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rho GTPase Activating Protein 21 (ARHGAP21) ELISA Kits

ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005 [PubMed 15793564]).[supplied by OMIM, Mar 2008].. Additionally we are shipping ARHGAP21 Antibodies (6) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ARHGAP21 57584 Q5T5U3
ARHGAP21 71435 Q6DFV3
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Top ARHGAP21 ELISA Kits at antibodies-online.com

Showing 2 out of 3 products:

Catalog No. Reactivity Sensitivity Range Quantity Supplier Delivery Price Details
Human 15.6-1000 pg/mL 96 Tests Log in to see 11 to 13 Days
$875.60
Details
Mouse
96 Tests Log in to see 11 to 13 Days
$875.60
Details

More ELISA Kits for ARHGAP21 Interaction Partners

Human rho GTPase Activating Protein 21 (ARHGAP21) interaction partners

  1. Gly1121Ser variant in ARHGAP21 gene found to be shared by all MP individuals in arger branch of family with nearly complete penetrance. ARHGAP21 protein strengthens cell-cell adhesions; may be regulated by BMPs influencing mandibular growth.

  2. ARHGAP21 is a Rho-GAP (show ARHGAP36 ELISA Kits) involved in cell-cell junction remodeling that affects migration and EMT (show ITK ELISA Kits) through alpha-tubulin (show TUBA4A ELISA Kits) interaction and acetylation

  3. Co-immunoprecipitations and in vitro SUMOylation confirmed ARHGAP21 specific modification by SUMO2/3 and mapped the SUMOylation site to ARHGAP21 lysine K1443.

  4. silencing Cdc42 reduced influenza A virus replication, whereas silencing ARHGAP21 increased the virus replication.

  5. Disruption of the beta-arrestin 1/ARHGAP21 complex results in a more active ARHGAP21, leading to less efficient signaling via the angiotensin II type 1A receptor and, thereby, attenuation of stimulated stress fiber formation.

  6. ARHGAP10 gene is highly expressed in muscle and brain, which are highly differentiated tissues. It supports the hypothesis that ARHGAP10 is important for cell differentiation

  7. The ARHGAP10 protein is a novel Rho GTPase-activating protein (show STARD13 ELISA Kits) (Rho-GAP (show ARHGAP36 ELISA Kits)) that is recruited to Golgi membranes through binding to GTP (show AK3 ELISA Kits)-ARF1 (show ARF1 ELISA Kits).

  8. The crystal structure of the activated GTP-bound form of ARF1 in a complex with the Arf-binding domain (ArfBD) of ARHGAP21 at 2.1 A resolution, is presented.

  9. Data demonstrate that the RhoGTPase activating protein 21 (ARHGAP21) is expressed in the nuclear and perinuclear regions of several cell lines, and interacts with the C-terminal region of focal adhesion kinase.

ARHGAP21 Antigen Profile

Antigen Summary

ARHGAP21 functions preferentially as a GTPase-activating protein (GAP) for CDC42 (MIM 116952) and regulates the ARP2/3 complex (MIM 604221) and F-actin dynamics at the Golgi through control of CDC42 activity (Dubois et al., 2005

Gene names and symbols associated with ARHGAP21

  • Rho GTPase activating protein 21 (ARHGAP21) antibody
  • Rho GTPase activating protein 21 (Arhgap21) antibody
  • 5530401C11Rik antibody
  • AA416458 antibody
  • ARHGAP10 antibody

Protein level used designations for ARHGAP21

Rho-GTPase activating protein 10 , rho GTPase-activating protein 10 , rho GTPase-activating protein 21 , rho-type GTPase-activating protein 21

GENE ID SPECIES
57584 Homo sapiens
71435 Mus musculus
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