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WW Domain Containing Transcription Regulator 1 Proteins (WWTR1)

WWTR1 encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. Additionally we are shipping WWTR1 Antibodies (44) and WWTR1 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
WWTR1 25937 Q9GZV5
Mouse WWTR1 WWTR1 97064 Q9EPK5
Rat WWTR1 WWTR1 295062  
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Top WWTR1 Proteins at antibodies-online.com

Showing 4 out of 5 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$388.93
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

WWTR1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,

More Proteins for WW Domain Containing Transcription Regulator 1 (WWTR1) Interaction Partners

Zebrafish WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. TAZ (show TAZ Proteins) has a critical role in osteoblast differentiation in vivo

Human WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. TAZ (show TAZ Proteins) may be involved in pancreatic tissue regeneration, and that deregulation of these proteins may play a role in neoplastic transformation and stellate cell functions in both PDAC and pancreatitis.

  2. we demonstrate additional structural complexity in WWTR1-CAMTA1 fusion transcripts in epithelioid haemangioendothelioma

  3. The study defines a YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins)-regulated transcriptional program in oral squamous cell carcinoma and reveals novel roles for nuclear YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins) activity in the onset and progression of this cancer.

  4. Human breast cancer database analysis revealed that increased expression (greater than the median) of both TAZ (show TAZ Proteins) and HIF-1 (show HIF1A Proteins) target genes, but neither one alone, is associated with significantly increased patient mortality.

  5. TAZ (show TAZ Proteins) negatively regulate transcription of DeltaNp63 through TEAD1,2,3 and 4 transcription factors.

  6. MicroRNA-9-3p was identified as the tumour-suppressor miR (show MLXIP Proteins) targetting TAZ (show TAZ Proteins) expression in hepatocellular carcinoma cells.

  7. miR (show MLXIP Proteins)-141 is a potent tumor suppressor in the stomach, and its growth inhibitory effects are, in part, mediated through its downstream target gene, TAZ (show TAZ Proteins).

  8. Report CAMTA1-WWTR1 gene fusion in thoracic epithelioid hemangioendothelioma but not epithelioid angiosarcoma.

  9. post-transcriptional regulation of Dicer (show DICER1 Proteins) is controlled by the cell density-mediated localization of the Hippo pathway effectors TAZ (transcriptional co-activator with PDZ-binding motif) and YAP (show YAP1 Proteins) (Yes-associated protein) (TAZ (show TAZ Proteins)/YAP (show YAP1 Proteins)).

  10. these results show that TAZ (show TAZ Proteins) mediates Wnt3a (show WNT3A Proteins)-stimulated osteogenic differentiation through PP1A (show PPP1CA Proteins), suggesting that the Wnt (show WNT2 Proteins) signal regulates the Hippo pathway.

Mouse (Murine) WW Domain Containing Transcription Regulator 1 (WWTR1) interaction partners

  1. Data show that low-power laser irradiation (LPLI (show LYPLA1 Proteins)) has an osteogenic potential by promoting osteoblast differentiation via TAZ (transcriptional co-activator with PDZ-binding motif) activation dependent on Akt (show AKT1 Proteins)/GSK3beta signaling pathway.

  2. These results suggest that YAP (show YAP1 Proteins) and TAZ (show TAZ Proteins) localization to the nucleus is required for skin wound healing.

  3. FGF2 (show FGF2 Proteins) induced TAZ (show TAZ Proteins) expression was stimulated by ERK (show EPHB2 Proteins) (extracellular signal-regulated kinase) activation.

  4. Knockdown of the Hippo mediators Yap1 (show YAP1 Proteins) or Taz (show TAZ Proteins) decreased in vitro cellular migration and transplantation of metastatic disease.

  5. ECG stimulates osteoblast differentiation through the activation of TAZ (show TAZ Proteins) and RUNX2 (show RUNX2 Proteins), revealing a novel mechanism for green tea-stimulated osteoblast differentiation

  6. Report comprehensive interactomes for TAZ (show TAZ Proteins).

  7. The Hippo signaling pathway and the effectors TAZ (show TAZ Proteins) and YAP (show YAP1 Proteins) regulated the differentiation of mesenchymal stem cells. [Review]

  8. SelW (show SEPW1 Proteins) enhances myoblast differentiation by inhibiting TAZ (show TAZ Proteins) binding to 14-3-3 (show YWHAQ Proteins).

  9. Study shows that in the absence of Wnt (show WNT2 Proteins), YAP (show YAP1 Proteins) and TAZ (show TAZ Proteins) are components of the destruction complex to which YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins) associate by binding to Axin1 (show AXIN1 Proteins); authors propose that the destruction complex serves as cytoplasmic anchor and functional sink for YAP (show YAP1 Proteins)/TAZ (show TAZ Proteins).

  10. TAZ (show TAZ Proteins) interacts with components of the SWI (show SMARCA1 Proteins)/SNF (show SNRPA Proteins) complex to modulate lineage-specific gene expression.

WWTR1 Protein Profile

Protein Summary

This gene encodes a binding protein of the 14-3-3 family of proteins that regulate cell cycle progression, differentiation and apoptosis. The encoded protein is a transcriptional co-activator that binds to the PPXY motif present on transcription factors. The gene product contains a WW domain and, in the C-terminus, a conserved PDZ-binding motif. This gene is distinct from the gene encoding tafazzin. Both genes share the gene symbol Taz. Multiple transcript variants encoding different isoforms have been described.

Gene names and symbols associated with WWTR1

  • WW domain containing transcription regulator 1 (wwtr1)
  • WW domain containing transcription regulator 1 (WWTR1)
  • WW domain containing transcription regulator 1 (Wwtr1)
  • 2310058J06Rik protein
  • 2610021I22Rik protein
  • C78399 protein
  • Taz protein
  • WWTR1 protein

Protein level used designations for WWTR1

WW domain containing transcription regulator 1 , WW domain-containing transcription regulator protein 1 , taz , WW domain-containing transcription regulator protein 1-like , transcriptional co-activator with PDZ-binding motif , transcriptional coactivator with PDZ-binding motif , transcriptional coactivator with PDZ binding motif , transcriptional co-activator with PDZ-binding motif (TA)Z , transcriptional co-activator with PDZ-binding motif (TAZ)

GENE ID SPECIES
496155 Xenopus laevis
568008 Danio rerio
100050661 Equus caballus
100401831 Callithrix jacchus
100437619 Pongo abelii
100493170 Xenopus (Silurana) tropicalis
100522573 Sus scrofa
100592028 Nomascus leucogenys
25937 Homo sapiens
609743 Canis lupus familiaris
614786 Bos taurus
97064 Mus musculus
295062 Rattus norvegicus
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