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anti-phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6) Antibodies

The protein encoded by PLA2G6 is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. Additionally we are shipping PLA2G6 Kits (10) and PLA2G6 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PLA2G6 53357 P97819
PLA2G6 8398 O60733
PLA2G6 360426 P97570
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Top anti-PLA2G6 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Western blot analysis of PLA2G6 Antibody (Center) (ABIN653895) in HepG2 cell line lysates (35 µg/lane). PLA2G6 (arrow) was detected using the purified polyclonal antibody. PLA2G6 Antibody (Center) (ABIN653895) IHC analysis in formalin fixed and paraffin embedded testis carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IF, IHC (p), WB Flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram) using PLA2G6  Antibody , followed by FITC-conjugated goat-anti-rabbit secondary antibodies. Confocal immunofluorescent analysis with HepG2 cell using PLA2G6  Antibody , followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: U87-MG 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Cow Rabbit Un-conjugated IHC (p), WB 0.125 mL Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated EIA, IHC (fro), WB   0.2 mL Log in to see 6 to 8 Days
$533.50
Details
Human Mouse Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated IP, WB PLA2G6 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLA2G6 expression in mouse kidney. PLA2G6 MaxPab rabbit polyclonal antibody. Western Blot analysis of PLA2G6 expression in human kidney. 100 μL Log in to see 9 Days
$418.57
Details
Human Mouse Un-conjugated WB Western Blot analysis of PLA2G6 expression in transfected 293T cell line by PLA2G6 MaxPab polyclonal antibody.Lane 1: PLA2G6 transfected lysate(82.72 KDa).Lane 2: Non-transfected lysate. 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (38.21 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details

PLA2G6 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) ,


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Human ,
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Rat (Rattus) ,


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Top referenced anti-PLA2G6 Antibodies

  1. Human Polyclonal PLA2G6 Primary Antibody for FACS, IF - ABIN954164 : Ayilavarapu, Kantarci, Fredman, Turkoglu, Omori, Liu, Iwata, Yagi, Hasturk, Van Dyke: Diabetes-induced oxidative stress is mediated by Ca2+-independent phospholipase A2 in neutrophils. in Journal of immunology (Baltimore, Md. : 1950) 2010 (PubMed)
    Show all 3 references for ABIN954164

  2. Human Polyclonal PLA2G6 Primary Antibody for EIA, IHC (fro) - ABIN1108663 : Maury, Prévost, Simon, Redoules, Ceruti, Tarroux, Charveron, Chap: Identification of two secreted phospholipases A2 in human epidermis. in The Journal of investigative dermatology 2000 (PubMed)

More Antibodies against PLA2G6 Interaction Partners

Pig (Porcine) phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6) interaction partners

  1. The results indicate that PKC (show FYN Antibodies) could be the final target and an integrator molecule of different signaling pathways triggered by angiotensin II (Ang II), which could explain the sustained activation of Na(+)-ATPase (show DNAH8 Antibodies) by Ang II (show AGT Antibodies).

Mouse (Murine) phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6) interaction partners

  1. Results suggest that the degeneration of dopaminergic neurons occurs mainly in the distal region of axons in iPLA2beta-KO mice.

  2. This study showed that the absence of iPLA2beta activity does not influence myocardial inflammation, but iPLA2beta is essential for T. cruzi clearance.

  3. Results support the deleterious role of iPLA2beta in severe obesity associated NAFLD (show TSC2 Antibodies).

  4. Genetic or molecular impairment of PLA2g6-dependent Ca(2+) signalling is a trigger for autophagic dysfunction, progressive loss of dopamine (show CA2 Antibodies)rgic (DA) neurons in substantia nigra pars compacta and age-dependent L-DOPA-sensitive motor dysfunction.

  5. An inactivation of iPLA2beta exacerbated pathogenesis of experimental colitis by promoting intestinal epithelial cell apoptosis, inhibiting crypt cell regeneration, and causing damage to mucus barrier allowing an activation of innate immune response.

  6. diapocynin inhibited ROS (show ROS1 Antibodies) production, abolished iPLA2 activity and reduced Ca2 (show CA2 Antibodies)+ influx through stretch-activated and store-operated channels, two major pathways responsible for excessive Ca2 (show CA2 Antibodies)+ entry in dystrophic muscle

  7. Mice deficient in iPLA2Beta show evidence of neuroinflammation and motor dysfunction in later life.

  8. membrane potential sensitive activity is the iPLA2gamma (show PNPLA8 Antibodies)

  9. In this study we demonstrate for the first time that corticostriatal LTP (show SCP2 Antibodies) is dependant on iPLA2 signalling, which can be reversed with application of DHA.

  10. Enteropathy may result from acute autoimmune hepatitis in a susceptible host such as iPLA2beta deficiency.

Human phospholipase A2, Group VI (Cytosolic, Calcium-Independent) (PLA2G6) interaction partners

  1. This study demonstrated that elevated expression of alphaSyn/PalphaSyn in mitochondria appears to be the early response to PLA2G6-deficiency in neurons.

  2. Stimulation of adrenoreceptors causes increased iPLA2 expression via MAP kinase/ERK (show MAPK1 Antibodies) 1 (show MAPK3 Antibodies)/2.

  3. genetic association study in Quebec City population: Data suggest total plasma n-6 fatty acid phospholipid levels and C-reactive protein (show CRP Antibodies) are modulated by SNPs in PLA2G4A (show PLA2G4A Antibodies) and PLA2G6 alone or in combination with fish oil dietary supplementation.

  4. Mutations in PLA2G6 altered Golgi morphology, O-linked glycosylation and sialylation of protein in patients with neurodegeneration

  5. PLA2G6 mutations in Indian patients with infantile neuroaxonal dystrophy (show SPTBN4 Antibodies) and atypical late-onset neuroaxonal dystrophy (show SPTBN4 Antibodies)

  6. Results demonstrated no significant impact of PLA2G6 and PLA2G4C (show PLA2G4C Antibodies) gene polymorphisms on attenuated niacin skin flushing in schizophrenia patients.

  7. Analysis of the cells from idiopathic Parkinson's disease patients reveals a significant deficiency in store-operated PLA2g6-dependent Ca(2 (show CA2 Antibodies)+) signalling

  8. Mutations in PANK2 and CoASY lead, respectively, to PKAN and CoPAN forms of Neurodegeneration with brain iron accumulation . Mutations in PLA2G6 lead to PLAN. Mutations in C19orf12 lead to MPAN

  9. our findings demonstrate that loss of normal PLA2G6 gene activity leads to lipid peroxidation, mitochondrial dysfunction and subsequent mitochondrial membrane abnormalities.

  10. genetic association studies in a population of Han Chinese: Data suggest that SNPs in PLA2G6 (rs132984; rs2284060) are associated with type 2 diabetes and hypertriglyceridemia in the population studied. [Meta-Analysis included]

PLA2G6 Antigen Profile

Protein Summary

The protein encoded by this gene is an A2 phospholipase, a class of enzyme that catalyzes the release of fatty acids from phospholipids. The encoded protein may play a role in phospholipid remodelling, arachidonic acid release, leukotriene and prostaglandin synthesis, fas-mediated apoptosis, and transmembrane ion flux in glucose-stimulated B-cells. Several transcript variants encoding multiple isoforms have been described, but the full-length nature of only three of them have been determined to date.

Gene names and symbols associated with PLA2G6

  • phospholipase A2, group VI (cytosolic, calcium-independent) (pla2g6) antibody
  • phospholipase A2, group VI (cytosolic, calcium-independent) (PLA2G6) antibody
  • phospholipase A2, group 6 (cytosolic, calcium-independent) (pla2g6) antibody
  • phospholipase A2, group VI (Pla2g6) antibody
  • phospholipase A2, group VI (cytosolic, calcium-independent) (Pla2g6) antibody
  • BB112799 antibody
  • CaI-PLA2 antibody
  • GVI antibody
  • INAD1 antibody
  • iPLA(2)beta antibody
  • iPla2 antibody
  • IPLA2-VIA antibody
  • iPLA2beta antibody
  • MGC83523 antibody
  • NBIA2 antibody
  • NBIA2A antibody
  • NBIA2B antibody
  • PARK14 antibody
  • PLA2 antibody
  • PLA2G6 antibody
  • PNPLA9 antibody
  • wu:fc06g09 antibody
  • zgc:77476 antibody

Protein level used designations for PLA2G6

85 kDa calcium-independent phospholipase A2 , patatin-like phospholipase domain containing 9 , phospholipase A2, group 6 (cytosolic, calcium-independent) , phospholipase A2, group VI (cytosolic, calcium-independent) , 85 kDa calcium-independent phospholipase A2-like , 85/88 kDa calcium-independent phospholipase A2 , GVI PLA2 , caI-PLA2 , group VI phospholipase A2 , iPLA2-beta , intracellular membrane-associated calcium-independent phospholipase A2 beta , patatin-like phospholipase domain-containing protein 9 , calcium-independent phospholipase A2 , cytosolic, calcium-independent phospholipase A2 , neurodegeneration with brain iron accumulation 2

GENE ID SPECIES
406370 Danio rerio
418028 Gallus gallus
446689 Xenopus laevis
481256 Canis lupus familiaris
700184 Macaca mulatta
100055064 Equus caballus
100415535 Callithrix jacchus
100445065 Pongo abelii
100515081 Sus scrofa
100549498 Meleagris gallopavo
100605211 Nomascus leucogenys
53357 Mus musculus
8398 Homo sapiens
535381 Bos taurus
101103799 Ovis aries
360426 Rattus norvegicus
Selected quality suppliers for anti-PLA2G6 (PLA2G6) Antibodies
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