UBE2L6 Protein (His tag)
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- Target See all UBE2L6 Proteins
- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
- Protein Type
- Recombinant
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Origin
- Human
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Source
- Escherichia coli (E. coli)
- Purification tag / Conjugate
- This UBE2L6 protein is labelled with His tag.
- Purpose
- Recombinant Human Ube2L6 Protein (His Tag)
- Sequence
- Met 1-Ser 153
- Characteristics
- A DNA sequence encoding the human UBE2L6 isoform 1 (O14933-1) (Met 1-Ser 153) was expressed, with a polyhistide tag at the N-terminus.
- Purity
- > 96 % as determined by reducing SDS-PAGE.
- Top Product
- Discover our top product UBE2L6 Protein
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Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-153) protein (His tag)
UBE2L6 Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB
Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-153) protein (GST tag)UBE2L6 Origin: Human Host: Wheat germ Recombinant ELISA, WB, AA, AP
Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-152) protein (His tag)UBE2L6 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % by SDS PAGE SDS
Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (AA 1-153) protein (Strep Tag)Crystallography grade UBE2L6 Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS
Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (Transcript Variant 2) protein (Myc-DYKDDDDK Tag)UBE2L6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6) (Transcript Variant 1) protein (Myc-DYKDDDDK Tag)UBE2L6 Origin: Human Host: HEK-293 Cells Recombinant > 80 % as determined by SDS-PAGE and Coomassie blue staining AbP, STD
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- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Please refer to the printed manual for detailed information.
- Buffer
- Lyophilized from sterile 20 mM Tris, 0.1 % Brij35, pH 8.5
- Storage
- 4 °C,-20 °C,-80 °C
- Storage Comment
- Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
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- Target
- UBE2L6 (Ubiquitin-Conjugating Enzyme E2L 6 (UBE2L6))
- Alternative Name
- Ube2L6 (UBE2L6 Products)
- Synonyms
- UBE2L6 Protein, RIG-B Protein, UBCH8 Protein, 2810489I21Rik Protein, Ubce8 Protein, Ubcm8 Protein, UbcM8 Protein, ubiquitin conjugating enzyme E2 L6 Protein, ubiquitin-conjugating enzyme E2L 6 Protein, UBE2L6 Protein, Ube2l6 Protein
- Background
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Background: UBCH8, also known as UBE2L6, belongs to the ubiquitin-conjugating enzyme family. The family of ubiquitin-conjugating (E2) enzymes is characterized by the presence of a highly conserved ubiquitin-conjugating (UBC) domain. These domains accommodate the ATP-activated ubiquitin (Ub) or ubiquitin-like (UBL) protein via a covalently linked thioester onto its active-site residue. E2 enzymes act via selective protein-protein interactions with the E1 and E3 enzymes and connect activation to covalent modification. By doing so, E2s differentiate effects on downstream substrates, either with a single Ub/UBL molecule or as a chain. UBCH8 is highly similar in primary structure to the enzyme encoded by the UBE2L3 gene. It catalyzes the covalent attachment of ubiquitin or ISG15 to other proteins. UBCH8 functions in the E6/E6-AP-induced ubiquitination of p53/TP53 and promotes ubiquitination and subsequent proteasomal degradation of FLT3. At protein level, it is present in natural killer cells.
Synonym: Ubiquitin/ISG15-Conjugating Enzyme E2 L6, Retinoic Acid-Induced Gene B Protein, RIG-B, UbcH8, Ubiquitin Carrier Protein L6, Ubiquitin-Protein Ligase L6, UBE2L6, UBCH8
- Molecular Weight
- 19.6 kDa
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