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anti-Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) Antibodies

Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum- associated degradation (ERAD). Additionally we are shipping USP13 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
USP13 8975 Q92995
USP13 72607 Q5BKP2
USP13    
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Top anti-USP13 Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC, ELISA, WB Western blot analysis of extracts from mouse brain cells, using USP13 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using USP13 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-USP13 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Human Placenta WB Suggested Anti-USP13  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated WB Detection of USP13 in HeLa cells expressing exogenous USP13 by anti-USP13 Pab (ABIN388900). (Data provided by Amy Chen, Burnham Institute for Medical Research) 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-USP13 Pab (ABIN388901) is used in Western blot to detect USP13 in HeLa cell lysate. Detection of USP13 in HeLa cells expressing exogenous USP13 by anti-USP13 Pab (ABIN388901). (Data provided by Amy Chen, Burnham Institute for Medical Research) 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Mouse Un-conjugated IP, WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY USP13 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-USP13. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated IP, IHC, WB Immunohistochemical staining of paraffin-embedded breast tissue using anti-USP13 mouse monoclonal antibody. (ABIN2452485, Dilution 1:50) Immunohistochemical staining of paraffin-embedded colon tissue using anti-USP13mouse monoclonal antibody. (ABIN2452485, Dilution 1:50) 100 μL Log in to see 2 to 3 Days
$423.50
Details

USP13 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


Dog (Canine)
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Top referenced anti-USP13 Antibodies

  1. Human Polyclonal USP13 Primary Antibody for EIA, WB - ABIN357544 : Timms, Ansari-Lari, Morris, Brown, Gibbs: The genomic organization of Isopeptidase T-3 (ISOT-3), a new member of the ubiquitin specific protease family (UBP). in Gene 1998 (PubMed)
    Show all 3 references for ABIN357544

  2. Human Polyclonal USP13 Primary Antibody for EIA, IHC (p) - ABIN357545 : Puente, Sánchez, Overall, López-Otín: Human and mouse proteases: a comparative genomic approach. in Nature reviews. Genetics 2003 (PubMed)
    Show all 3 references for ABIN357545

More Antibodies against USP13 Interaction Partners

Human Ubiquitin Specific Peptidase 13 (Isopeptidase T-3) (USP13) interaction partners

  1. Down-regulation of USP13 mediates PTEN (show PTEN Antibodies) protein loss and fibroblast phenotypic change, and thereby plays a crucial role in idiopathic pulmonary fibrosis pathogenesis.

  2. The authors identify USP13 as a gp78 (show AMFR Antibodies)-associated deubiquitinase that eliminates ubiquitin conjugates from Ubl4A (show UBL4A Antibodies) to maintain the functionality of Bag6 (show BAT3 Antibodies).

  3. USP13 is a tumour-suppressing protein that functions through deubiquitylation and stabilization of PTEN (show PTEN Antibodies).

  4. to our knowledge, USP13 is the first deubiquitinating enzymes identified to modulate STAT1 and play a role in the antiviral activity of IFN against DEN-2 replication.

  5. USP10 (show USP10 Antibodies) mediates the deubiquitination of p53 (show TP53 Antibodies), regulating deubiquitination activity of USP10 (show USP10 Antibodies) and USP13 by Beclin1 (show BECN1 Antibodies) provides a mechanism for Beclin1 (show BECN1 Antibodies) to control the levels of p53 (show TP53 Antibodies).

  6. Through deubiquitination, USP13 stabilizes and upregulates MITF (show MITF Antibodies) protein levels.

  7. study identifies a new layer of Siah2 (show SIAH2 Antibodies) regulation mediated by USP13 binding to ubiquitinated Siah2 (show SIAH2 Antibodies) protein with a concomitant inhibitory effect on its activity under normoxia

USP13 Antigen Profile

Protein Summary

Deubiquitinase that mediates deubiquitination of target proteins such as BECN1, MITF, SKP2 and USP10 and is involved in various processes such as autophagy and endoplasmic reticulum- associated degradation (ERAD). Component of a regulatory loop that of BECN1, a key regulator of autophagy, leading to stabilize the PIK3C3/VPS34-containing complexes. Also deubiquitinates USP10, an essential regulator of p53/TP53 stability. In turn, PIK3C3/VPS34- containing complexes regulate USP13 stability, suggesting the existence of a regulatory system by which PIK3C3/VPS34-containing complexes regulate p53/TP53 protein levels via USP10 and USP13. Recruited by nuclear UFD1 and mediates deubiquitination of SKP2, thereby regulating endoplasmic reticulum-associated degradation (ERAD). Mediates stabilization of SIAH2 independently of impairing SIAH2 autoubiquitination. Has a weak deubiquitinase activity in vitro and preferentially cleaves 'Lys-63'-linked polyubiquitin chains. In contrast to USP5, it is not able to mediate unanchored polyubiquitin disassembly. Able to cleave ISG15 in vitro\; however, additional experiments are required to confirm such data (By similarity).

Gene names and symbols associated with USP13

  • ubiquitin specific peptidase 13 (isopeptidase T-3) (USP13) antibody
  • ubiquitin specific peptidase 13 (isopeptidase T-3) (usp13) antibody
  • universal stress protein (usp13) antibody
  • ubiquitin specific peptidase 13 (isopeptidase T-3) (Usp13) antibody
  • 2700071E21Rik antibody
  • AI848077 antibody
  • IsoT-3 antibody
  • ISOT3 antibody

Protein level used designations for USP13

ubiquitin specific peptidase 13 (isopeptidase T-3) , ubiquitin specific protease 13 (isopeptidase T-3) , ubiquitin carboxyl-terminal hydrolase 13-like , ubiquitin thiolesterase 13-like , deubiquitinating enzyme 13 , ubiquitin carboxyl-terminal hydrolase 13 , ubiquitin thioesterase 13 , ubiquitin-specific-processing protease 13 , ubiquitin thiolesterase 13 , universal stress protein , isopeptidase T-3 , Deubiquitinating enzyme 13 , Ubiquitin thioesterase 13 , Ubiquitin-specific-processing protease 13

GENE ID SPECIES
471009 Pan troglodytes
100524109 Sus scrofa
100346991 Oryctolagus cuniculus
429286 Gallus gallus
496675 Xenopus (Silurana) tropicalis
708624 Macaca mulatta
100013861 Monodelphis domestica
100484573 Ailuropoda melanoleuca
100563917 Anolis carolinensis
3127112 Haloarcula marismortui ATCC 43049
8975 Homo sapiens
72607 Mus musculus
478640 Canis lupus familiaris
100065844 Equus caballus
100141289 Bos taurus
Selected quality suppliers for anti-USP13 (USP13) Antibodies
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