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Ubiquitin-Conjugating Enzyme E2S Proteins (UBE2S)

UBE2S encodes a member of the ubiquitin-conjugating enzyme family. Additionally we are shipping UBE2S Antibodies (150) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
UBE2S 27338 Q16763
Mouse UBE2S UBE2S 77891 Q921J4
UBE2S 292588 B5DFI8
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Top UBE2S Proteins at antibodies-online.com

Showing 10 out of 19 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$242.00
Details
HOST_Escherichia coli (E. coli) Human GST tag   50 μg Log in to see 5 Days
$126.50
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Lithobates catesbeiana His tag   1 mg Log in to see 56 to 66 Days
$2,520.83
Details
Yeast Xenopus tropicalis His tag   1 mg Log in to see 56 to 66 Days
$2,520.83
Details
Yeast Zebrafish His tag   1 mg Log in to see 56 to 66 Days
$2,552.00
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,557.50
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$2,557.50
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$273.57
Details

UBE2S Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Rat (Rattus)

Top referenced UBE2S Proteins

  1. Human UBE2S Protein expressed in Escherichia coli (E. coli) - ABIN666888 : Windheim, Peggie, Cohen: Two different classes of E2 ubiquitin-conjugating enzymes are required for the mono-ubiquitination of proteins and elongation by polyubiquitin chains with a specific topology. in The Biochemical journal 2008 (PubMed)
    Show all 2 references for ABIN666888

More Proteins for Ubiquitin-Conjugating Enzyme E2S (UBE2S) Interaction Partners

Human Ubiquitin-Conjugating Enzyme E2S (UBE2S) interaction partners

  1. Study identified APC (show APC Proteins)/C substrates, including the kinase Nek2A (show NEK2 Proteins), that require Ube2S for degradation. The reconstitution of Nek2A (show NEK2 Proteins)-ubiquitylation revealed that Ube2S does not simply extend a conjugate but instead branches multiple K11-linked chains off the assemblies produced by Ube2C (show UBE2C Proteins).

  2. E2-EPF is overexpressed in cervical cancer and associates with tumor growth

  3. These findings reveal deregulation of the oxygen-sensing pathway impinging on the positive feedback mechanism of HIF1 (show HIF1A Proteins)-mediated regulation of E2-EPF in papillary renal cell carcinoma (show MOK Proteins).

  4. Linkage-specific ubiquitin chain formation by Ube2S is the result of substrate-assisted catalysis.

  5. K11 specificity is determined by an E2 enzyme, UBE2S/E2-EPF, that elongates ubiquitin chains after the substrates are pre-ubiquitinated by UbcH10 (show UBE2C Proteins) or UbcH5 (show UBE2D1 Proteins).

  6. E2-EPF UCP (show UCP1 Proteins) expression induced by growth factors or serum increased HIF-1alpha (show HIF1A Proteins) protein level under non-hypoxic conditions, suggesting that the Egr-1 (show EGR1 Proteins)/SRF-UCP (show UCP1 Proteins)-VHL (show VHL Proteins) pathway is in part responsible for the increased HIF-1alpha (show HIF1A Proteins) protein level

  7. Results suggest that UCP (show UCP1 Proteins) was significantly associated with poor prognosis of esophageal cancer and may be a new molecular target for therapeutic intervention for esophageal squamous cell carcinoma.

  8. UBE2S functions with the APC (show APC Proteins)/C in a two-step mechanism to control substrate ubiquitylation that is essential for mitotic exit after prolonged SAC (show ADCY10 Proteins) activation, providing a new model for APC (show APC Proteins)/C function in human cells

  9. UbcH10 (show UBE2C Proteins) and Ube2S constitute a physiological E2-module for anaphase-promoting complex, the activity of which is required for spindle assembly and cell division.

Mouse (Murine) Ubiquitin-Conjugating Enzyme E2S (UBE2S) interaction partners

  1. alongside their canonical function in protein degradation, Ube2C (show UBE2C Proteins) and -S also control the extrusion of the first polar body.

UBE2S Protein Profile

Protein Summary

This gene encodes a member of the ubiquitin-conjugating enzyme family. The encoded protein is able to form a thiol ester linkage with ubiquitin in a ubiquitin activating enzyme-dependent manner, a characteristic property of ubiquitin carrier proteins.

Gene names and symbols associated with UBE2S

  • ubiquitin-conjugating enzyme E2S (UBE2S)
  • ubiquitin-conjugating enzyme E2S (ATEG_00324)
  • ubiquitin-conjugating enzyme e2S (Smp_180170)
  • ubiquitin-conjugating enzyme E2S (MCYG_01532)
  • ubiquitin-conjugating enzyme E2 S (ube2s)
  • ubiquitin-conjugating enzyme E2S (Ube2s)
  • ubiquitin-conjugating enzyme E2S (ube2s-b)
  • zgc:114060 (zgc:114060)
  • 0910001J09Rik protein
  • 6720465F12Rik protein
  • AA409170 protein
  • DDBDRAFT_0188215 protein
  • DDBDRAFT_0305006 protein
  • DDB_0188215 protein
  • DDB_0305006 protein
  • e2-epf protein
  • e2epf protein
  • epf5 protein
  • RGD1564746 protein
  • ube2s protein
  • ube2s.1 protein
  • ube2s.1-b protein

Protein level used designations for UBE2S

ubiquitin-conjugating enzyme E2S , ubiquitin-conjugating enzyme E2 S , ubiquitin-conjugating enzyme e2S , E2-EPF5 , ubiquitin carrier protein S , ubiquitin-conjugating enzyme E2-24 kD , ubiquitin-conjugating enzyme E2-24 kDa , ubiquitin-conjugating enzyme E2-EPF5 , ubiquitin-protein ligase S , ubiquitin carrier protein , Ubiquitin carrier protein S-B , Ubiquitin-protein ligase S-B , ubiquitin-conjugating enzyme E2 S-B , ubiquitin-conjugating enzyme E2S, gene 1

GENE ID SPECIES
456304 Pan troglodytes
700592 Macaca mulatta
4355076 Aspergillus terreus NIH2624
8355659 Schistosoma mansoni
9230736 Arthroderma otae CBS 113480
8626920 Dictyostelium discoideum AX4
27338 Homo sapiens
403671 Canis lupus familiaris
77891 Mus musculus
379075 Xenopus laevis
617703 Bos taurus
292588 Rattus norvegicus
565498 Danio rerio
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