anti-anthrax Toxin Receptor 1 (ANTXR1) Antibodies

ANTXR1 encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. Additionally we are shipping anthrax Toxin Receptor 1 Proteins (14) and anthrax Toxin Receptor 1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ANTXR1 84168 Q9H6X2
ANTXR1 69538 Q9CZ52
ANTXR1 362393 Q0PMD2
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Top anti-anthrax Toxin Receptor 1 Antibodies at antibodies-online.com

Showing 10 out of 175 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ANTXR1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ANTXR1 Antibody (Y382)(ABIN392154) in Hela cell line lysates (35 µg/lane). ANTXR1 (arrow) was detected using the purified polyclonal antibody (1:60dilution). Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with ANTXR1 Antibody (Y382) (ABIN392154), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated DB Dot blot analysis of anti-Phospho-ANTXR1-pY425 Antibody (ABIN389986) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated DB Dot blot analysis of anti-Phospho-ANTXR1-pY382 Antibody (ABIN389930) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Goat Un-conjugated ELISA, WB ABIN185280 staining (0.3 ug/ml) of Human PBMC lysate (RIPA buffer, 35 ug total protein per lane).  Primary incubated for 1 hour.  Detected by western blot using chemiluminescence. 100 μg Log in to see 6 to 7 Days
$326.89
Details
Human Mouse Un-conjugated ICC, IF, IHC (p), IHC, WB Western blot detection of TEM8 in TEM8 transfected cell lysate using ABIN252540 at 1 ug/ml. Immunohistochemistry-Paraffin: TEM8/ANTXR1 Antibody (200C1339(SB20)) [ABIN2525395] - Formalin-fixed paraffin-embedded section of human colon stained with TEM8 antibody at 2.5 ug/ml concentration using DAB chromogen detection method (10X magnification) 0.1 mg Log in to see 7 to 9 Days
$408.19
Details
Human Goat Un-conjugated WB   0.1 mg Log in to see 12 to 15 Days
$375.38
Details

ANTXR1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-anthrax Toxin Receptor 1 Antibodies

  1. Human Monoclonal ANTXR1 Primary Antibody for ICC, IF - ABIN252539 : Matsuda, Ohga, Hida, Muraki, Tsuchiya, Kurosu, Akino, Shih, Totsuka, Klagsbrun, Shindoh, Hida: Isolated tumor endothelial cells maintain specific character during long-term culture. in Biochemical and biophysical research communications 2010 (PubMed)
    Show all 4 references for 252539

  2. Human Polyclonal ANTXR1 Primary Antibody for EIA - ABIN358475 : Wei, Lu, Chaudry, Leppla, Cohen: The LDL receptor-related protein LRP6 mediates internalization and lethality of anthrax toxin. in Cell 2006 (PubMed)
    Show all 3 references for 358475

  3. Human Polyclonal ANTXR1 Primary Antibody for DB - ABIN389930 : Werner, Kowalczyk, Faundez: Anthrax toxin receptor 1/tumor endothelium marker 8 mediates cell spreading by coupling extracellular ligands to the actin cytoskeleton. in The Journal of biological chemistry 2006 (PubMed)
    Show all 3 references for 389930

  4. Human Polyclonal ANTXR1 Primary Antibody for DB - ABIN389986 : Abrami, Leppla, van der Goot: Receptor palmitoylation and ubiquitination regulate anthrax toxin endocytosis. in The Journal of cell biology 2006 (PubMed)
    Show all 3 references for 389986

  5. Human Polyclonal ANTXR1 Primary Antibody for IHC (p), WB - ABIN392154 : Rainey, Wigelsworth, Ryan, Scobie, Collier, Young: Receptor-specific requirements for anthrax toxin delivery into cells. in Proceedings of the National Academy of Sciences of the United States of America 2005 (PubMed)
    Show all 3 references for 392154

  6. Human Polyclonal ANTXR1 Primary Antibody for EIA - ABIN358529 : Bradley, Mogridge, Mourez, Collier, Young: Identification of the cellular receptor for anthrax toxin. in Nature 2001 (PubMed)
    Show all 3 references for 358529

  7. Human Polyclonal ANTXR1 Primary Antibody for ELISA, WB - ABIN185280 : Carson-Walter, Watkins, Nanda, Vogelstein, Kinzler, St Croix: Cell surface tumor endothelial markers are conserved in mice and humans. in Cancer research 2001 (PubMed)

  8. Cow (Bovine) Polyclonal ANTXR1 Primary Antibody for WB - ABIN2784026 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against anthrax Toxin Receptor 1 Interaction Partners

Human anthrax Toxin Receptor 1 (ANTXR1) interaction partners

  1. These studies identify ANTXR1, a class of receptor that is shared by a mammalian virus and a bacterial toxin, as the cellular receptor for Seneca Valley virus.

  2. Findings suggest that down-regulation of tumor endothelial marker 8 play an important role in the inhibition of tumorigenesis and development of osteosarcoma.

  3. TEM8 may be differentially expressed between wound types and loss of this molecule impacts HaCaT growth and migration, potentially implicating this molecule as a factor involved in successful progression of wound healing.

  4. In the absence of any N-linked glycans, TEM8 fails to fold correctly and is recognized by the ER quality control machinery.

  5. These studies expand the allelic spectrum in this rare condition and potentially provide insight into the role of ANTXR1 in the regulation of the extracellular matrix.

  6. ANTXR2 (show ANTXR2 Antibodies) is expressed by human uterine smooth muscle cell and appears important for normal human uterine smooth muscle cell viability, migration and contractility.

  7. High ANTXR1 accelerates breast tumor growth and lung metastasis.

  8. There is an attenuation of ANTXR1 expression post-infection which may be a protective mechanism that has evolved to prevent reinfection.

  9. Mutations affecting ANTXR1 function are responsible for GAPO syndrome's characteristic generalized defect in extracellular-matrix homeostasis.

  10. An acidic region in the cytosolic tail of ANTXR1 decreases actin association, sending a signal that prevents binding of ANTXR1 to the protective antigen and providing evidence that cytoskeletal dynamics regulate ANTXR1 function.

Mouse (Murine) anthrax Toxin Receptor 1 (ANTXR1) interaction partners

  1. Anthrax Toxin Protective Antigen Variants That Selectively Utilize either the CMG2 (show ANTXR2 Antibodies) or TEM8 Receptors for Cellular Uptake and Tumor Targeting.

  2. An essential physiologic role for Antxr1 in arteriogenesis and peripheral artery disease.

  3. Data demonstrate that TEM8 is an essential regulator of connective tissue homeostasis. it controls synthesis of major matrix components in both endothelial and fibroblastic cells and regulates signaling pathways and matrix degradation.

  4. These results strongly suggest that TEM8 is the only minor anthrax toxin receptor mediating direct lethality in vivo and that other proteins implicated as receptors do not play this role.

  5. This is the first demonstration that the ATR/TEM8 protein is highly expressed in epithelial cells, suggesting that the ATR/TEM8 expression pattern is highly relevant for understanding the pathogenesis of anthrax infection.

  6. The mRNA transcripts of both receptors, ANTXR1 and ANTXR2 (show ANTXR2 Antibodies) were detected in J774A.1 cells and mouse tissues suggesting that anthrax edema toxin and B. anthracis Sterne spore are involved in the ANTXR mRNA regulation in host cells.

  7. Data show that the lethality of anthrax toxin for mice is mostly mediated by CMG2 (show ANTXR2 Antibodies) and that TEM8 plays only a minor role.

  8. Host-derived TEM8 promotes the growth of certain tumors.

anthrax Toxin Receptor 1 (ANTXR1) Antigen Profile

Protein Summary

This gene encodes a type I transmembrane protein and is a tumor-specific endothelial marker that has been implicated in colorectal cancer. The encoded protein has been shown to also be a docking protein or receptor for Bacillus anthracis toxin, the causative agent of the disease, anthrax. The binding of the protective antigen (PA) component, of the tripartite anthrax toxin, to this receptor protein mediates delivery of toxin components to the cytosol of cells. Once inside the cell, the other two components of anthrax toxin, edema factor (EF) and lethal factor (LF) disrupt normal cellular processes. Three alternatively spliced variants that encode different protein isoforms have been described.

Gene names and symbols associated with ANTXR1

  • anthrax toxin receptor 1 (ANTXR1) antibody
  • anthrax toxin receptor 1 (LOC100357637) antibody
  • anthrax toxin receptor 1 (Antxr1) antibody
  • 2310008J16Rik antibody
  • 2810405N18Rik antibody
  • Antrx1 antibody
  • ANTXR1 antibody
  • ATR antibody
  • Tem8 antibody

Protein level used designations for ANTXR1

anthrax toxin receptor 1 , tumor endothelial marker 8 , anthrax toxin receptor 1-like , 2310008J16Rik , 2810405N18Rik

GENE ID SPECIES
470393 Pan troglodytes
612601 Canis lupus familiaris
100061334 Equus caballus
100357637 Oryctolagus cuniculus
100410030 Callithrix jacchus
100425392 Macaca mulatta
100513853 Sus scrofa
100598321 Nomascus leucogenys
84168 Homo sapiens
69538 Mus musculus
362393 Rattus norvegicus
616010 Bos taurus
428199 Gallus gallus
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