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delta-Like 1 Homolog (Drosophila) Proteins (DLK1)

DLK1 encodes a transmembrane protein containing six epidermal growth factor repeats. Additionally we are shipping DLK1 Antibodies (159) and DLK1 Kits (12) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
DLK1 8788 P80370
DLK1 13386 Q09163
Rat DLK1 DLK1 114587  
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Top DLK1 Proteins at

Showing 10 out of 27 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 Days
HOST_Human Mouse Fc Tag   10 μg Log in to see 5 to 8 Days
HOST_Human Human Fc Tag   10 μg Log in to see 5 to 8 Days
HOST_Mammalian Cells Human His tag   50 μg Log in to see 5 Days
HOST_Human Human His tag   10 μg Log in to see 11 Days
HOST_Human Human DYKDDDDK Tag   10 μg Log in to see 5 to 8 Days
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
Yeast Human His tag   50 μg Log in to see 8 to 11 Days
HOST_Escherichia coli (E. coli) Human His tag   50 μg Log in to see 11 Days

DLK1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , ,
, , , ,
Mouse (Murine) ,
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More Proteins for delta-Like 1 Homolog (Drosophila) (DLK1) Interaction Partners

Cow (Bovine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. DLK1 mRNA expression in mesenteric fat was higher than subcutaneous fat. DLK1 mRNA expression in Holstein cattle mesenteric fat was higher than Wagyu cattle.

  2. The four loci of DLK1 gene and CLPG gene in 1109 individuals, which belong to eight breeds/species of bovidae, including cattle, buffalo and yak, were analyzed.

  3. tissue-specific expression patterns of Dlk-1 splice variants in bovine tissues

Human delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. NOTCH1 (show NOTCH1 Proteins) ligand Delta-like 1 (show DLL1 Proteins) homolog (DLK1) self interacts

  2. Pref-1 induces insulin (show INS Proteins) synthesis and secretion via two independent pathways

  3. Data from longitudinal, nested case-control study conducted in rural South Korea suggest that low serum levels of DLK1 (preadipocyte factor 1) may be useful biomarker for identifying women (but not men) at high risk of developing insulin (show INS Proteins) resistance, prediabetes, and type 2 diabetes.

  4. The appropriate timing of Dll1 (show DLL1 Proteins) expression is critical for its oscillatory expression, pointing to the functional significance of Dll1 (show DLL1 Proteins)-mediated oscillatory cell-cell interactions in the segmentation clock. [review]

  5. Results suggest a potential signalling hierarchy between Delta-like 1 (show DLL1 Proteins) and ephrin-B2 (show EFNB2 Proteins) ligands, as neural stem cells adopt the Delta-like 1 (show DLL1 Proteins) phenotype of stem cell maintenance on simultaneous presentation of both signals.

  6. The results indicate the occurrence of epimutation affecting the IG-DMR (show WDR20 Proteins) and the MEG3 (show FAM129B Proteins)-DMR (show WDR20 Proteins) in the two cases, and imply that UPD (show UROD Proteins)(14)mat and related (epi (show TFPI Proteins))genetic aberrations constitute a rare but important underlying factor for Silver-Russell Syndrome

  7. Kaplan-Meier analysis indicated that higher DLK1 levels were associated with shorter survival in Hepatocellular carcinoma (HCC (show FAM126A Proteins)) patients. These results suggest that the serum levels of DLK1 may serve as a prognostic biomarker for HCC (show FAM126A Proteins) patients.

  8. Notch (show NOTCH1 Proteins) pathway activation in endothelial colony forming cells in vivo via co-implanted stromal cells expressing delta-like 1 (show DLL1 Proteins) promotes vasculogenesis.

  9. Data show that the median expression of Jagged-1 (show JAG1 Proteins) protein and delta-like 1 (show DLL1 Proteins) protein (Dll-1 (show DLL1 Proteins)) was significantly higher in acute myeloid leukemia (show BCL11A Proteins) (AML (show RUNX1 Proteins)) blasts than in peripheral blood stem cells (PBSCs).

  10. DLK1 expression diminishes during differentiation of human U937 cel (show NOTCH1 Proteins)ls to macrophages.

Pig (Porcine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. We did not observe significantly different expression of DLK1, MEG3 or PEG11 mRNA in any of analyzed breeds.

  2. QUASEP supports paternal expression of DLK1 in whole brain, carcass, liver and placental tissues of day 30 interbreed porcine fetuses.

  3. the sequence of porcine DLK1 (pDLK1)was examined,the expression and alternative splicing isoforms in the pig (Sus scrofa) was compared with human

  4. Polymorphisms, imprinting status and quantitative trait locus analyses of the porcine DLK1 and MEG3 genes i swine.

  5. Expression of DLK1 splice variants during adipocyte development in vitro and in vivo.

Mouse (Murine) delta-Like 1 Homolog (Drosophila) (DLK1) interaction partners

  1. NOTCH1 (show NOTCH1 Proteins) ligand Delta-like 1 (show DLL1 Proteins) homolog (DLK1) self interacts

  2. the salivary gland phenotype of Dlk1 knock-out mice, was investigated.

  3. The brain-specific (show CALY Proteins) miR (show MLXIP Proteins)-379/miR (show MLXIP Proteins)-410 gene cluster at the imprinted Dlk1-Dio3 (show DIO3 Proteins) domain is implicated in several aspects of brain development and function.

  4. data provide the first evidence for a direct interaction between DLK1 and NOTCH1 (show NOTCH1 Proteins) in mammals, and substantiate that non-canonical NOTCH (show NOTCH1 Proteins) ligands exist, adding to the complexity of NOTCH (show NOTCH1 Proteins) signaling.

  5. the Dlk1-Gtl2 locus plays a critical role in preserving long-term repopulating HSCs (LT-HSCs).

  6. DNA methylation (show HELLS Proteins) regulates genomic imprinted DLK1-Dio3 (show DIO3 Proteins) miRNAs in autoimmune lupus

  7. identify the molecular regulators involved in the recruitment of AFF3 to gDMRs and provide mechanistic insight into the requirement of AFF3 at an enhancer for the expression of an approximately 200-kb polycistronic transcript within the imprinted Dlk1-Dio3 (show DIO3 Proteins) locus

  8. Dppa3 (show DPPA3 Proteins) has a critical role in generation of fully reprogrammed iPS (show SLC27A4 Proteins) cells and maintenance of Dlk1-Dio3 (show DIO3 Proteins) imprinting

  9. results suggest that maternal expression of the imprinted miR (show MLXIP Proteins)-379/miR (show MLXIP Proteins)-544 cluster regulates paternal expression of the Dlk1 gene in mice

  10. Dll1 (show DLL1 Proteins) and Jag1 (show JAG1 Proteins), Notch (show NOTCH1 Proteins) ligands, function redundantly and are necessary to maintain the centroacinar cells as an environmental niche in the developing pancreas.

DLK1 Protein Profile

Protein Summary

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes\; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance\; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass.

Gene names and symbols associated with DLK1

  • delta-like 1 homolog (Drosophila) (DLK1)
  • delta-like 1 homolog (Drosophila) (Dlk1)
  • AW742678 protein
  • Delta1 protein
  • DLK protein
  • DLK-1 protein
  • DlkI protein
  • FA1 protein
  • Ly107 protein
  • Peg9 protein
  • pG2 protein
  • pref-1 protein
  • PREF1 protein
  • SCP1 protein
  • Zog protein

Protein level used designations for DLK1

delta-like homolog , preadipocyte factor-1 , protein delta homolog 1 , delta-like 1 homolog (Drosophila) , delta-like protein 1 , protein delta homolog 1-like , fetal antigen 1 , preadipocyte factor 1 , secredeltin , adipocyte differentiation inhibitor protein , stromal cell derived protein 1

281117 Bos taurus
423459 Gallus gallus
490860 Canis lupus familiaris
707595 Macaca mulatta
100054933 Equus caballus
100082485 Ornithorhynchus anatinus
100303692 Meleagris gallopavo
100449207 Pongo abelii
100598289 Nomascus leucogenys
8788 Homo sapiens
497066 Sus scrofa
13386 Mus musculus
114587 Rattus norvegicus
641301 Ovis aries
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