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Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) Proteins (Galnt1)

Galnt1 encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. Additionally we are shipping Galnt1 Antibodies (21) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Galnt1 14423 O08912
Galnt1 2589 Q10472
Galnt1 79214 Q10473
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Top Galnt1 Proteins at antibodies-online.com

Showing 7 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,600.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

Galnt1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human , , ,
, ,
Rat (Rattus)

More Proteins for Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) Interaction Partners

Mouse (Murine) Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) interaction partners

  1. Study show that in Galnt1 null mouse, there is compromised cardiac function that mimics human congenital heart disease suggesting that Galnt1 expression is required for normal heart valve development.

  2. The GALNT1 is the glycosyltransferase (show GTDC2 Proteins) enzyme family covering a single known glycosidic linkage.

  3. Polypeptide GalNAcT (show B4GALNT1 Proteins)-1 plays a predominant role in leukocyte recruitment in vivo by attaching functionally relevant O-linked glycans to L-selectin (show SELL Proteins) ligands.

  4. Growth factor stimulation regulates O-glycosylation initiation in a Src (show SRC Proteins)-dependent fashion by GalNac-T (show B4GALNT1 Proteins) redistribution from golgi to the endoplasmic reticulum.

  5. ppGalNAcT-1 to be indispensable for O-glycosylation at specific sites of the bone glycoproteins OPN (show SPP1 Proteins) and BSP (show KLK6 Proteins).

Human Udp-N-Acetyl-alpha-D-Galactosamine:polypeptide N-Acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1) interaction partners

  1. Expression of GALNT3 (show GALNT3 Proteins) was reduced in CAD patients, and down regulation of GALNT3 (show GALNT3 Proteins) contributed to endothelial injury by promoting apoptosis and up-regulating the expression of MMP-2 (show MMP2 Proteins) and MMP-14 (show MMP14 Proteins) genes via p38 MAPK (show MAPK14 Proteins) activation.

  2. appears to be responsive to the inhibition of GALNT1 and SHH (show SHH Proteins) signaling

  3. Study demonstrates that down-regulation of GALNT1 is sufficient to suppress malignant phenotype of HCC (show FAM126A Proteins) cells by decreasing EGFR (show EGFR Proteins) signaling.

  4. The GALNT1 is the glycosyltransferase (show GTDC2 Proteins) enzyme family covering a single known glycosidic linkage.

  5. Utilizing unnatural glycopeptide substrates for GalNAc-T3 we demonstrated that the GalNAc-specific sugar recognition of the lectin domain regulates further glycosylation.

  6. Growth factor stimulation regulates O-glycosylation initiation in a Src (show SRC Proteins)-dependent fashion by GalNac-T (show B4GALNT1 Proteins) redistribution from golgi to the endoplasmic reticulum.

  7. the present analysis fails to replicate an earlier reported association of a GALNT1 variant with risk of ovarian cancer

  8. First simultaneous kinetic description of O-glycosylation events by recombinant UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase (show B4GALNT2 Proteins) I at all putative O-glycosylation sites within human mucin (show SLC13A2 Proteins) MUC1 (show MUC1 Proteins) containing 5 tandem repeats.

  9. The results indicated that IL-4 (show IL4 Proteins)-treated LS174T cells are able to produce mucins with a higher degree of O-glycosylation than untreated counterparts.

  10. GalNAc T10 (show GALNT10 Proteins) has a large and pronounced glycopeptide preference for Ser (show SIGLEC1 Proteins)/Thr (show TRH Proteins)-O-GalNAc only at the +1 position from the acceptor site, whereas T1 and T2 have significantly reduced and variable preferences for Ser (show SIGLEC1 Proteins)/Thr (show TRH Proteins)-O-GalNAc.

Galnt1 Protein Profile

Protein Summary

This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. Transcript variants derived from this gene that utilize alternative polyA signals have been described in the literature.

Gene names and symbols associated with Galnt1

  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (galnt1)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (GALNT1)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (LOC100229109)
  • polypeptide N-acetylgalactosaminyltransferase 1-like (LOC100738545)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (Galnt1)
  • UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) (Galnt1)
  • GALNAC-T1 protein
  • GALNT1 protein

Protein level used designations for Galnt1

polypeptide N-acetylgalactosaminyltransferase 1 , UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 1 (GalNAc-T1) , polypeptide N-acetylgalactosaminyltransferase 1-like , UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase 1 , galNAc-T1 , polypeptide GalNAc transferase 1 , pp-GaNTase 1 , ppGaNTase-T1 , protein-UDP acetylgalactosaminyltransferase 1 , GalNAc transferase 1 , polypeptide GalNAc transferase T1

GENE ID SPECIES
398911 Xenopus laevis
420955 Gallus gallus
468521 Pan troglodytes
480161 Canis lupus familiaris
594943 Xenopus (Silurana) tropicalis
708930 Macaca mulatta
100010982 Monodelphis domestica
100181305 Ciona intestinalis
100229109 Taeniopygia guttata
100390797 Callithrix jacchus
100439914 Pongo abelii
100466565 Ailuropoda melanoleuca
100544386 Meleagris gallopavo
100553448 Anolis carolinensis
100605635 Nomascus leucogenys
100738545 Sus scrofa
14423 Mus musculus
2589 Homo sapiens
79214 Rattus norvegicus
282241 Bos taurus
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