serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins (SERPINA3)

The protein encoded by SERPINA3 is a plasma protease inhibitor and member of the serine protease inhibitor class. Additionally we are shipping serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Antibodies (316) and serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Kits (37) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
SERPINA3 5265 P01009
Rat SERPINA3 SERPINA3 24648 P17475
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Top serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins at antibodies-online.com

Showing 10 out of 42 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Human His tag 10 μg Log in to see 20 to 21 Days
$250.80
Details
HOST_HEK-293 Cells Human His tag Human Serpin A3, His Tag on SDS-PAGE under reducing (R) condition. The gel was stained overnight with Coomassie Blue. The purity of the protein is greater than 95%. 50 μg Log in to see 2 to 3 Days
$346.50
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 30 to 35 Days
$4,331.68
Details
HOST_HEK-293 Cells Human His tag 10 μg Log in to see 2 to 3 Days
$220.00
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 15 to 19 Days
$286.00
Details
HOST_Human Human Un-conjugated 100 μg Log in to see 2 to 3 Days
$85.00
Details
HOST_Escherichia coli (E. coli) Human His tag,GST tag 100 μg Log in to see 15 to 18 Days
$416.00
Details
HOST_Mammalian Cells Human His tag   50 μg Log in to see 4 Days
$522.50
Details
HOST_Human Human His tag   10 μg Log in to see 15 to 16 Days
$300.00
Details
HOST_Human Human Un-conjugated   1 mg Log in to see 6 to 7 Days
$338.80
Details

SERPINA3 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , , , ,
, ,

Top referenced serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 Proteins

  1. Human SERPINA3 Protein expressed in Human Cells - ABIN2002551 : Vila, Obach, Revilla, Oliva, Chamorro: Alpha(1)-antichymotrypsin gene polymorphism in patients with stroke. in Stroke; a journal of cerebral circulation 2000 (PubMed)
    Show all 5 references for 2002551

  2. Human SERPINA3 Protein expressed in HEK-293 Cells - ABIN2181746 : Rubin, Wang, Nickbarg, McLarney, Naidoo, Schoenberger, Johnson, Cooperman: Cloning, expression, purification, and biological activity of recombinant native and variant human alpha 1-antichymotrypsins. in The Journal of biological chemistry 1990 (PubMed)
    Show all 3 references for 2181746

  3. Human SERPINA3 Protein expressed in Escherichia coli (E. coli) - ABIN666908 : Tachikawa, Tsuda, Onoe, Ueno, Takagi, Shinohara: alpha-1-Antichymotrypsin gene A1252G variant (ACT Isehara-1) is associated with a lacunar type of ischemic cerebrovascular disease. in Journal of human genetics 2001 (PubMed)
    Show all 2 references for 666908

More Proteins for serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) Interaction Partners

Horse (Equine) serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) interaction partners

  1. Although circulating nucleosomes and elastase - alpha 1-antitrypsin (show SERPINA1 Proteins) complexes are at present the best characterized biomarkers for neutrophil extracellular traps formation and neutrophil activation, their lack of association with rs2288904 genotype does not exclude a role for SLC44A2 (show SLC44A2 Proteins) in neutrophil activation (and possibly NET formation) in Venous Thromboembolism.

Human serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) interaction partners

  1. high A1AT (show SERPINA1 Proteins) expression correlated with increased tumor stage, elevated p53 (show TP53 Proteins) staining and shorter overall survival in lung adenocarcinoma patients.

  2. These results clearly demonstrate that the association of malectin with ribophorin I is required to capture misfolded alpha1-antitrypsin and direct them to the degradation pathway.

  3. AAT (show SERPINA1A Proteins) heterozygous status in rheumatoid arthritis is strongly associated with positive anti-citrullinated peptide autoantibodies and may define a distinct subset of patients with increased disease severity.

  4. Report alpha-1 antitrypsin (show SERPINA1 Proteins) Pi*Z gene frequency and Pi*ZZ genotype numbers worldwide.

  5. SNP rs8004738 of SERPINA1 (show SERPINA1 Proteins) gene significantly interacted with smoking status and was associated with a higher risk for COPD (show ARCN1 Proteins) in the Chinese population.

  6. tissue specific expression and regulation of short transcripts of SERPINA1 (show SERPINA1 Proteins) gene and the presence of C-terminal peptides in supernatants from activated neutrophils

  7. SERPINA1 (show SERPINA1 Proteins) variants are associated with ANCA-associated vasculitis risk.

  8. Report incorporation of the Mmalton allele-specific genotyping assay in the diagnostic algorithm of alpha-1-antitrypsin (show SERPINA1 Proteins) deficiency.

  9. The expression and intracellular accumulation of mutated Z-alpha-1 antitrypsin (show SERPINA1 Proteins) (the most common mutation) compromises macrophage function and contributes to emphysema development. Macrophages from individuals with Z-AAT (show SERPINA1A Proteins) have more proteolytic activity on ECM (show MMRN1 Proteins) than normal. This abnormal activity is not abrogated by exogenous AAT (show SERPINA1A Proteins) and may be the result of cellular dysfunction induced by intracellular accumulation of Z-AAT (show SERPINA1A Proteins).

  10. hAAT inhibits DC activation and function, and it also attenuates autoimmunity and renal damage in the MRL/lpr (show FAS Proteins) lupus model

serpin Peptidase Inhibitor, Clade A (Alpha-1 Antiproteinase, Antitrypsin), Member 3 (SERPINA3) Protein Profile

Protein Summary

The protein encoded by this gene is a plasma protease inhibitor and member of the serine protease inhibitor class. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease.

Gene names and symbols associated with SERPINA3

  • alpha-1-antichymotrypsin 1 (SERPINA3-1)
  • alpha-1-antichymotrypsin 3 (SERPINA3-3)
  • alpha-1-antichymotrypsin 2 (SERPINA3-2)
  • alpha-1-antichymotrypsin (LOC574106)
  • alpha-1-antitrypsin (SPI2)
  • alpha-1-antitrypsin (LOC100328621)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (SERPINA1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 (Serpina1)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 (SERPINA3)
  • serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SERPINA5)
  • SH2B adaptor protein 2 (Sh2b2)
  • A1A protein
  • A1AT protein
  • AACT protein
  • AAT protein
  • ACT protein
  • alpha1AT protein
  • Aps protein
  • GIG25 protein
  • LOC574106 protein
  • Pi protein
  • PI1 protein
  • Pi2 protein
  • PRO2275 protein
  • SERPINA3-1 protein
  • SERPINA3-2 protein
  • SERPINA3-3 protein
  • Spi1 protein

Protein level used designations for SERPINA3

alpha-1-antichymotrypsin 1 , alpha-1-antichymotrypsin 3 , alpha-1-antichymotrypsin 2 , alpha-1-antichymotrypsin , alpha-1-antiproteinase 2 , alpha-1-antitrypsin 2 , alpha-1-proteinase inhibitor 2 , alpha-1 protease inhibitor , alpha-1-antiproteinase , alpha-1-antitrypsin , alpha-1-antitrypsin null , protease inhibitor 1 (anti-elastase), alpha-1-antitrypsin , serine (or cysteine) proteinase inhibitor, clade A, member 1 , serpin A1 , alpha-1-antitrypsin (protease inhibitor) , alpha-1-protease inhibitor , alpha-1-proteinase inhibitor , serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 , serine protease inhibitor alpha 1 , cell growth-inhibiting gene 24/25 protein , growth-inhibiting protein 24 , growth-inhibiting protein 25 , serine (or cysteine) proteinase inhibitor, clade A, member 3 , serpin A3 , ACT , alpha-1-antiproteinase S

GENE ID SPECIES
396684 Sus scrofa
396685 Sus scrofa
396686 Sus scrofa
574106 Macaca mulatta
100065158 Equus caballus
100328621 Oryctolagus cuniculus
5265 Homo sapiens
24648 Rattus norvegicus
397688 Sus scrofa
12 Homo sapiens
100173860 Pongo abelii
423435 Gallus gallus
100379265 Cavia porcellus
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