SPINK5 antibody

Catalog No. ABIN7270212

Product Details anti-SPINK5 Antibody

Target: SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This SPINK5 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: SPINK5 / LEKTI Rabbit mAb

Cross-Reactivity: Human, Mouse, Rat

Characteristics: Monoclonal Antibodies

Purification: Affinity purification

Immunogen: Recombinant protein of Human SPINK5 / LEKTI.

Isotype: IgG

Application Details

Application Notes: WB,1:500 - 1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Avoid freeze / thaw cycles.

Target Details for SPINK5

Target: SPINK5 (serine Peptidase Inhibitor, Kazal Type 5 (SPINK5))

Alternative Name: SPINK5 / LEKTI (SPINK5 Products)

Synonyms: LEKTI antibody, LETKI antibody, NETS antibody, NS antibody, VAKTI antibody, 2310065D10Rik antibody, AV238912 antibody, LEKT1 antibody, LETK1 antibody, VAKT1 antibody, serine peptidase inhibitor, Kazal type 5 antibody, Spink5 antibody, SPINK5 antibody

Background: This gene encodes a multidomain serine protease inhibitor that contains 15 potential inhibitory domains. The encoded preproprotein is proteolytically processed to generate multiple protein products, which may exhibit unique activities and specificities. These proteins may play a role in skin and hair morphogenesis, as well as anti-inflammatory and antimicrobial protection of mucous epithelia. Mutations in this gene may result in Netherton syndrome, a disorder characterized by ichthyosis, defective cornification, and atopy. This gene is present in a gene cluster on chromosome 5. Alternative splicing results in multiple transcript variants.,SPINK5,LEKTI,LETKI,NETS,NS,VAKTI,Cell Biology & Developmental Biology,Ubiquitin,Cardiovascular,Angiogenesis,SPINK5 / LEKTI

Molecular Weight: 104kDa/120kDa/124kDa

Gene ID: 11005

UniProt: Q9NQ38