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Ubiquitin-Conjugating Enzyme E2L 6 Proteins (UBE2L6)

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Additionally we are shipping Ubiquitin-Conjugating Enzyme E2L 6 Antibodies (69) and Ubiquitin-Conjugating Enzyme E2L 6 Kits (9) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBE2L6 9246 O14933
Mouse UBE2L6 UBE2L6 56791 Q9QZU9
UBE2L6 295704 Q4V8J2
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Top Ubiquitin-Conjugating Enzyme E2L 6 Proteins at antibodies-online.com

Showing 10 out of 17 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$407.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 16 Days
$437.80
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,339.33
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,339.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$467.86
Details
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 10 to 12 Days
$237.60
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

UBE2L6 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Top referenced Ubiquitin-Conjugating Enzyme E2L 6 Proteins

  1. Human UBE2L6 Protein expressed in Escherichia coli (E. coli) - ABIN667729 : Ardley, Rose, Tan, Leek, Markham, Robinson: Genomic organization of the human ubiquitin-conjugating enzyme gene, UBE2L6 on chromosome 11q12. in Cytogenetics and cell genetics 2000 (PubMed)
    Show all 2 references for ABIN667729

More Proteins for Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) interaction partners

  1. Data indicate that reduced expression of the ubiquitin-conjugating enzyme (show Ube2t Proteins) UbcH8 (show UBE2E2 Proteins) protein correlated with poor outcome in nasopharyngeal carcinoma (NPC (show NPC1 Proteins)) patients.

  2. study reports that UBCH8 (show UBE2E2 Proteins) and UBE2G1 (show Ube2g1 Proteins) and UBE2G2 (show UBE2G2 Proteins) cooperate with CRL4Cdt2 in promoting the polyubiquitylation and subsequent degradation of p21 (show CDKN1A Proteins) and Cdt1 (show CDT1 Proteins), respectively

  3. gain and loss-of-function approaches show that UBCH8 (show UBE2E2 Proteins) and the ubiquitin-ligase SIAH1 physically interact with and target FLT3 (show FLT3 Proteins)-ITD for proteasomal degradation

  4. The structure of UbcH8 does not undergo a significant conformational change upon forming a complex with ubiquitin.

  5. Quantitative-PCR and Northern analysis confirmed down-regulation of UCRP and UBE2L6 with BRCA2 (show BRCA2 Proteins) knockdown, respectively.

  6. Ube1L (show UBA7 Proteins) was required for transfer of ISG15 (show ISG15 Proteins) to UbcH8 (show UBE2E2 Proteins) and for binding of Ube1L (show UBA7 Proteins) to UbcH8 (show UBE2E2 Proteins)

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) interaction partners

  1. we have identified a loss-of-function mutation in Ube2l6 that contributes to the chromosome 2 obesity quantitative trait locus (show MC3R Proteins).

  2. Ubc8 (show UBE2H Proteins) is a major ISG15 (show ISG15 Proteins)-conjugating enzyme responsible for protein ISGylation upon interferon (show IFNA Proteins) stimulation

Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) Protein Profile

Protein Summary

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Gene names and symbols associated with UBE2L6

  • ubiquitin-conjugating enzyme E2L 6 (UBE2L6)
  • ubiquitin-conjugating enzyme E2L 6 (LOC100349814)
  • ubiquitin-conjugating enzyme E2L 6 (Ube2l6)
  • 2810489I21Rik protein
  • RIG-B protein
  • Ubce8 protein
  • UBCH8 protein
  • UbcM8 protein
  • UBE2L6 protein

Protein level used designations for UBE2L6

ubiquitin-conjugating enzyme E2L 6 , ubiquitin/ISG15-conjugating enzyme E2 L6 , retinoic acid induced gene B protein , retinoic acid-induced gene B protein , ubiquitin carrier protein L6 , ubiquitin-protein ligase L6 , E2 ubiquitin conjugating enzyme , ubiquitin-conjugating enzyme 8 , ubcM8 , Ubiquitin carrier protein L6 , Ubiquitin-protein ligase L6

GENE ID SPECIES
466588 Pan troglodytes
475967 Canis lupus familiaris
100349814 Oryctolagus cuniculus
100514753 Sus scrofa
9246 Homo sapiens
56791 Mus musculus
295704 Rattus norvegicus
509471 Bos taurus
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