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Tyrosine-Protein Phosphatase Non-Receptor Type 4 Proteins (PTPN4)

The protein encoded by PTPN4 is a member of the protein tyrosine phosphatase (PTP) family. Additionally we are shipping Tyrosine-Protein Phosphatase Non-Receptor Type 4 Antibodies (20) and Tyrosine-Protein Phosphatase Non-Receptor Type 4 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PTPN4 19258 Q9WU22
PTPN4 5775 P29074
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Top Tyrosine-Protein Phosphatase Non-Receptor Type 4 Proteins at antibodies-online.com

Showing 3 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

PTPN4 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for Tyrosine-Protein Phosphatase Non-Receptor Type 4 (PTPN4) Interaction Partners

Mouse (Murine) Tyrosine-Protein Phosphatase Non-Receptor Type 4 (PTPN4) interaction partners

  1. our results provide new insight into the TLR4 (show TLR4 Proteins) pathway and identify PTPN4 as a specific inhibitor of TRIF (show RNF138 Proteins)-dependent TLR4 (show TLR4 Proteins) pathway.

  2. Tyrosine dephosphorylation events regulated by PTPMEG are important for both motor learning and cerebellar synaptic plasticity.

  3. PTPN3 and PTPN4 are dispensable for TCR signal transduction.

Human Tyrosine-Protein Phosphatase Non-Receptor Type 4 (PTPN4) interaction partners

  1. Deletion of PTPN4 has been reported in monozygotic twins with a Rett syndrome-like phenotype.

  2. The physiologically active PTPN4 two-domain (the PDZ and the phosphatase domains) adopts a predominant compact conformation in solution. PDZ ligand binding restores the catalytic competence of PTPN4 disrupting the transient interdomain communication.

  3. These findings suggest that PTPN4 negatively regulates cell proliferation and motility through dephosphorylation of CrkI.

  4. PTPN4 is dispensable for T cell development and/or T cell effector functions.

Tyrosine-Protein Phosphatase Non-Receptor Type 4 (PTPN4) Protein Profile

Protein Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation.

Gene names and symbols associated with PTPN4

  • tyrosine-protein phosphatase non-receptor type 4 (CpipJ_CPIJ003699)
  • tyrosine-protein phosphatase non-receptor type 4 (Tsp_12341)
  • tyrosine-protein phosphatase non-receptor type 4 (Tsp_14272)
  • protein tyrosine phosphatase, non-receptor type 4 (Ptpn4)
  • protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte) (PTPN4)
  • hPTP-MEG protein
  • MEG protein
  • Ptn4 protein
  • PTPMEG protein
  • PTPMEG1 protein
  • TEP protein
  • TEP/mPTPMEG protein

Protein level used designations for PTPN4

tyrosine-protein phosphatase non-receptor type 4 , testis-enriched protein tyrosine phosphatase , PTPase-MEG1 , megakaryocyte phosphatase , megakaryocyte protein-tyrosine phosphatase , protein tyrosine phosphatase MEG1 , protein-tyrosine phosphatase MEG1

GENE ID SPECIES
6035309 Culex quinquefasciatus
10900222 Trichinella spiralis
10907286 Trichinella spiralis
19258 Mus musculus
5775 Homo sapiens
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