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anti-UBX Domain Protein 6 (UBXN6) Antibodies

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. Additionally we are shipping UBXN6 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
UBXN6 363332  
UBXN6 80700 Q9BZV1
UBXN6 66530 Q99PL6
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Top anti-UBXN6 Antibodies at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of UBXN6 Antibody (C-term) (ABIN651276) in mouse kidney tissue lysates (35 µg/lane).UBXN6 (arrow) was detected using the purified polyclonal antibody. UBXN6 Antibody (C-term) (ABIN651276) IHC analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-UBXN6 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Muscle WB Suggested Anti-UBXN6  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human Muscle 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, IP, WB   50 μg Log in to see 5 to 6 Days
$358.05
Details
Human Mouse Un-conjugated IF, IP, WB   50 μg Log in to see 5 to 6 Days
$358.05
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit APC IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Mouse Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details

UBXN6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Rat (Rattus)


Human , ,
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Mouse (Murine)
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Top referenced anti-UBXN6 Antibodies

  1. Human Polyclonal UBXN6 Primary Antibody for IHC (p), WB - ABIN651276 : Nagahama, Ohnishi, Kawate, Matsui, Miyake, Yuasa, Tani, Tagaya, Tsuji: UBXD1 is a VCP-interacting protein that is involved in ER-associated degradation. in Biochemical and biophysical research communications 2009 (PubMed)
    Show all 3 references for ABIN651276

  2. Human Monoclonal UBXN6 Primary Antibody for IF, IP - ABIN1381743 : Haines, Lee, Beauparlant, Kyle, den Besten, Sweredoski, Graham, Hess, Deshaies: Protein interaction profiling of the p97 adaptor UBXD1 points to a role for the complex in modulating ERGIC-53 trafficking. in Molecular & cellular proteomics : MCP 2012 (PubMed)
    Show all 2 references for ABIN1381743

  3. Human Monoclonal UBXN6 Primary Antibody for IF, IP - ABIN1381742 : Ramkumar, Smith, Akinbamidele, Kapcia, Beauparlant, Haines: Generation and characterization of novel monoclonal antibodies recognizing UBXD1. in Hybridoma (2005) 2009 (PubMed)

More Antibodies against UBXN6 Interaction Partners

Human UBX Domain Protein 6 (UBXN6) interaction partners

  1. UBXD1-N intercalates into the p97 (show EIF4G2 Antibodies)-ND1 (show MT-ND1 Antibodies) interface, thereby modulating interdomain communication of p97 (show EIF4G2 Antibodies) domains and its activity with relevance for disease pathogenesis

  2. Data indicate that endosomal trafficking of CAV1 (show CAV1 Antibodies) depends on ubiquitination of the N-terminal region and the subsequent recruitment of VCP (show vcp Antibodies)-UBXD1.

  3. UBXD1 modulates the trafficking of ERGIC-53 (show LMAN1 Antibodies)-containing vesicles by controlling the interaction of transport factors with the cytoplasmic tail of ERGIC-53 (show LMAN1 Antibodies).

  4. Data show that expression of VCP (show vcp Antibodies) mutant proteins, or siRNA-mediated depletion of UBXD1 leads to a block of CAV1 (show CAV1 Antibodies) transport at the limiting membrane of enlarged endosomes in cultured cells.

  5. UBXD1 is a novel co-factor of the human p97 ATPase (show vcp Antibodies).

  6. An additional p97 (show EIF4G2 Antibodies) binding site in UBXD1 that competed with the p47 (show ING1 Antibodies) cofactor for binding to the N domain of p97 (show EIF4G2 Antibodies) was identified.

  7. these findings suggest that UBXD1 is a regulatory component of endoplasmic reticulum-associated degradation that may modulate the adaptor binding to VCP.

UBXN6 Antigen Profile

Protein Summary

Acts in a complex with VCP and cooperates with USP7 in promoting MDM2 deubiquitination and stabilization. MDM2 stabilization leads to MDM2-dependent TP53 degradation (By similarity).

Gene names and symbols associated with UBXN6

  • UBX domain protein 6 (Ubxn6) antibody
  • UBX domain protein 6 (UBXN6) antibody
  • 1200008L11Rik antibody
  • 2210415J11Rik antibody
  • AU040909 antibody
  • UBXD1 antibody
  • Ubxdc2 antibody

Protein level used designations for UBXN6

UBX domain containing 1 , UBX domain-containing protein 6 , UBX domain protein 6 , UBX domain-containing 1 , UBX domain-containing 2 , UBX domain-containing protein 1

GENE ID SPECIES
363332 Rattus norvegicus
715070 Macaca mulatta
100018491 Monodelphis domestica
100589901 Nomascus leucogenys
80700 Homo sapiens
66530 Mus musculus
507936 Bos taurus
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