOST_Human Cells Human Un-conjugated 100 μg Log in to see 16 Days
$250.80
Details
HOST_Escherichia coli (E. coli) Human His tag 0.05 mg Log in to see 2 to 3 Days
$275.00
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Human Mouse Fc Tag   50 μg Log in to see 5 to 8 Days
$309.75
Details

TNFRSF21 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , , , ,
, , , ,
Mouse (Murine) , , ,
, , ,

Top referenced TNFRSF21 Proteins

  1. Human TNFRSF21 Protein expressed in Human Cells - ABIN2002246 : Kasof, Lu, Liu, Speer, Mongan, Gomes, Lorenzi: Tumor necrosis factor-alpha induces the expression of DR6, a member of the TNF receptor family, through activation of NF-kappaB. in Oncogene 2001 (PubMed)
    Show all 5 references for ABIN2002246

  2. Cynomolgus TNFRSF21 Protein expressed in Human Cells - ABIN2010155 : Pan, Bauer, Haridas, Wang, Liu, Yu, Vincenz, Aggarwal, Ni, Dixit: Identification and functional characterization of DR6, a novel death domain-containing TNF receptor. in FEBS letters 1998 (PubMed)
    Show all 5 references for ABIN2010155

  3. Human TNFRSF21 Protein expressed in Human Cells - ABIN2002248 : Zhao, Yan, Wang, Erickson, Grewal, Dixit: Impaired c-Jun amino terminal kinase activity and T cell differentiation in death receptor 6-deficient mice. in The Journal of experimental medicine 2001 (PubMed)
    Show all 5 references for ABIN2002248

  4. Mouse (Murine) TNFRSF21 Protein expressed in Human Cells - ABIN2007584 : Liu, Heuer, Na, Galbreath, Zhang, Yang, Glasebrook, Song: Accelerated onset and increased severity of acute graft-versus-host disease following adoptive transfer of DR6-deficient T cells. in Journal of immunology (Baltimore, Md. : 1950) 2002 (PubMed)
    Show all 5 references for ABIN2007584

More Proteins for Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) Interaction Partners

Human Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) interaction partners

  1. data identify a new mechanism underlying tumour cell extravasation and metastasis, and suggest endothelial DR6-mediated necroptotic signalling pathways as targets for anti-metastatic therapies

  2. Increase in the expression levels of mRNA and protein for the death receptor 6 is associated with various types of gynaecological malignancy.

  3. Circulating levels of DR6 and Gpm6B (show GPM6B Proteins) correlate with breast cancer tumor grade.

  4. The present findings suggested that DR6 is involved in the pathogenesis of endometriosis by creating the proliferative and anti-apoptotic characteristics of endometriosis.

  5. Our results support the view that DR6 functions with APP (show APP Proteins) to modulate synaptic density in the adult CNS

  6. These results provide direct support for the model that APP (show APP Proteins) and DR6 function cell autonomously and in the same pathway to control pruning

  7. our findings provide new insight into a novel mechanism by which DR6 induces downstream signaling in response to an agonist antibody.

  8. DR6 knockout mice are viable and fertile, and show hyperproliferation of T cells when stimulated.

  9. DR6 mediates T cell proliferation and differentiation in mice.

  10. DR6-induced apoptosis occurs through a new pathway that is different from the type I and type II pathways through interacting with Bax (show BAX Proteins).

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 21 (TNFRSF21) interaction partners

  1. data identify a new mechanism underlying tumour cell extravasation and metastasis, and suggest endothelial DR6-mediated necroptotic signalling pathways as targets for anti-metastatic therapies

  2. This study demonistrated that DR6 to contribute to axonal pruning occurring during experience-dependent cortical plasticity throughout life.

  3. A DR6/p75(NTR (show NGFR Proteins)) complex is responsible for beta-amyloid-induced cortical neuron death.

  4. Pla2g7 (show Lp-PLA2 Proteins) and Tnfrsf21 have been identified as genetic susceptibility to influenza genes in mice.

  5. findings show that DR6 expression is significantly but transiently upregulated only in activated both CD4 (show CD4 Proteins)+ and CD8 (show CD8A Proteins)+ T cells in NF-kappaB (show NFKB1 Proteins) and NF-AT (show NFATC3 Proteins) dependent manner with a contribution of PI3K-dependent signaling

  6. T cells lacking the DR6 receptor generate a severe form of acute graft-versus-host disease with accelerated onset, increased severity, rapid weight loss, and earlier organ damage and mortality.

  7. Enhanced B cell expansion, survival, and humoral responses by targeting death receptor 6.

  8. Death receptor 6 plays an important role in regulating leukocyte infiltration and function in the induction and progression of experimental autoimmune encephalomyelitis.

  9. point to a critical role of DR6 in regulating airway inflammation in the ovalbumin (show OVA Proteins)-induced mouse model of asthma

  10. results indicate that APP (show APP Proteins) and DR6 are components of a neuronal self-destruction pathway, and suggest that an extracellular fragment of APP (show APP Proteins), acting via DR6 and caspase 6 (show CASP6 Proteins), contributes to Alzheimer's disease

TNFRSF21 Protein Profile

Protein Summary

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB and MAPK8/JNK, and induce cell apoptosis. Through its death domain, this receptor interacts with TRADD protein, which is known to serve as an adaptor that mediates signal transduction of TNF-receptors. Knockout studies in mice suggested that this gene plays a role in T-helper cell activation, and may be involved in inflammation and immune regulation.

Gene names and symbols associated with TNFRSF21

  • tumor necrosis factor receptor superfamily, member 21 (TNFRSF21)
  • tumor necrosis factor receptor superfamily, member 21 (tnfrsf21)
  • tumor necrosis factor receptor superfamily, member 21 (LOC100224578)
  • tumor necrosis factor receptor superfamily, member 21 (Tnfrsf21)
  • AA959878 protein
  • BM-018 protein
  • CD358 protein
  • dr6 protein
  • im:6795346 protein
  • MGC146356 protein
  • R74815 protein
  • tnfrsf21 protein
  • TR7 protein
  • wu:fa55e01 protein
  • wu:fb02e11 protein
  • wu:fc29a09 protein
  • wu:fi27h08 protein

Protein level used designations for TNFRSF21

tumor necrosis factor receptor superfamily, member 21 , tumor necrosis factor receptor superfamily member 21-like , TNFR-related death receptor 6 , death receptor 6 , tumor necrosis factor receptor superfamily member 21 , Death receptor 6 , TNFR-related death receptor-6

GENE ID SPECIES
462749 Pan troglodytes
705101 Macaca mulatta
780059 Xenopus (Silurana) tropicalis
100224578 Taeniopygia guttata
100349758 Oryctolagus cuniculus
100386273 Callithrix jacchus
100459882 Pongo abelii
100554405 Anolis carolinensis
27242 Homo sapiens
609964 Canis lupus familiaris
537922 Bos taurus
94185 Mus musculus
316256 Rattus norvegicus
422062 Gallus gallus
564874 Danio rerio
Selected quality suppliers for TNFRSF21 Proteins (TNFRSF21)
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