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UGT1A9 encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. Additionally we are shipping UDP Glucuronosyltransferase 1 Family, Polypeptide A9 Proteins (3) and many more products for this protein.
Showing 10 out of 40 products:
Human Polyclonal UGT1A9 Primary Antibody for ELISA, WB - ABIN565757
Izukawa, Nakajima, Fujiwara, Yamanaka, Fukami, Takamiya, Aoki, Ikushiro, Sakaki, Yokoi: Quantitative analysis of UDP-glucuronosyltransferase (UGT) 1A and UGT2B expression levels in human livers. in Drug metabolism and disposition: the biological fate of chemicals 2009
Show all 2 references for ABIN565757
Human Polyclonal UGT1A9 Primary Antibody for IHC (p), WB - ABIN527130
Hardwick, Ferreira, More, Lake, Lu, Manautou, Slitt, Cherrington: Altered UDP-glucuronosyltransferase and sulfotransferase expression and function during progressive stages of human nonalcoholic fatty liver disease. in Drug metabolism and disposition: the biological fate of chemicals 2013
Show all 2 references for ABIN527130
Suggest that the enzymatic properties of UGT1A9 are considerably different between humans and cynomolgus monkeys, although humUGT1A9 and monUGT1A9 were highly conserved at the amino acid level.
We observed statistically significant associations between SNP and Drug-induced liver injury at both allele and genotype levels of of UGT1A9 promoter
UGT1A10 (show UGT1A10 Antibodies) exhibited somewhat higher BPA (show DST Antibodies) glucuronidation activity than UGT1A9, but it was lower than UGT2A1 and UGT2B15 (show UGT2B15 Antibodies). 4.
in tumor liver microsomes from HCC (show FAM126A Antibodies) patients, either V(max) (maximum reaction rate, R(max) for UGT1A1 (show UGT1A1 Antibodies)) or clearance rates (V(max)/K(m), Clint (show CLINT1 Antibodies)) of UGT1A (show UGT1A1 Antibodies), UGT1A1 (show UGT1A1 Antibodies), UGT1A4 (show UGT1A4 Antibodies), UGT1A9 and UGT2B7 (show UGT2B7 Antibodies) were lower than those in the adjacent normal liver microsomes
Significantly lower estimated glomerular filtration rate of the renal allograft in UGT1A9 c.98C carriers did not translate into decreased allograft survival.
Data shows that UGT1A9*22 allele was significantly less frequent in the Uzbek population compared to the Japanese.
UGT1A9 is the major isoform responsible for the glucuronidations of fraxetin in liver microsomes.
In HeLa cells overexpressing UGT1A9 there was an increase in catalysis and production of luteolin glucuronides.
the UGT1A9 proximal promoter was assumed to change into the non-active form from the original sequence, and this might be one of the reasons for the tissue-specific expression of UGT1A9.
The presence of UGT1A1 (show UGT1A1 Antibodies)*28, UGT1A7 (show UGT1A7 Antibodies)*3, UGT1A9*22 genotypes decreases SN-38 clearance between 20 and 36%
This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols.
UDP glycosyltransferase 1 family, polypeptide A9
, UDP-glucuronosyltransferase 1-9
, UDP-glucuronosyltransferase 1A9
, UDP glucuronosyltransferase 1 family, polypeptide A9
, UDP glycosyl transferase 1A9
, UDP-glucuronosyltransferase 1-I
, UDP glycosyltransferase 1 family polypeptide A12
, UDP-glucuronosyltransferase 1-7
, UDP glycosyltransferase 1 family polypeptide A10
, UDP glycosyltransferase 1 family polypeptide A11
, UDP glycosyltransferase 1 family, polypeptide A10