anti-Zinc Finger Protein 278 (ZNF278) Antibodies

The protein encoded by ZNF278 contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Additionally we are shipping Zinc Finger Protein 278 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ZNF278 23598 Q9HBE1
ZNF278 56218  
ZNF278 305471  
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Top anti-Zinc Finger Protein 278 Antibodies at antibodies-online.com

Showing 10 out of 20 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PATZ1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>OVCAR-3 cell lysate Host: Rabbit <br /> Target Name: PATZ1 <br /> Sample Tissue: Human Fetal Muscle <br /> Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-PATZ1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>WB Suggested Anti-PATZ1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>HT1080 cell lysate WB Suggested Anti-PATZ1 <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: HT1080 cell lysate <br /> There is BioGPS gene expression data showing that PATZ1 is expressed in HT1080 100 μL Log in to see 2 to 3 Days
$289.00
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human gastric tissue labeled with Anti PATZ1 Polyclonal Antibody,Unconjugated (ABIN759836) at 1:200 followed by conjugation to the secondary antibody and DAB staining. Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-PATZ1 Polyclonal Antibody, Unconjugated (ABIN759836) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$295.90
Details
Bat Rabbit Un-conjugated WB 50 μg Log in to see 7 to 9 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB Western blot analysis of extracts of various cells, using PATZ1 antibody. 100 μL Log in to see 16 Days
$323.13
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), WB Immunohistochemistry-Paraffin: PATZ Antibody [NBP2-19708] - Immunohistochemical analysis of paraffin-embedded Breast ca, using antibody at 1:250 dilution. Immunocytochemistry/Immunofluorescence: PATZ Antibody [NBP2-19708] - Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using antibody at 1:500 dilution. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details

ZNF278 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , ,
,
,
Mouse (Murine)


Rat (Rattus)


More Antibodies against Zinc Finger Protein 278 Interaction Partners

Human Zinc Finger Protein 278 (ZNF278) interaction partners

  1. The derived allele of rs174557, which is the common variant in most populations, diminishes binding of PATZ1, a transcription factor conferring allele-specific downregulation of FADS1 (show FADS1 Antibodies).

  2. Loss of PATZ1 expression is associated with thyroid cancer progression.

  3. Results show that PATZ1 binds to p53 (show TP53 Antibodies) and inhibits p53 (show TP53 Antibodies)-dependent transcription activation.

  4. these results propose that Patz1 is important for ESC pluripotency.

  5. The data support a PATZ1 tumour-suppressive function based on its ability to enhance p53 (show TP53 Antibodies)-dependent transcription and apoptosis.

  6. PATZ1 may have an important role in the regulation of EC senescence through an ROS (show ROS1 Antibodies)-mediated p53 (show TP53 Antibodies)-dependent pathway and contribute to vascular diseases associated with aging.

  7. these results showed a potentially novel mechanism of cAMP signaling mediated through the interaction of RIalpha (show PRKAR1A Antibodies) with PATZ1.

  8. MAZR and MITF (show MITF Antibodies) synergistically transactivated the mMCP-6 (show TPSB2 Antibodies) gene. MAZR appeared to play important roles in the normal phenotypic expression of mast cells in association with MITF (show MITF Antibodies)

  9. The results show that ZNF278 promotes cell growth, and its knockdown suppresses cell proliferation. ZNF278 could be a potential proto-oncogene (show RAB1A Antibodies) in colorectal cancer.

  10. The short isoform of the Zinc finger Sarcoma Gene (ZSG) was isolated as a RNF4 (show RNF4 Antibodies) interacting protein.

Mouse (Murine) Zinc Finger Protein 278 (ZNF278) interaction partners

  1. endothelial PATZ1 thus potently inhibits endothelial function and angiogenesis via inhibition of FABP4 (show FABP4 Antibodies) expression, and abnormal induction of endothelial PATZ1 may contribute to multiple aspects of vascular dysfunction in diabetes

  2. Together, these results suggest a novel mechanism regulating endothelial PATZ1 expression based on the down-regulation of miR (show MLXIP Antibodies)-24 expression caused by hyperglycemia. Interfering with PATZ1 expression via miRNAs or miRNA mimics could potentially represent a new way to target endothelial PATZ1-dependent signaling of vascular dysfunction in diabetes.

  3. the repression of ThPOK (show ZBTB7B Antibodies) during CD8 (show CD8A Antibodies) lineage differentiation is mediated by the synergistic activity of the transcription factor MAZR and Runx/CBFbeta (show CBFB Antibodies) complexes.

  4. Results show that PATZ1 binds to p53 (show TP53 Antibodies) and inhibits p53 (show TP53 Antibodies)-dependent transcription activation.

  5. The data support a PATZ1 tumour-suppressive function based on its ability to enhance p53 (show TP53 Antibodies)-dependent transcription and apoptosis.

  6. analysis of embryos in which Patz1 was disrupted revealed the presence of severe defects in the CNS and in the cardiac outflow tract, which eventually lead to a pre-mature in utero death during late gestation or soon after birth

  7. PATZ1 may have an important role in the regulation of EC senescence through an ROS (show ROS1 Antibodies)-mediated p53 (show TP53 Antibodies)-dependent pathway and contribute to vascular diseases associated with aging.

  8. controls the CD4 (show CD4 Antibodies) versus CD8 (show CD8A Antibodies) lineage fate of double-positive thymocytes

  9. MAZR and MITF (show MITF Antibodies) synergistically transactivated the mMCP-6 (show TPSB2 Antibodies) gene. MAZR appeared to play important roles in the normal phenotypic expression of mast cells in association with MITF (show MITF Antibodies)

  10. results demonstrate epigenetic control of the Cd8 (show CD8A Antibodies) loci and identify MAZR as an important regulator of Cd8 (show CD8A Antibodies) expression

Zinc Finger Protein 278 (ZNF278) Antigen Profile

Protein Summary

The protein encoded by this gene contains an A-T hook DNA binding motif which usually binds to other DNA binding structures to play an important role in chromatin modeling and transcription regulation. Its Poz domain is thought to function as a site for protein-protein interaction and is required for transcriptional repression, and the zinc-fingers comprise the DNA binding domain. Since the encoded protein has typical features of a transcription factor, it is postulated to be a repressor of gene expression. In small round cell sarcoma, this gene is fused to EWS by a small inversion of 22q, then the hybrid is thought to be translocated t1\;22p36.1\;q12. The rearrangement of chromosome 22 involves intron 8 of EWS and exon 1 of this gene creating a chimeric sequence containing the transactivation domain of EWS fused to zinc finger domain of this protein. This is a distinct example of an intra-chromosomal rearrangement of chromosome 22. Four alternatively spliced transcript variants are described for this gene.

Gene names and symbols associated with ZNF278

  • POZ (BTB) and AT hook containing zinc finger 1 (PATZ1) antibody
  • POZ (BTB) and AT hook containing zinc finger 1 (patz1) antibody
  • POZ (BTB) and AT hook containing zinc finger 1 (Patz1) antibody
  • 8430401L15Rik antibody
  • AI447519 antibody
  • dJ400N23 antibody
  • Mazr antibody
  • Patz antibody
  • RIAZ antibody
  • ZBTB19 antibody
  • Zfp278 antibody
  • Znf278 antibody
  • ZSG antibody

Protein level used designations for ZNF278

zinc finger protein 278 , BTB-POZ domain zinc finger transcription factor , BTB/POZ domain zinc finger transcription factor , MAZ-related factor , POZ-, AT hook-, and zinc finger-containing protein 1 , POZ-AT hook-zinc finger protein , protein kinase A RI subunit alpha-associated protein , zinc finger and BTB domain-containing protein 19 , zinc finger sarcoma gene protein , POZ and AT hook containing zinc finger 1 long C isoform , transcription factor (MAZ-related) MAZR

GENE ID SPECIES
100058375 Equus caballus
733194 Xenopus laevis
416963 Gallus gallus
23598 Homo sapiens
486365 Canis lupus familiaris
100328729 Oryctolagus cuniculus
56218 Mus musculus
305471 Rattus norvegicus
532416 Bos taurus
100153931 Sus scrofa
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