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anti-phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) Antibodies

Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Additionally we are shipping PIK3AP1 Proteins (7) and PIK3AP1 Kits (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PIK3AP1 118788 Q6ZUJ8
PIK3AP1 83490 Q9EQ32
PIK3AP1 294048  
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Top anti-PIK3AP1 Antibodies at antibodies-online.com

Showing 10 out of 88 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis in A549 cell line lysates (35ug/lane) using PIK3AP1  Antibody  (C-term). This demonstrates the PIK3AP1 antibody detected the PIK3AP1 protein (arrow). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB PIK3AP1 Antibody (C-term) (ABIN656788) western blot analysis in A549 cell line lysates (35 µg/lane). This demonstrates the PIK3AP1 antibody detected the PIK3AP1 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated FACS, IF, IHC (p), WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IF, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated IF, WB 100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Mouse Un-conjugated FACS, IF, IHC, WB Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-PIK3AP1 mouse monoclonal antibody. (ABIN2453463) Immunohistochemical staining of paraffin-embedded Human lymph node tissue using anti-PIK3AP1 mouse monoclonal antibody. (ABIN2453463) 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, IF, WB Anti-PIK3AP1 mouse monoclonal antibody (ABIN2453458) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PIK3AP1 (RC214125). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PIK3AP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PIK3AP1. 100 μL Log in to see 2 to 3 Days
$423.50
Details
Human Mouse Un-conjugated FACS, WB HEK293T cells transfected with either RC214125 overexpress plasmid (Red) or empty vector control plasmid (Blue) were immunostained by anti-PIK3AP1 antibody (ABIN2453460), and then analyzed by flow cytometry. HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PIK3AP1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PIK3AP1. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated FACS, WB 100 μL Log in to see 8 to 10 Days
$529.83
Details
Rat Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$418.00
Details

PIK3AP1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-PIK3AP1 Antibodies

  1. Human Polyclonal PIK3AP1 Primary Antibody for EIA, WB - ABIN954143 : Koutros, Schumacher, Hayes, Ma, Huang, Albanes, Canzian, Chanock, Crawford, Diver, Feigelson, Giovanucci, Haiman, Henderson, Hunter, Kaaks, Kolonel, Kraft, Le Marchand, Riboli, Siddiq, Stampfer, Stram, Thomas, Travis, Thun, Yeager, Berndt: Pooled analysis of phosphatidylinositol 3-kinase pathway variants and risk of prostate cancer. in Cancer research 2010 (PubMed)
    Show all 5 references for ABIN954143

More Antibodies against PIK3AP1 Interaction Partners

Human phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) interaction partners

  1. Abi-1 (show ABI1 Antibodies) promotes Abl (show ABL1 Antibodies)-mediated BCAP (show PHF11 Antibodies) phosphorylation and suggest that Abi-1 (show ABI1 Antibodies) in general coordinates kinase-substrate interactions

Mouse (Murine) phosphoinositide-3-Kinase Adaptor Protein 1 (PIK3AP1) interaction partners

  1. Nck (show NCK1 Antibodies)-mediated recruitment of BCAP to the BCR (show BCR Antibodies) regulates the PI(3 (show PI3 Antibodies))K-Akt (show AKT1 Antibodies) pathway in B cells.

  2. BCAP is an essential activator of the PI3K pathway downstream of TLR signaling.

  3. BCAP is a unique TIR domain-containing toll (show TLR4 Antibodies) like receptor (TLR) signaling adapter crucial for linking TLRs to PI3K activation and regulating the inflammatory response.

  4. As macrophages engage their pathogenic targets, innate immune receptors trigger increased expression of BCAP, which endows them with the capacity to withstand further challenges from ongoing cellular insults, such as endoplasmic reticulum stress.

  5. BCAP-(L) (but not BCAP-(S)) is a negative regulator of the TLR-mediated host defense system in macrophages.

  6. BCAP and CD19 have complementary roles in BCR-mediated phosphoinositide 3-kinase activation

  7. model in which blunting of BCAP-mediated activation signaling in developing NK cells promotes functionality, terminal maturation, and long-term survival

PIK3AP1 Antigen Profile

Protein Summary

Involved in the activation of phosphoinositide 3-kinase (PI3K) in B-cells and in natural killer (NK) cells. Couples B-cell antigen receptor (BCR) to PI3K activation by providing a docking site for the PI3K subunit PIK3R1, which contributes to B-cell development. Seems to have a complementary role with CD19 in PI3K activation (By similarity). May be involved in the survival of mature B-cells via activation of REL (By similarity).

Gene names and symbols associated with PIK3AP1

  • phosphoinositide-3-kinase adaptor protein 1 (PIK3AP1) antibody
  • phosphoinositide-3-kinase adaptor protein 1 (Pik3ap1) antibody
  • 1810044J04Rik antibody
  • BCAP antibody
  • RP11-34E5.3 antibody

Protein level used designations for PIK3AP1

B cell adaptor protein , B-cell adapter for phosphoinositide 3-kinase , B-cell phosphoinositide 3-kinase adapter protein 1 , phosphoinositide 3-kinase adapter protein 1 , B cell phosphoinositide 3-kinase adaptor

GENE ID SPECIES
118788 Homo sapiens
83490 Mus musculus
294048 Rattus norvegicus
608653 Canis lupus familiaris
374268 Gallus gallus
Selected quality suppliers for anti-PIK3AP1 (PIK3AP1) Antibodies
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