You are viewing an incomplete version of our website. Please click to reload the website as full version.

UDP Glucuronosyltransferase 1 Family, Polypeptide A4 Proteins (UGT1A4)

UGT1A4 encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. Additionally we are shipping UGT1A4 Antibodies (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UGT1A4 54657 P22310
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top UGT1A4 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UGT1A4 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4) Interaction Partners

Human UDP Glucuronosyltransferase 1 Family, Polypeptide A4 (UGT1A4) interaction partners

  1. Influence of valproic acid concentration and polymorphism of UGT1A4*3, UGT2B7 -161C > T and UGT2B7*2 on serum concentration of lamotrigine in Chinese epileptic children

  2. This descriptive study examines correlations between concentrations of tamoxifen's glucuronide metabolites and genotypes UGT1A4, UGT2B7, UGT2B15 (show UGT2B15 Proteins) and UGT2B17 in 132 patients with estrogen receptor (show ESR1 Proteins)-positive breast cancer under treatment with tamoxifen

  3. in tumor liver microsomes from HCC patients, either V(max) (maximum reaction rate, R(max) for UGT1A1) or clearance rates (V(max)/K(m), Clint) of UGT1A, UGT1A1, UGT1A4, UGT1A9 and UGT2B7 were lower than those in the adjacent normal liver microsomes

  4. The association between the UGT1A4 promoter and coding region SNPs and the glucuronidation rates of Tam (show CCNA1 Proteins).

  5. Correlation of the UGT1A4 gene polymorphism with serum concentration and therapeutic efficacy of lamotrigine in Han Chinese of Northern China

  6. Human UGT1A4 and UGT1A3 conjugate 25-hydroxyvitamin D3.

  7. the substrate specificity of UGT2B10, highlighting its preference for tertiary amines with higher affinities and clearance values than those of UGT1A4 and UGT1A3.

  8. Present results could be helpful to improve the use of UGT1A4 drug substrates in order to adjust them to the ethnic background of a given population, specifically for Hispanics.

  9. study to determine the allelic frequency of two most common defective alleles: UGT1A4*2 and UGT1A4*3 in a Jordanian population

  10. Polymorphic glucuronidation of olanzapine by uridine diphosphate glucuronosyltransferase 1A4 (UGT1A4) was investigated retrospectively in patient samples

UGT1A4 Protein Profile

Protein Summary

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. This enzyme has some glucuronidase activity towards bilirubin, although is is more active on amines, steroids, and sapogenins.

Gene names and symbols associated with UGT1A4

  • UDP glucuronosyltransferase 1 family, polypeptide A4 (UGT1A4)
  • UDP-glucuronosyltransferase 1-4 (UGT1-4)
  • HUG-BR2 protein
  • UDPGT protein
  • UDPGT 1-4 protein
  • UGT-1D protein
  • UGT1 protein
  • UGT1-04 protein
  • UGT1.4 protein
  • UGT1A4 protein
  • UGT1D protein

Protein level used designations for UGT1A4

UDP glycosyltransferase 1 family, polypeptide A4 , UDP-glucuronosyltransferase 1-4 , UDP-glucuronosyltransferase 1-D , UDP-glucuronosyltransferase 1A4 , bilirubin UDP-glucuronosyltransferase isozyme 2 , bilirubin-specific UDPGT isozyme 2

GENE ID SPECIES
54657 Homo sapiens
100038310 Oryctolagus cuniculus
Selected quality suppliers for UGT1A4 Proteins (UGT1A4)
Did you look for something else?