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PAICS encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. Additionally we are shipping PAICS Proteins (10) and many more products for this protein.
Showing 10 out of 70 products:
Human Polyclonal PAICS Primary Antibody for IHC, IHC (p) - ABIN4278342
Duval, Luhrs, Wilkinson, Baresova, Skopova, Kmoch, Vacano, Zikanova, Patterson: Genetic and metabolomic analysis of AdeD and AdeI mutants of de novo purine biosynthesis: cellular models of de novo purine biosynthesis deficiency disorders. in Molecular genetics and metabolism 2013
Show all 3 references for ABIN4278342
Human Polyclonal PAICS Primary Antibody for EIA, FACS - ABIN953978
Joslyn, Ravindranathan, Brush, Schuckit, White: Human variation in alcohol response is influenced by variation in neuronal signaling genes. in Alcoholism, clinical and experimental research 2010
Show all 3 references for ABIN953978
Human Polyclonal PAICS Primary Antibody for FACS, IHC (p) - ABIN656869
Sugiyama, Masuda, Shinoda, Nakamura, Tomita, Ishihama: Phosphopeptide enrichment by aliphatic hydroxy acid-modified metal oxide chromatography for nano-LC-MS/MS in proteomics applications. in Molecular & cellular proteomics : MCP 2007
Chicken Polyclonal PAICS Primary Antibody for WB - ABIN2782454
Beausoleil, Villén, Gerber, Rush, Gygi: A probability-based approach for high-throughput protein phosphorylation analysis and site localization. in Nature biotechnology 2006
Two recessive zebrafish mutations that affect de novo purine synthesis, gart (show GART Antibodies) and paics, were analyzed.
purine biosynthetic pathway enzymes PPAT and PAICS, as well as pyruvate kinase activity are increased in lung cancer
This gene encodes a bifunctional enzyme containing phosphoribosylaminoimidazole carboxylase activity in its N-terminal region and phosphoribosylaminoimidazole succinocarboxamide synthetase in its C-terminal region. It catalyzes steps 6 and 7 of purine biosynthesis. The gene is closely linked and divergently transcribed with a locus that encodes an enzyme in the same pathway, and transcription of the two genes is coordinately regulated. The human genome contains several pseudogenes of this gene. Multiple transcript variants encoding different isoforms have been found for this gene.
multifunctional protein ADE2
, phosphoribosylaminoimidazole carboxylase
, phosphoribosylaminoimidazolesuccinocarboxamide synthase
, AIR carboxylase domain
, AIR carboxylase
, SAICAR synthetase
, multifunctional protein ADE2H1
, phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole succinocarboxamide synthetase
, Multifunctional protein ADE2 [Includes: Phosphoribosylaminoimidazole-succinocarboxamide synthase