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Required for organelle biogenesis, protein secretion, and development. Additionally we are shipping VMP1 Antibodies (31) and VMP1 Kits (4) and many more products for this protein.
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Study indicated that the expression of VMP1 was down-regulated and negatively correlated to the prognosis of colorectal cancer.
In colorectal cancer cells, VMP1-dependent autophagy appears to be pro-survival rather than pro-cell death.
in patients with invasive ductal carcinoma of the breast, Vmp1 expression had significant influence on disease-free survival time, with Vmp1-negative patients showing poor prognosis
These results underscore a novel role for VMP1 as a potential therapeutic target for combinatorial therapies aimed at sensitizing pancreatic cancer cells to chemotherapeutic agents
The VMP1-Beclin 1 (show BECN1 Proteins) interaction regulates autophagy induction.
upregulation of Vmp1 was associated with suppression of growth and pulmonary metastases of HCC (show FAM126A Proteins).
AKT1 (show AKT1 Proteins)-GLI3 (show GLI3 Proteins)-VMP1 pathway mediates KRAS oncogene (show RAB1A Proteins)-induced autophagy in cancer cells.
The expression of VMP1 had significant negative influence on the survival rate of non-small-cell lung cancer patients.
VMP1 is reduced by hypoxia, and down-regulation of VMP1 by miR (show MLXIP Proteins)-210 mediates hypoxia-induced HCC (show FAM126A Proteins) cell metastasis.
A fusion transcript (RPS6KB1 (show RPS6KB1 Proteins)-VMP1) recurrently expressed in 30% of breast cancers is associated with clinical consequences and may indicate genomic instability altering the expression of oncogenic components such as MIR21 and RPS6KB1 (show RPS6KB1 Proteins).
Zymophagy, a novel selective autophagy pathway mediated by VMP1-USP9x-p62, prevents pancreatic cell death.
Required for organelle biogenesis, protein secretion, and development. Required for maintaining integrity of the endoplasmic reticulum. May play a role in autophagy.
transmembrane protein 49
, vacuole membrane protein 1
, transmembrane protein
, ectopic P-granules autophagy protein 3 homolog
, transport and golgi organization 5 homolog
, NF-E2 induceble protein-2
, NF-E2-inducible protein 2
, protein ni-2