UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) Proteins (GALNT3)

GALNT3 encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. Additionally we are shipping GALNT3 Antibodies (35) and GALNT3 Kits (1) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GALNT3 14425 P70419
GALNT3 2591 Q14435
Rat GALNT3 GALNT3 366061  
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Top GALNT3 Proteins at antibodies-online.com

Showing 5 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 50 to 55 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 50 to 55 Days
$4,244.78
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$522.50
Details
HOST_Human Human His tag   10 μg Log in to see 15 to 16 Days
$300.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
Details

GALNT3 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)
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Human , , ,
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More Proteins for UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3) Interaction Partners

Mouse (Murine) UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3) interaction partners

  1. Overexpression of Galnt3 in chondrocytes causes dwarfism due to the increase of mucin (show SLC13A2 Proteins)-type O-glycans and a reduction in chondroitin sulfates.

  2. The stabilized Fgf23 (show FGF23 Proteins)-Autosomal dominant hypophosphatemic rickets allele reversed the Galnt3-null phenotype and normalized total Fgf23 (show FGF23 Proteins), serum phosphorus, and bone Fgf23 (show FGF23 Proteins) mRNA.

  3. The deficiency of Galnt3 results in a severe reduction of mucin (show SLC13A2 Proteins)-type O-glycans in spermatids and causes impaired acrosome formation, leading to oligoasthenoteratozoospermia, and Galnt3 may also be involved in the process of fertilization.

  4. A mouse with an N-Ethyl-N-nitrosourea (ENU) Induced Trp589Arg Galnt3 mutation represents a model for hyperphosphataemic familial tumoural calcinosis.

  5. dietary phosphate restriction normalizes biochemical and skeletal phenotypes of Galnt3 knockout mice and, thus, can be an effective therapy for tumoral calcinosis.

  6. Galnt3-deficient mice have a biochemical phenotype of tumoral calcinosis and provide in vivo evidence that Galnt3 plays an essential role in proper secretion of Fgf23 (show FGF23 Proteins) in mice.

Human UDP-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3) interaction partners

  1. Study indicates that loss of GALNT3 occurs in poorly differentiated PDAC, which is associated with the increased aggressiveness and altered glycosylation of ErbB (show EGFR Proteins) family proteins.

  2. The presence of lectin domain T3lec or T4lec during ppGalNAc-T2 and ppGalNAc-T3 catalytic reaction had a clear inhibitory effect on GalNAc-T (show B4GALNT1 Proteins) activity.

  3. GalNAc-T3 might play a role in the pathogenesis of early stage oral squamous cell carcinoma recurrence

  4. MGAT5 (show MGAT5 Proteins) expression is a potential independent adverse prognostic biomarker for recurrence and survival of patients with ccRCC after nephrectomy.

  5. Two microRNAs (miRNAs), miR-17-3p and miR (show MLXIP Proteins)-221, which target GalNAc transferase 3 (GALNT3) mRNA, are rapidly downregulated in human alveolar basal epithelial cells during the early stage of influenza A virus infection.

  6. hyperphosphatemic familial tumoral calcinosis and hyperphosphatemic hyperostosis syndrome caused by a novel GALNT3 mutation

  7. Polymorphisms of rs1863196, rs6710518, rs4667492, rs1349321 and rs6721582 (GALNT3) are associated with bone mineral density.GALNT3 may play a role in genetic susceptibility to postmenopausal osteoporosis in Chinese womeh.

  8. Data are indicative for a strong oncogenic potential of the GALNT3 gene in advanced EOC and identify this transferase as a novel EOC biomarker.

  9. Our data suggest that GalNAc-T3 expression may be a useful indicator of tumor differentiation in thyroid carcinomas.

  10. we integrated different computational tools to perform the in silico analysis of clinically significant mutations (nsSNPs/single amino acid change) at both functional and structural levels, found in human GALNT3, GALNT8 (show GALNT8 Proteins), GALNT12 (show GALNT12 Proteins), and GALNT13 (show GALNT13 Proteins) genes.

GALNT3 Protein Profile

Protein Summary

This gene encodes UDP-GalNAc transferase 3, a member of the GalNAc-transferases family. This family transfers an N-acetyl galactosamine to the hydroxyl group of a serine or threonine residue in the first step of O-linked oligosaccharide biosynthesis. Individual GalNAc-transferases have distinct activities and initiation of O-glycosylation is regulated by a repertoire of GalNAc-transferases. The protein encoded by this gene is highly homologous to other family members, however the enzymes have different substrate specificities.

Gene names and symbols associated with GALNT3

  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (Galnt3)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (GALNT3)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3 (GalNAc-T3) (Galnt3)
  • GalNAc-T3 protein
  • HFTC protein
  • HHS protein

Protein level used designations for GALNT3

UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 3 , galNAc-T3 , polypeptide GalNAc transferase 3 , polypeptide N-acetylgalactosaminyltransferase 3 , pp-GaNTase 3 , ppGaNTase-T3 , protein-UDP acetylgalactosaminyltransferase 3 , GalNAc transferase 3 , polypeptide GalNAc-transferase T3

GENE ID SPECIES
14425 Mus musculus
2591 Homo sapiens
366061 Rattus norvegicus
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