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Vanin 2 Proteins (VNN2)

VNN2 product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. Additionally we are shipping VNN2 Antibodies (34) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
VNN2 8875 O95498
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Top VNN2 Proteins at

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 50 μg Log in to see 16 Days
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific pu... 1 mg Log in to see 29 to 34 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
HOST_Human Human His tag   10 μg Log in to see 5 Days

VNN2 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,

Top referenced VNN2 Proteins

  1. Human VNN2 Protein expressed in Human Cells - ABIN2004731 : Suzuki, Watanabe, Sakurai, Ohtake, Kinoshita, Araki, Fujita, Takei, Takeda, Sato, Yamashita, Araki, Sendo: A novel glycosylphosphatidyl inositol-anchored protein on human leukocytes: a possible role for regulation of neutrophil adherence and migration. in Journal of immunology (Baltimore, Md. : 1950) 1999 (PubMed)
    Show all 4 references for ABIN2004731

More Proteins for Vanin 2 (VNN2) Interaction Partners

Cow (Bovine) Vanin 2 (VNN2) interaction partners

  1. Ovulation is associated with an LH/hCG (show CGA Proteins)-forskolin-dependent up-regulation of VNN2 mRNA in bovine granulosa cells of preovulatory follicles via the adenyl cyclase (show ADCY1 Proteins)/cAMP pathway

Human Vanin 2 (VNN2) interaction partners

  1. GPI-80 defines a subpopulation of human fetal liver hematopoietic stem/progenitor cells (HSPCs) with self-renewal ability.

  2. DMSO induces neutrophil differentiation and provides suitable conditions for GPI-80 expression; this culture system is a model for the regulation of GPI-80 expression during myeloid differentiation.

  3. GPI-80 positive monocytes belong to a monocyte subpopulation that is superior in phagocytosis and reactive oxygen production, but inferior in antigen presentation

  4. elevated GPI-80 expression is associated with development and progression of thymoma

  5. some of the GPI-80 on pseudopodia of migrating neutrophils during the late phase was associated with urokinase-type plasminogen activator receptor (uPAR (show PLAUR Proteins)), a regulator of beta2 integrin-dependent adherence and migration

  6. analysis of structural divergence of GPI-80 in activated human neutrophils

VNN2 Protein Profile

Protein Summary

This gene product is a member of the Vanin family of proteins that share extensive sequence similarity with each other, and also with biotinidase. The family includes secreted and membrane-associated proteins, a few of which have been reported to participate in hematopoietic cell trafficking. No biotinidase activity has been demonstrated for any of the vanin proteins, however, they possess pantetheinase activity, which may play a role in oxidative-stress response. The encoded protein is a GPI-anchored cell surface molecule that plays a role in transendothelial migration of neutrophils. This gene lies in close proximity to, and in same transcriptional orientation as two other vanin genes on chromosome 6q23-q24. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Gene names and symbols associated with Vanin 2 Proteins (VNN2)

  • vanin 1 (VNN1)
  • vanin 2 (VNN2)
  • vanin 2 (LOC785817)
  • vanin 2 (LOC100345689)
  • FOAP-4 protein
  • GPI-80 protein
  • VNN2 protein
  • VNN3 protein

Protein level used designations for Vanin 2 Proteins (VNN2)

pantetheinase , vanin 2 , vanin 3 , vascular non-inflammatory molecule 2-like , Vannin 2 , glycosylphosphatidyl inositol-anchored protein GPI-80 , vanin-2 , vascular non-inflammatory molecule 2

421702 Gallus gallus
463006 Pan troglodytes
708637 Macaca mulatta
785817 Bos taurus
100067672 Equus caballus
100153984 Sus scrofa
100345689 Oryctolagus cuniculus
100436777 Pongo abelii
8875 Homo sapiens
534929 Bos taurus
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