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ZNRF1 encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Additionally we are shipping ZNRF1 Antibodies (55) and many more products for this protein.
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up-regulation of ZNRF1 activity by oxidative stress leads to neuronal apoptosis and Wallerian degeneration.
The ZNRF1-AKT (show AKT1 Proteins)-GSK3B-CRMP2 (show DPYSL2 Proteins) pathway plays an important role in controlling Wallerian degeneration.
rs17684886 (ZNRF1) and rs599019 (COLEC12 (show COLEC12 Proteins)) are associated with diabetic retinopathy and rs6427247 (SCYL1BP1 (show GORAB Proteins)) and rs899036 (API5 (show API5 Proteins)) are associated with severe diabetic retinopathy in Chinese patients with type 2 diabetes
ZNRF1 and ZNRF2 (show ZNRF2 Proteins) are new players in regulation of the ubiquitous Na(+)/K(+)ATPase (show ATP1A1 Proteins) that is tuned to changing demands in many physiological contexts.
data suggest that ZNRF proteins play a role in the establishment and maintenance of neuronal transmission and plasticity via their ubiquitin ligase activity
These results suggest that ZNRF1 mediates regulation of neuritogenesis via interaction with tubulin (show TUBB Proteins).
This gene encodes an E3 ubiquitin-protein ligase that plays a role in neural-cell differentiation. Overexpression of this gene causes neurite-like elongation. The encoded protein contains both a zinc finger and a RING finger motif and is localized in the endosome/lysosome compartment, indicating that it may be involved in ubiquitin-mediated protein modification, and in synaptic vessicle membranes in neurons.
E3 ubiquitin-protein ligase znrf1
, zinc/RING finger protein 1
, E3 ubiquitin-protein ligase ZNRF1
, nerve injury-induced gene 283 protein
, peripheral nerve injury protein nin283
, ring finger protein 42
, zinc ring finger protein 1
, nerve injury gene 283
, zinc and ring finger protein 1