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Ubiquitin Specific Peptidase 21 Proteins (USP21)

USP21 encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. Additionally we are shipping USP21 Antibodies (95) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
USP21 27005 Q9UK80
Mouse USP21 USP21 30941 Q9QZL6
USP21 688466 B2GUX4
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Top USP21 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,620.83
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

USP21 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

More Proteins for Ubiquitin Specific Peptidase 21 (USP21) Interaction Partners

Human Ubiquitin Specific Peptidase 21 (USP21) interaction partners

  1. Data show that SUMOylated BANP (show BANP Proteins), E5R, and Nac1 (show NACC1 Proteins) (BEN (show GTF2IRD1 Proteins)) domain 3 (BEND3) stabilizes NoRC component TTF-1 (show NKX2-1 Proteins)-interacting protein 5 (show CAPS Proteins) (Tip5)via association with ubiquitin specific protease 21 (USP21) debiquitinase

  2. The protein stability of IL-33 (show IL33 Proteins) is maintained by USP21 through deubiquitination

  3. Identification of the E3 deubiquitinase ubiquitin-specific peptidase 21 (USP21) as a positive regulator of the transcription factor GATA3 (show GATA3 Proteins)

  4. Study observed a reduction in the number of A549 cells developing a primary cilium upon serum starvation when USP21 was depleted with two independent siRNA oligos.

  5. Study report that USP21 cleaves Ub polymers, and with reduced activity also targets ISG15 (show ISG15 Proteins), but is inactive against NEDD8 (show NEDD8 Proteins).

  6. USP21 plays an important role in the down-regulation of TNFalpha (show TNF Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation through deubiquitinating RIP1 (show UQCRFS1 Proteins).

Mouse (Murine) Ubiquitin Specific Peptidase 21 (USP21) interaction partners

  1. Ubiquitin specific protease 21 is dispensable for normal development, hematopoiesis and lymphocyte differentiation

  2. Overexpression of USP21 inhibited RNA virus-induced RIG-I (show DDX58 Proteins) polyubiquitination and RIG-I (show DDX58 Proteins)-mediated interferon (show IFNA Proteins) signaling, while USP21 deletion resulted in elevated RIG-I (show DDX58 Proteins) polyubiquitination, IRF3 (show IRF3 Proteins) phosphorylation, IFN production, and antiviral responses.

  3. USP21 plays an important role in the down-regulation of TNFalpha (show TNF Proteins)-induced NF-kappaB (show NFKB1 Proteins) activation through deubiquitinating RIP1 (show RALBP1 Proteins).

USP21 Protein Profile

Protein Summary

This gene encodes a member of the C19 peptidase family, also known as family 2 of ubiquitin carboxy-terminal hydrolases. The encoded protein cleaves ubiquitin from ubiquitinated proteins for recycling in intracellular protein degradation. The encoded protein is also able to release NEDD8, a ubiquitin-like protein, from NEDD8-conjugated proteins. This gene has been referred to as USP16 and USP23 but is now known as USP21. Alternatively spliced transcript variants have been described.

Gene names and symbols associated with USP21

  • ubiquitin specific peptidase 21 (USP21)
  • Ubiquitin specific peptidase 21 (LOC100152455)
  • ubiquitin specific peptidase 21 (Usp21)
  • ESTM28 protein
  • Usp16 protein
  • USP21 protein
  • Usp23 protein
  • W53272 protein

Protein level used designations for USP21

ubiquitin specific peptidase 21 , Ubiquitin specific peptidase 21 , NEDD8-specific protease , deubiquitinating enzyme 21 , ubiquitin carboxyl-terminal hydrolase 21 , ubiquitin specific protease 21 , ubiquitin thioesterase 21 , ubiquitin thiolesterase 21 , ubiquitin-specific processing protease 21 , ubiquitin-specific protease 16 , ubiquitin-specific-processing protease 21 , ubiquitin specific protease 23 , ubiquitin-specific protease 21

GENE ID SPECIES
469556 Pan troglodytes
478979 Canis lupus familiaris
719894 Macaca mulatta
100028924 Monodelphis domestica
100066197 Equus caballus
100152455 Sus scrofa
100413038 Callithrix jacchus
100431690 Pongo abelii
100483223 Ailuropoda melanoleuca
100601460 Nomascus leucogenys
27005 Homo sapiens
534273 Bos taurus
30941 Mus musculus
688466 Rattus norvegicus
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