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May be involved in transcriptional regulation.. Additionally we are shipping and many more products for this protein.
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The authors show that ZNF451 is SUMO2 specific and that SUMO modification of ZNF451 may contribute to activity by providing a second molecule of SUMO that interacts with E2.
ZNF451 acts as a transcriptional corepressor for Smad3 (show SMAD3 Antibodies)/4 and negatively regulates TGF-beta (show TGFB1 Antibodies) signaling.
Data describe ZNF451, a nuclear protein (show RDBP Antibodies) that can be associated with promyelocytic leukemia (show PML Antibodies) bodies, and exerts its effects via SUMO modification machinery and trafficking of transcription regulators between promyelocytic leukemia (show PML Antibodies) bodies and nucleoplasm.
May be involved in transcriptional regulation.
coactivator for steroid receptors