You are viewing an incomplete version of our website. Please click to reload the website as full version.

gamma-Glutamylcyclotransferase Proteins (GGCT)

The protein encoded by GGCT catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. Additionally we are shipping gamma-Glutamylcyclotransferase Antibodies (53) and gamma-Glutamylcyclotransferase Kits (4) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
GGCT 110175 Q9D7X8
Rat GGCT GGCT 362368  
GGCT 79017 O75223
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top gamma-Glutamylcyclotransferase Proteins at antibodies-online.com

Showing 9 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 7 to 8 Days
$319.00
Details
HOST_Escherichia coli (E. coli) Human His-SUMO Tag 50 μg Log in to see 21 to 26 Days
$341.00
Details
HOST_Escherichia coli (E. coli) Human His tag 10 μg Log in to see 16 Days
$250.80
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,449.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 3 to 4 Days
$364.64
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details
Human Un-conjugated   5 μg Log in to see 6 Days
$168.54
Details

GGCT Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

Top referenced gamma-Glutamylcyclotransferase Proteins

  1. Human GGCT Protein expressed in Escherichia coli (E. coli) - ABIN667336 : Masuda, Maeda, Watanabe, Sano, Aiuchi, Nakajo, Itabe, Nakaya: A novel 21-kDa cytochrome c-releasing factor is generated upon treatment of human leukemia U937 cells with geranylgeraniol. in Biochemical and biophysical research communications 2006 (PubMed)
    Show all 2 references for ABIN667336

More Proteins for gamma-Glutamylcyclotransferase (GGCT) Interaction Partners

Human gamma-Glutamylcyclotransferase (GGCT) interaction partners

  1. GGCT plays a critical role in glioma cell proliferation and may be a potential cancer therapeutic target.

  2. GGCT is promising as a diagnostic marker and a therapeutic target for various cancers. This review summarizes these interesting findings.

  3. G6PD (show G6PD Proteins), GGCT, IDH1 (show IDH1 Proteins), isocitrate dehydrogenase 2 (show IDH2 Proteins) (NADP+,mitochondrial) (IDH2 (show IDH2 Proteins)) and glutathione S-transferase pi 1(GSTP1 (show GSTP1 Proteins)), five of the critical components of GSH pathway, contribute to chemoresistance.

  4. GGCT plays a critical role in lung cancer cell proliferation.

  5. Transcriptional silencing of the C7orf24 gene in the non-malignant cells is elicited through heterochromatin formation in its promoter region.

  6. increased expression of GGCT was a common event among invasive esophageal squamous cell carcinoma tissues regardless of the depth of invasion. Lymph node metastasis and tumor differentiation correlated with GGCT expression

  7. C7orf24 has been recognized as a potent marker for bladder and breast cancers. Studies on the role of gamma-glutamylcyclotransferace may aid in the control of malignant transformation of these cancers.

  8. GGCT may be a biomarker of tumors in a limited range of organs.

  9. C7orf24 overexpression defines a subgroup of breast tumors with poor clinical outcome.

  10. CRF21 (show IFNAR1 Proteins) might play an important role in the induction of apoptosis by GGO in leukemia U937 cells.

gamma-Glutamylcyclotransferase (GGCT) Protein Profile

Protein Summary

The protein encoded by this gene catalyzes the formation of 5-oxoproline from gamma-glutamyl dipeptides, the penultimate step in glutathione catabolism, and may play a critical role in glutathione homeostasis. The encoded protein may also play a role in cell proliferation, and the expression of this gene is a potential marker for cancer. Pseudogenes of this gene are located on the long arm of chromosome 5 and the short arm of chromosomes 2 and 20. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene names and symbols associated with GGCT

  • gamma-glutamyl cyclotransferase b (ggctb)
  • gamma-glutamylcyclotransferase (GGCT)
  • gamma-glutamylcyclotransferase (ggct)
  • gamma-glutamyl cyclotransferase (ggct)
  • gamma-glutamyl cyclotransferase (Ggct)
  • A030007L17Rik protein
  • AA673177 protein
  • C7orf24 protein
  • CRF21 protein
  • fj35c05 protein
  • GCTG protein
  • GGC protein
  • ggct protein
  • Ggctl1 protein
  • RGD1304876 protein
  • RGD1562590 protein
  • wu:fj35b07 protein
  • wu:fj35c05 protein
  • zgc:56140 protein

Protein level used designations for GGCT

gamma-glutamylcyclotransferase , gamma-glutamyl cyclotransferase , gamma-glutamyl cyclotransferase-like 1 , cytochrome c-releasing factor 21 , gamma -glutamyl cyclotransferase

GENE ID SPECIES
406278 Danio rerio
463327 Pan troglodytes
611603 Canis lupus familiaris
613056 Xenopus (Silurana) tropicalis
695547 Macaca mulatta
100528263 Ictalurus punctatus
110175 Mus musculus
362368 Rattus norvegicus
79017 Homo sapiens
533374 Bos taurus
Selected quality suppliers for gamma-Glutamylcyclotransferase Proteins (GGCT)
Did you look for something else?