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MYB encodes a transcription factor that is a member of the MYB family of transcription factor genes. Additionally we are shipping MYB Kits (12) and MYB Proteins (4) and many more products for this protein.
Showing 10 out of 242 products:
Human Monoclonal MYB Primary Antibody for WB - ABIN1944794
Majello, Kenyon, Dalla-Favera: Human c-myb protooncogene: nucleotide sequence of cDNA and organization of the genomic locus. in Proceedings of the National Academy of Sciences of the United States of America 1987
Show all 3 references for ABIN1944794
Bonobo Polyclonal MYB Primary Antibody for EIA, WB - ABIN401455
Sramko, Markus, Kabát, Wolff, Bies: Stress-induced inactivation of the c-Myb transcription factor through conjugation of SUMO-2/3 proteins. in The Journal of biological chemistry 2006
Show all 2 references for ABIN401455
Human Polyclonal MYB Primary Antibody for IHC, ELISA - ABIN1532156
Westin, Gorse, Clarke: Alternative splicing of the human c-myb gene. in Oncogene 1990
Show all 2 references for ABIN1532156
Human Polyclonal MYB Primary Antibody for IHC, ELISA - ABIN1531346
Dasgupta, Reddy: Identification of alternatively spliced transcripts for human c-myb: molecular cloning and sequence analysis of human c-myb exon 9A sequences. in Oncogene 1990
Show all 2 references for ABIN1531346
Human Polyclonal MYB Primary Antibody for IHC (p), IHC - ABIN253301
Clappier, Cuccuini, Kalota, Crinquette, Cayuela, Dik, Langerak, Montpellier, Nadel, Walrafen, Delattre, Aurias, Leblanc, Dombret, Gewirtz, Baruchel, Sigaux, Soulier: The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children. in Blood 2007
Human Monoclonal MYB Primary Antibody for IHC (p), IP - ABIN119193
Sleeman: Xenopus A-myb is expressed during early spermatogenesis. in Oncogene 1993
Cow (Bovine) Polyclonal MYB Primary Antibody for EIA, WB - ABIN498072
Fahl, Crittenden, Allman, Bender: c-Myb is required for pro-B cell differentiation. in Journal of immunology (Baltimore, Md. : 1950) 2009
These findings reveal that miR (show MLXIP Antibodies)-150 acts as a pivotal regulator of pressure overload-induced cardiac fibrosis by regulating c-Myb.
MYB and C/EBPalpha (show CEBPA Antibodies) activities are inter-dependent in controlling Flt3 (show FLT3 Antibodies) expression to influence lineage commitment of multipotential progenitors.
Myb regulates Cyclin E1 (show CCNE1 Antibodies) expression in normal gastrointestinal tract epithelial cells and is required during intestinal tumorigenesis
Identify regulatory link between Nkx2-1 (show NKX2-1 Antibodies), miR (show MLXIP Antibodies)-200c, and the transcription factors Nfib (show NFIB Antibodies) and Myb, adding new players to the regulatory mechanisms driven by Nkx2-1 (show NKX2-1 Antibodies) in lung epithelial cells that may have implications in lung development and tumorigenesis.
Myb has a role in K14 (show KRT14 Antibodies)+ epithelial cells in the preservation of mouse adult skin integrity and function in a process involving TGFbeta (show TGFB1 Antibodies) and collagen type I
results of this study demonstrate that the c-Myb transcription factor is involved in the regulation and promotion of endochondral bone formation
The transcription factor c-Myb (Myb) is expressed preferentially by immature natural killer cells, is a direct target of miR (show MLXIP Antibodies)-15/16, and is increased in 15a/16-1 floxed knockout natural killer cells.
results show that a p63 (show CKAP4 Antibodies)(-) Myb(+) population of airway epithelial cells represents a distinct intermediate stage of differentiation
The discrimination of HSC (show FUT1 Antibodies) subpopulations based on c-Myb protein levels is not reflected in the levels of c-myb mRNA, there being no more than a 1.3-fold difference comparing c-Myb(low) and c-Myb(high) HSCs.
c-Myb plays an essential, novel role in establishing the long-lived plasma cell population in the bone marrow via responsiveness to chemokine (show CCL1 Antibodies) migration cues.
c-Myb is overexpressed in tracheobronchial and pulmonary adenoid cystic carcinomas.
The expression levels of two target genes, Myb and VEGFR2 (show KDR Antibodies), were affected significantly by miR-16 (show GDE1 Antibodies), while glucose administration inhibited miR-16 (show GDE1 Antibodies) expression and enhanced tumor cell proliferation and migration.
All five successfully hybridized ACCs (show ACCS Antibodies) featured MYB rearrangement, whereas PLGAs did not show MYB rearrangement. Interestingly, one case of PLGA demonstrated a single intact copy of MYB in greater than 88% of the neoplastic cells. All ACCs (show ACCS Antibodies) exhibited consistent p63+/p40+ staining, whereas PLGAs demonstrated a p63+/p40- immunophenotype.
The MYB/MAF (show MAF Antibodies) co-silencing constrained the skewing of erythroid versus megakaryocyte lineage commitment in MYB-silenced CD34 (show CD34 Antibodies)+ cells, by restraining the expansion of megakaryocyte lineage while partially rescuing the impairment of erythropoiesis.
In summary, our results implicate that metastatic properties of some RMS subtypes might be linked to c-Myb function.
our study identifies super-enhancer translocations that drive MYB expression and provides insight into downstream MYB functions in alternate adenoid cystic carcinoma lineages.
MYB-QKI (show QKI Antibodies) rearrangements promote tumorigenesis through three mechanisms: MYB activation by truncation, enhancer translocation driving aberrant MYB-QKI (show QKI Antibodies) expression and hemizygous loss of the tumor suppressor QKI (show QKI Antibodies)
PIAS1 (show PIAS1 Antibodies) enhances p300 (show EP300 Antibodies) recruitment to c-Myb-bound sites through interaction with both proteins. In addition, the E3 activity of PIAS1 (show PIAS1 Antibodies) enhances further its coactivation
MYB is aberrantly overexpressed in PC cells and acts as a key determinant of pancreatic tumour growth and metastasis
Our data suggest that c-Myb is a transcription factor with multifaceted target regulation depending on cell type.
This gene encodes a transcription factor that is a member of the MYB family of transcription factor genes. The protein contains three domains, an N-terminal DNA-binding domain, a central transcriptional activation domain and a C-terminal domain involved in transcriptional repression. This protein plays an essential role in the regulation of hematopoiesis and may play a role in tumorigenesis. Alternative splicing results in multiple transcript variants.
, Avian myeloblastosis viral (v-myb) oncogene homolog
, v-myb myeloblastosis viral oncogene homolog (avian)
, transcriptional activator Myb-like
, gag-myb protein
, myb proto-oncogene protein
, myeloblastosis proto-oncogene product
, proto-oncogene c-Myb
, transcriptional activator Myb
, tumor-specific myb protein
, c-myb protein (140 AA)
, DNA-binding transcriptional regulator
, c-myb proto-oncogene