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rho GTPase Activating Protein 1 Proteins (ARHGAP1)

ARHGAP1 encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. Additionally we are shipping ARHGAP1 Antibodies (48) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Rat ARHGAP1 ARHGAP1 315530  
ARHGAP1 228359 Q5FWK3
ARHGAP1 392 Q07960
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Top ARHGAP1 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ARHGAP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human , ,
,

More Proteins for rho GTPase Activating Protein 1 (ARHGAP1) Interaction Partners

Mouse (Murine) rho GTPase Activating Protein 1 (ARHGAP1) interaction partners

  1. These results demonstrate a different requirement of Cdc42 (show CDC42 Proteins) activity in primary mouse embryo fibroblasts suggesting that Cdc42 (show CDC42 Proteins) plays cell-type-specific signaling roles.

Human rho GTPase Activating Protein 1 (ARHGAP1) interaction partners

  1. study shows that HMHA1 (show HMHA1 Proteins) acts as a RhoGAP to regulate GTPase (show RACGAP1 Proteins) activity, cytoskeletal remodeling and cell spreading, which are crucial functions in normal hematopoietic and cancer cells

  2. The interaction of RhoGap protein (show ARHGAP26 Proteins) stabilizes the tetrameric conformation of p53 (show TP53 Proteins) and enhances its DNA-binding activity, thereby inducing cell-cycle arrest and apoptosis.

  3. In PC3 (show PCSK1 Proteins) cells, ARHGAP21 presented GAP activity for RhoA (show RHOA Proteins) and RhoC (show RHOC Proteins) and induced changes in cell morphology. Moreover, its silencing altered the expression of genes involved in cell proliferation and cytoskeleton organization

  4. RhoGAP Stard13 (show STARD13 Proteins) temporally and spatially regulates Rho activity in the developing pancreas to ensure that morphogenesis and establishment of tissue architecture are coordinated with organ growth.

  5. Rho proteins and ROK (show GRK1 Proteins) play a pivotal role in this signaling cascade

  6. PA and Rap1 (show RABGEF1 Proteins) cooperatively regulate RA-RhoGAP activity for promoting neurite outgrowth.

  7. Mutation of three residues of CDC42GAP involved in specific interactions of CDC42GAP with switch domain residues of Cdc42 (show CDC42 Proteins), as well as individual mutations of each of these residues, yields GAPs that are defective in stimulating GTP (show AK3 Proteins) hydrolysis.

  8. phosphorylation of Y1214 on VEGFR2 (show KDR Proteins) is required to trigger the sequential activation of Cdc42 (show CDC42 Proteins) and SAPK2/p38 (show MAPK14 Proteins) and to drive the SAPK2/p38 (show MAPK14 Proteins)-mediated actin remodeling in stress fibers in endothelial cells exposed to VEGF (show VEGFA Proteins)

  9. lipopolysaccharide-induced activation of the Rho family GTPase Cdc42 (show CDC42 Proteins), and we show its activation in the human neutrophil to be mediated by a p38 mitogen-activated protein kinase (show MAPK14 Proteins)-dependent mechanism.

  10. CDC42GAP was identified as a counter-regulatory mediator for tubule formation.

ARHGAP1 Protein Profile

Protein Summary

This gene encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes. The encoded protein contains a SRC homology 3 domain and interacts with Bcl-2-associated protein family members.

Gene names and symbols associated with ARHGAP1

  • Rho GTPase activating protein 32 (Arhgap32)
  • Rho GTPase activating protein 1 (Arhgap1)
  • Rho GTPase activating protein 1 (ARHGAP1)
  • B230365D05Rik protein
  • C76222 protein
  • CDC42GAP protein
  • Grit protein
  • p50rhoGAP protein
  • RHOGAP protein
  • RHOGAP1 protein
  • Rics protein
  • RP23-12H6.2 protein

Protein level used designations for ARHGAP1

rho GTPase-activating protein 32 , rho GTPase-activating protein 1 , rho-type GTPase-activating protein 1 , CDC42 GTPase-activating protein , GTPase-activating protein rhoGAP , GTPase-activating protein rhoOGAP , GTPase-activating protein, Rho, 1 , rho-related small GTPase protein activator , Cdc42 GTPase-activating protein

GENE ID SPECIES
315530 Rattus norvegicus
228359 Mus musculus
392 Homo sapiens
311193 Rattus norvegicus
483631 Canis lupus familiaris
512817 Bos taurus
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