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ZNRD1 encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Additionally we are shipping Zinc Ribbon Domain Containing 1 Antibodies (18) and Zinc Ribbon Domain Containing 1 Kits (10) and many more products for this protein.
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ZNRD1 regulatory SNPs may be susceptibility makers for risk of both chronic HBV infection and HCC (show FAM126A Proteins).
This study provides novel evidence that ZNRD1 polymorphism may confer host resistance to HIV-1 acquisition.
A miR (show MLXIP Proteins)-508-5p/ZNRD1/ABCB1 (show ABCB1 Proteins) regulatory loop has a critical role in MDR in gastric cancer.
Variants in ZNRD1 gene predict HIV-1/AIDS disease progression in a Han Chinese population in Taiwan.
Nominal associations were found between ZNRD1 rs1150740 and risk of AERD via codominant and dominant genetic inheritance (P=.03; odds ratio, 1.14 [1.14-10.16]).
The results of human miRNA array and real-time PCR showed that ZNRD1 could significantly up-regulate the expression of miR (show MLXIP Proteins)-214 and down-regulate the expression of miR (show MLXIP Proteins)-296.
siRNA-based functional analysis showed that ZNRD1 down-regulation by siRNA or shRNA impaired HIV-1 replication at the transcription level in both lymphoid and nonlymphoid cells.
ZNRD1 gene displays high expression in VCR resistant gastric cancer cells.
overexpression of ZNRD1 could promote multidrug-resistant phenotype of gastric cancer cells through upregulation of P-glycoprotein
This study clearly demonstrates that ZNRD1 may play an important role in the control of human gastric cancer development by regulating cell proliferation.
This gene encodes a protein with similarity to the Saccharomyces cerevisiae Rpa12p subunit of RNA polymerase I. Alternate splicing of this gene results in two transcript variants encoding the same protein. Additional splice variants have been described, but their full-length sequences have not been determined.
zinc ribbon domain containing 1
, DNA-directed RNA polymerase I subunit RPA12
, transcription-associated zinc ribbon protein
, nuclear RNA polymerase I small specific subunit Rpa12 like
, zinc ribbon domain-containing protein 1
, RNA polymerase I small specific subunit Rpa12
, nuclear RNA polymerase I small specific subunit