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VPS53 encodes a protein with sequence similarity to the yeast Vps53p protein. Additionally we are shipping VPS53 Proteins (3) and many more products for this protein.
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Human Polyclonal VPS53 Primary Antibody for ELISA, WB - ABIN1003473
Pérez-Victoria, Mardones, Bonifacino: Requirement of the human GARP complex for mannose 6-phosphate-receptor-dependent sorting of cathepsin D to lysosomes. in Molecular biology of the cell 2008
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Disruption of HCCS1 in mice leads to embryonic lethality, accompanied by abnormal labyrinth architecture resulting from the excessive proliferation of trophoblast cells in the placenta.
Golgi-associated retrograde protein orchestrates retrograde transport from endosomes to the trans-Golgi network by promoting vesicle tethering and assembly of SNARE (show NAPA Antibodies) complexes in consecutive, independent steps.[Golgi associated retrograde protein]
Golgi associated retrograde protein complex, consisting of the Vps52 (show VPS52 Antibodies), Vps53, and Vps54 (show VPS54 Antibodies) proteins, shows significant conservation between various species but diversification and specialization result in important differences in human cells.
Data show that transcription of the putative tumor suppressor gene HCCS1 requires binding of ETS-2 (show ETS2 Antibodies) to its consensus near the transcription start site; observations provide insight into the mechanistic aspects of HCCS1 transcription regulation
Amphipathic tail-anchoring peptide (ATAP) targets specifically to mitochondria, and induces caspase (show CASP3 Antibodies)-dependent apoptosis that does not require Bax (show BAX Antibodies) or Bak (show BAK1 Antibodies).
Missorting of cathepsin D (show CTSD Antibodies) in GARP (show CNGB1 Antibodies)-depleted cells results from accumulation of recycling MPRs in a population of light, small vesicles downstream of endosomes.
This gene encodes a protein with sequence similarity to the yeast Vps53p protein. Vps53p is involved in retrograde vesicle trafficking in late Golgi.
vacuolar protein sorting 53 homolog (S. cerevisiae)
, vacuolar protein sorting 53 homolog
, vacuolar protein sorting-associated protein 53 homolog
, vacuolar protein sorting 53