You are viewing an incomplete version of our website. Please click to reload the website as full version.

Ubiquitin-Conjugating Enzyme E2K Proteins (UBE2K)

The protein encoded by UBE2K belongs to the ubiquitin-conjugating enzyme family. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2K Antibodies (107) and Ubiquitin-Conjugating Enzyme E2K Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBE2K 3093 P61086
Mouse UBE2K UBE2K 53323 P61087
Rat UBE2K UBE2K 289623  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top Ubiquitin-Conjugating Enzyme E2K Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag 50 μg Log in to see 21 to 26 Days
$313.50
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 5 Days
$121.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   3 nM Log in to see 2 to 3 Days
$357.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,482.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 10 to 12 Days
$237.60
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

UBE2K Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, ,

Top referenced Ubiquitin-Conjugating Enzyme E2K Proteins

  1. Human UBE2K Protein expressed in Escherichia coli (E. coli) - ABIN667870 : Pichler, Knipscheer, Oberhofer, van Dijk, Körner, Olsen, Jentsch, Melchior, Sixma: SUMO modification of the ubiquitin-conjugating enzyme E2-25K. in Nature structural & molecular biology 2005 (PubMed)

More Proteins for Ubiquitin-Conjugating Enzyme E2K (UBE2K) Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2K (UBE2K) interaction partners

  1. The crystal structure of a Ube2K~ubiquitin conjugate has been described, and it was shown that even though it is monomeric, Ube2K can synthesize Lys48-linked ubiquitin chains.

  2. Hip2, a ubiquitin-conjugating enzyme (show Ube2t Proteins), can overcome radiation-induced G2/M cell cycle arrest and trigger the entry into mitosis.

  3. An extract of bark from the tropical rainforest plant Byrsonima crassifolia was screened for inhibition of diubiquitin (show UBD Proteins) formation by the human ubiquitin-conjugating enzyme E2-25K.

  4. one of the roles of the C-terminal UBA domain, in the context of E2-25K, is to increase processivity in Lys48-linked polyubiquitin (show UBB Proteins) chain synthesis, possibly through increased binding to the ubiquitinated substrate.

  5. Results suggest that the interaction between E2-25K and UBB (show UBB Proteins)(+1) is critical for the synthesis and accumulation of UBB (show UBB Proteins)(+1)-anchored polyubiquitin (show UBB Proteins), which results in proteasomal inhibition and neuronal cell death.

  6. This study suggests that Hip2 might be involved in the regulation of Smac (show DIABLO Proteins)-mediated apoptosis.

  7. Results suggest that in permeabilized, US11-expressing cells polyubiquitination of the MHC class I heavy chain substrate can be catalyzed by E2-25K.

  8. E2-25K is involved in aggregate formation of expanded polyglutamine proteins and polyglutamine-induced cell death.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2K (UBE2K) interaction partners

  1. E2-25K/Hip-2 is thus an essential upstream regulator of the expression and activation of caspase-12 in endoplasmic reticulum stress-mediated Abeta (show APP Proteins) neurotoxicity.

Ubiquitin-Conjugating Enzyme E2K (UBE2K) Protein Profile

Protein Summary

The protein encoded by this gene belongs to the ubiquitin-conjugating enzyme family. This protein interacts with RING finger proteins, and it can ubiquitinate huntingtin, the gene product for Huntington's disease. Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases, a role in the dislocation of newly synthesized MHC class I heavy chains from the endoplasmic reticulum, and involvement in foam cell formation. Multiple transcript variants encoding different isoforms have been identified for this gene.

Gene names and symbols associated with UBE2K

  • ubiquitin-conjugating enzyme E2K (ube2k)
  • ubiquitin-conjugating enzyme E2K (UBE2K)
  • ubiquitin-conjugating enzyme E2K (Ube2k)
  • ubiquitin-conjugating enzyme E2Kb (UBC1 homolog, yeast) (ube2kb)
  • AW492011 protein
  • D5Ertd601e protein
  • E2-25k protein
  • Hip2 protein
  • Hypg protein
  • Lig protein
  • UBC1 protein
  • ube2k protein
  • zgc:103472 protein

Protein level used designations for UBE2K

ubiquitin-conjugating enzyme E2K (UBC1 homolog) , huntingtin interacting protein 2 , ubiquitin-conjugating enzyme E2-25K , ubiquitin-conjugating enzyme E2K (UBC1 homolog, yeast) , ubiquitin-conjugating enzyme E2 K , ubiquitin-conjugating enzyme E2-25 kDa , E2(25K) , HIP-2 , huntingtin-interacting protein 2 , ubiquitin carrier protein , ubiquitin-conjugating enzyme E2(25K) , ubiquitin-conjugating enzyme E2-25 KDA , ubiquitin-protein ligase

GENE ID SPECIES
448153 Xenopus (Silurana) tropicalis
461178 Pan troglodytes
699734 Macaca mulatta
3093 Homo sapiens
379982 Xenopus laevis
428787 Gallus gallus
609531 Canis lupus familiaris
281225 Bos taurus
53323 Mus musculus
289623 Rattus norvegicus
30100 Danio rerio
Selected quality suppliers for Ubiquitin-Conjugating Enzyme E2K Proteins (UBE2K)
Did you look for something else?