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anti-phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A) Antibodies

The protein encoded by PLA2G2A is a member of the phospholipase A2 family (PLA2). Additionally we are shipping PLA2G2A Proteins (16) and PLA2G2A Kits (14) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLA2G2A 5320 P14555
PLA2G2A 29692 P14423
PLA2G2A 18780 P31482
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Top anti-PLA2G2A Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated IHC (p), IP, WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details
Mouse Sheep Un-conjugated IHC, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Mouse Rabbit Un-conjugated IHC, WB 100 μL Log in to see 9 Days
$302.50
Details
Human Sheep Un-conjugated IP, ELISA, WB   100 μg Log in to see 8 to 10 Days
$969.83
Details
Rat Rabbit Biotin ELISA, WB   100 μg Log in to see 9 to 11 Days
$328.90
Details
Human Mouse Un-conjugated IHC (p), IP, WB 50 μg Log in to see 5 to 6 Days
$541.80
Details
Human Rabbit Un-conjugated WB Western blot analysis of A549 and HeLa cell, using PLA2G2A Polyclonal Antibody at dilution of 1:500 200 μL Log in to see 8 to 9 Days
$588.50
Details
Rat Rabbit Biotin ELISA, WB   100 μg Log in to see 8 to 10 Days
$683.83
Details
Rat Rabbit FITC WB   100 μg Log in to see 8 to 10 Days
$713.17
Details

PLA2G2A Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Mouse (Murine)
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More Antibodies against PLA2G2A Interaction Partners

Human phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A) interaction partners

  1. Overexpression of sPLA2-IIA does not alter MCP-1 (show CCL2 Antibodies) level at baseline, but could enhance the atherogenic effect of oxidized LDL in HASMCs, at least partly due to activation of Akt (show AKT1 Antibodies).

  2. These results suggest that the genetic ablation of iPLA2b increased iron uptake in the brain through the activation of IRP2 (show IREB2 Antibodies) and upregulation of DMT1 (show DMRT1 Antibodies), which may be associated with mitochondrial dysfunction.

  3. IL-22 (show IL22 Antibodies) induced at an early stage of L. monocytogenes infection enhances innate immunity against L. monocytogenes in the liver by stimulating hepatocytes to produce PLA2G2A

  4. PLA2G2A was detected in all samples of endometriomas, but not in normal endometrium, and immunohistochemistry showed PLA2G2A-specific staining in epithelial cells of endometrioma paraffin sections.

  5. Results indicate that secreted phospholipase A2 IIA (sPLA (show YWHAZ Antibodies)2-IIA) as an enzyme working in concert with (show ALOX12 Antibodies) platelet microparticles (MPs) 12-lipoxygenase (12-LO) to promote internalization.

  6. Secretory PLA2 IIa expression can predict the clinical outcome of lung adenocarcinoma patients.

  7. Co-expression of PLA2G2A and COX-2 (show COX2 Antibodies) significantly correlated with the depth of invasion (p=0.004)and with TNM (show ODZ1 Antibodies) stage (p=0.04) of esophageal squamous cell carcinoma

  8. sPLA2 are secreted from ciliated cells and appear to induce mucin (show SLC13A2 Antibodies) and cysLT secretion from goblet cells, strongly suggesting that airway goblet cells are proinflammatory effector cells.

  9. Studies indicate that the expression of secreted phospholipases A2 (sPLA2s), most notably the group IIA, III and X enzymes, is dysregulated in various malignant tissues.

  10. PLA2G2A levels increase in expectorations of cystic fibrosis patients in an age-dependent manner.

Mouse (Murine) phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A) interaction partners

  1. Progesterone-induced Acrosome Exocytosis Requires Sequential Involvement of Calcium-independent Phospholipase A2beta (iPLA2beta (show PLA2G6 Antibodies)) and Group X Secreted Phospholipase A2 (show YWHAZ Antibodies) (sPLA2).

  2. Data show that the coordinated action of phospholipase A2 (show YWHAZ Antibodies) IIA (sPLA2-IIA) and 12-lipoxygenase (12-LO (show ALOX15 Antibodies)) promotes inflammatory arthritis.

  3. Pla2g2a sequence varies between tumor resistant and sensitive mouse strains. Some of these variations in the promoter region affect Pla2g2a expression and nonsense-mediated RNA decay also contributes to reducing Pla2g2a mRNA in tumor-sensitive strains.

  4. hydrolysis of the mitochondrial membrane by sPLA2-IIA yields inflammatory mediators (ie, lysophospholipids, fatty acids, and mtDNA) that promote leukocyte activation

  5. Ionomycin causes susceptibility to phospholipase A2 while temperature-induced increases in membrane fluidity fail: possible involvement of actin fragmentation.

  6. two of these isoforms, sPLA2 IIA and sPLA2 IIF, localize to the upper stratum granulosum and increase in response to experimental barrier perturbation.

  7. Investigation into the role of phosphatidylserine in modifying the susceptibility of lymphocytes to secretory phospholipase A(2) using cells deficient in the expression of scramblase.

  8. Data show changes in cell morphology and upregulation of ERK1/2, iNOS and sPLA-IIA expression in astrocytes and microglia on exposure to lipopolysaccharides and cytokines.

  9. Treated mice exhibited upregulated sPLA2-IIa and cytokine gene transcription.

  10. sPLA(2) may play a role in the development of the histologic changes produced by gastroduodenal reflux in esophageal mucosa.

Guinea Pig phospholipase A2, Group IIA (Platelets, Synovial Fluid) (PLA2G2A) interaction partners

  1. PLA2G2A production is induced by Pseudomonas aeruginosa.

PLA2G2A Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

Gene names and symbols associated with PLA2G2A

  • phospholipase A2, group IIA (platelets, synovial fluid) (PLA2G2A) antibody
  • phospholipase A2, group IIA (platelets, synovial fluid) (Pla2g2a) antibody
  • EF antibody
  • Mom1 antibody
  • Pla2 antibody
  • PLA2B antibody
  • PLA2L antibody
  • PLA2S antibody
  • PLAS1 antibody
  • sPLA2 antibody
  • sPla2-IIA antibody

Protein level used designations for PLA2G2A

GIIC sPLA2 , NPS-PLA2 , group IIA phospholipase A2 , non-pancreatic secretory phospholipase A2 , phosphatidylcholine 2-acylhydrolase 2A , phospholipase A2, membrane associated , eted enzyme type IIA phospholipase A2 , platelet phospholipase A2 , enhancing factor , modifier of Min1 , non-pancreatic secreted type II phospholipase A2 , secretory group II phospholipase A2 , typeII phospholipase A2

GENE ID SPECIES
5320 Homo sapiens
29692 Rattus norvegicus
18780 Mus musculus
521383 Bos taurus
100135599 Cavia porcellus
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