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anti-serine Peptidase Inhibitor, Kazal Type 5 (SPINK5) Antibodies

SPINK5 encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. Additionally we are shipping and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
Anti-Rat SPINK5 SPINK5 361319  
SPINK5 11005 Q9NQ38
SPINK5 72432  
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Top anti-SPINK5 Antibodies at antibodies-online.com

Showing 10 out of 47 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SPINK5 Antibody (N-term) in A2058 cell line lysates (35ug/lane). SPINK5 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of SPINK5 Antibody (N-term) (ABIN390855) in A2058 cell line lysates (35 µg/lane). SPINK5 (arrow) was detected using the purified polyclonal antibody. SPINK5 Antibody (N-term) (ABIN390855) IHC analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 2 to 3 Days
$302.50
Details
Human Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$385.00
Details
Mouse Rabbit Un-conjugated ICC, IHC (fro), IHC (p), ELISA, WB 100 μg Log in to see 9 to 11 Days
$396.00
Details
Human Rabbit Biotin ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated ELISA, WB   100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated IHC, WB   100 μL Log in to see 8 to 10 Days
$581.17
Details
Human Rabbit Biotin ELISA, WB   100 μg Log in to see 8 to 10 Days
$639.83
Details

SPINK5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,


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Mouse (Murine) ,


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Top referenced anti-SPINK5 Antibodies

  1. Human Polyclonal SPINK5 Primary Antibody for EIA, WB - ABIN453393 : Nin, Katoh, Kokura, Handa, Yoshikawa, Kishimoto: Dichotomous effect of ultraviolet B on the expression of corneodesmosomal enzymes in human epidermal keratinocytes. in Journal of dermatological science 2009 (PubMed)

More Antibodies against SPINK5 Interaction Partners

Human serine Peptidase Inhibitor, Kazal Type 5 (SPINK5) interaction partners

  1. This report discloses a prevalent SPINK5 founder mutation in Finland and illustrates Netherton syndrome phenotype variability

  2. New mutation leading to the full variety of typical features of the Netherton syndrome.

  3. The results suggest that SPINK5 and ADRB2 (show ADRB2 Antibodies) haplotypes might play a role in the susceptibility to childhood-onset asthma

  4. The effect of GATA3 on SPINK5 expression was indirect and GATA3 alone was insufficient for final differentiation of keratinocytes where full SPINK5 expression was observed.

  5. these results support epistasis between SPINK5 and TSLP (show TSLP Antibodies), which contributes to childhood asthma.

  6. Netherton syndrome is caused by mutations in SPINK5, which encodes the serine protease inhibitor LEKTI.

  7. Herein we report three patients with Netherton syndrome who had growth retardation associated with GH deficiency and responded well to GH therapy.

  8. mesotrypsin (show PRSS3 Antibodies) contributes to the desquamation process by activating KLKs and degrading the intrinsic KLKs' inhibitor LEKTI

  9. The E420K LEKTI variant alters LEKTI proteolytic activation and results in protease deregulation.

  10. major binding partners of LEKTI were found to be the antimicrobial peptide (show cAMP Antibodies) dermcidin (show DCD Antibodies) and the serine protease (show F2 Antibodies) cathepsin G (show CTSG Antibodies) and no kallikreins.

Mouse (Murine) serine Peptidase Inhibitor, Kazal Type 5 (SPINK5) interaction partners

  1. Spink5/Par2 (show F2RL1 Antibodies) double knockout (DKO) mice, at embryonic day 19.5, display a dramatic decrease in TSLP (show TSLP Antibodies) expression, although stratum corneum detachment persists, confirming the role of the KLK5-PAR2 (show F2RL1 Antibodies) cascade in TSLP (show TSLP Antibodies)-mediated early proallergic signaling

  2. Mouse Spink5/Lekti, like its human counterpart, is involved in the control of epithelial tissue homeostasis.

SPINK5 Antigen Profile

Protein Summary

This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The inhibitor may play a role in skin and hair morphogenesis and anti-inflammatory and/or antimicrobial protection of mucous epithelia. Mutations may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with SPINK5

  • serine peptidase inhibitor, Kazal type 5 (Spink5) antibody
  • serine peptidase inhibitor, Kazal type 5 (SPINK5) antibody
  • 2310065D10Rik antibody
  • AV238912 antibody
  • LEKT1 antibody
  • LEKTI antibody
  • LETK1 antibody
  • LETKI antibody
  • NETS antibody
  • NS antibody
  • VAKT1 antibody
  • VAKTI antibody

Protein level used designations for SPINK5

serine protease inhibitor, Kazal type 5 , lympho-epithelial Kazal-type-related inhibitor , lymphoepithelial Kazal-type-related inhibitor , serine protease inhibitor Kazal-type 5 , Netherton syndrome

GENE ID SPECIES
361319 Rattus norvegicus
11005 Homo sapiens
72432 Mus musculus
Selected quality suppliers for anti-SPINK5 (SPINK5) Antibodies
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