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anti-serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) Antibodies

The protein encoded by SERPINF1 is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. Additionally we are shipping serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Kits (65) and serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Proteins (60) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
SERPINF1 57104 Q96AD5
SERPINF1 20317 P97298
SERPINF1 287526  
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Top anti-serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 143 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, IHC (p), WB Western blot analysis: A549 cell lysate was resolved by SDS-PAGE, transferred to PVDF membrane and probed with anti-human PEDF antibody (1:1000). Protein was visualized using a goat anti-mouse secondary antibody conjugated to HRP and an ECL detection system. 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Cow Rabbit Un-conjugated IHC, WB WB Suggested Anti-SERPINF1  Antibody Titration: 0.2-1 µg/mL  Positive Control: Human Placenta 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of SERPINF1 antibody (Center) (ABIN391483) in K562 cell line lysates (35 µg/lane). SERPINF1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SERPINF1 Antibody (Center) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of SERPINF1 Antibody (N-term) (ABIN391482) in 293 cell line lysates (35 µg/lane). SERPINF1 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with SERPINF1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of SERPINF1 Antibody (N-term) in 293 cell line lysates (35ug/lane). SERPINF1 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Mouse Un-conjugated WB HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINF1 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINF1. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 7 to 8 Days
$374.00
Details
Human Rabbit Un-conjugated IHC (p), WB Human Skin (formalin-fixed, paraffin-embedded) stained with SERPINF1 antibody ABIN337231 at 4-8 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$676.50
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain tissue labeled Anti-PEGF Polyclonal Antibody, Unconjugated (ABIN672456) at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat eye, ciliary body labeled Anti-PEGF Polyclonal Antibody, Unconjugated (ABIN672456) at 1:200, followed by conjugation to the secondary antibody Goat Anti-Rabbit IgG, Cy3 conjugated used at 1:200 dilution for 40 minutes at 37°C. 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB Western blot With PEDF antibody. Figure A: Lane 1: 50 µg Jurkat cell lysate. Lane 2: 50 µg 3T3 cell Lysate. Lane 3: 50 µg Mouse muscle lysate. Land 4: 50 µg Rat kidney lysate. Figure B: Lane 1: 2 ng Human recombinant PEDF Lane 2: 10 ng Human recombinant PEDF 100 μg Log in to see 2 to 3 Days
$304.50
Details

SERPINF1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Antibodies

  1. Human Monoclonal SERPINF1 Primary Antibody for EIA, IHC (p) - ABIN121181 : Baba, Yonemitsu, Nakano, Onimaru, Miyazaki, Ikeda, Sumiyoshi, Ueda, Hasegawa, Yoshino, Maehara, Sueishi: Cytoplasmic expression and extracellular deposition of an antiangiogenic factor, pigment epithelium-derived factor, in human atherosclerotic plaques. in Arteriosclerosis, thrombosis, and vascular biology 2005 (PubMed)
    Show all 3 references for ABIN121181

  2. Human Polyclonal SERPINF1 Primary Antibody for EIA, WB - ABIN453368 : Bessho, Kondo, Honda, Kuno, Negi: Coding variant Met72Thr in the PEDF gene and risk of neovascular age-related macular degeneration and polypoidal choroidal vasculopathy. in Molecular vision 2009 (PubMed)
    Show all 3 references for ABIN453368

  3. Human Polyclonal SERPINF1 Primary Antibody for FACS, IHC (p) - ABIN391483 : Tombran-Tink, Pawar, Swaroop, Rodriguez, Chader: Localization of the gene for pigment epithelium-derived factor (PEDF) to chromosome 17p13.1 and expression in cultured human retinoblastoma cells. in Genomics 1994 (PubMed)

  4. Cow (Bovine) Polyclonal SERPINF1 Primary Antibody for IHC, WB - ABIN2792309 : Matsumoto, Ishikawa, Nishimura, Hamasaki, Nakao, Eguchi: Antiangiogenic property of pigment epithelium-derived factor in hepatocellular carcinoma. in Hepatology (Baltimore, Md.) 2004 (PubMed)

More Antibodies against serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 Interaction Partners

Horse (Equine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. data suggest that PEDF, via its potent antiangiogenic capabilities, may contribute to superior healing in wounds on the trunks of horses by protecting from excessive formation of vascular granulation tissue

Human serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. Study demonstrated the inhibitory effect of PEDF on insulin (show INS Antibodies)-dependent molecular mechanisms of glucose homeostasis, and suggests that PEDF could be a specific target in the management of metabolic disorders.

  2. Study discuss the anti-tumor activities of PEDF and focus on its dual role as an inhibitor (e.g., angiogenesis) and as an inducer of various vital biological processes that lead to the therapeutic effect via different mechanisms of action. [review]

  3. hCG-induced PEDF downregulation and VEGF upregulation are mediated by similar signaling cascades emphasizes the delicate regulation of ovarian angiogenesis.

  4. We showed that transplantation of pigment epithelial cells overexpressing PEDF can restore a permissive subretinal environment for RPE (show RPE Antibodies) and photoreceptor maintenance, while inhibiting choroidal blood vessel growth.

  5. plasma PEDF similar in type 2 diabetes mellitus and obese groups of children

  6. We conclude that under OGD (show FGFR1 Antibodies) condition, PEDF and 44mer reduce H9c2 cells apoptosis and inhibit OGD (show FGFR1 Antibodies)-induced oxidative stress via its receptor PEDF-R and the PPARgamma (show PPARG Antibodies) signaling pathway.

  7. Data indicate that a tumor suppressor mechanism by which G0/G1 switch gene 2 (show G0S2 Antibodies) product (G0S2 (show G0S2 Antibodies)) directly inhibits activity of a key intracellular adipose triglyceride lipase (ATGL (show PNPLA2 Antibodies)).

  8. Authors show that rat ATGL (show PNPLA2 Antibodies), coactivated by rat CGI-58 (show ABHD5 Antibodies), efficiently hydrolyzes triglycerides and retinyl ester.

  9. PNPLA2 (show PNPLA2 Antibodies) mutations were associated with an extended phenotype, including brain involvement in cases of neutral lipid-storage disease with myopathy.

  10. Thus PEDF could be involved in the establishment of the avascular nature of seminiferous tubules and after puberty androgens may further reinforce this feature.

Mouse (Murine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. Study demonstrated the inhibitory effect of PEDF on insulin (show INS Antibodies)-dependent molecular mechanisms of glucose homeostasis, and suggests that PEDF could be a specific target in the management of metabolic disorders.

  2. Alpha-2-Antiplasmin mediated myofibroblast formation and the development of renal fibrosis in unilateral ureteral obstruction via induction of TGF-beta (show TGFB1 Antibodies).

  3. PEDF inhibits retinal microvascular dysfunction induced by 12/15-lipoxygenase-derived eicosanoids in diabetic retinopathy.

  4. Data suggest that pigment epithelium-derived factor (PEDF) and adipose triglyceride lipase (ATGL (show PNPLA2 Antibodies)) may serve as therapeutic targets for managing vascular hyperpermeability in sepsis.

  5. describe alterations in the PEDF signaling pathway and subventricular zone stem cell self-renewal at a very young age, which could be involved in the premature senescence observed in the SAM (show TTN Antibodies)-P8 model

  6. The combination of rAAV-PEDF with hyperthermia has synergistic therapeutic effects on established solid tumors, with no side effects.

  7. PEDF mediates reduced vasculogenesis.

  8. The results demonstrated that PEDF can protect 661W cells against light-induced cell death and suggest that the binding of PEDF to cell surface PEDF-R triggers a prosurvival signaling pathway.

  9. data suggest that the PEDF expression makes significant contribution to modulation of the inflammatory and angiogenic phenotype of the lung endothelium

  10. PEDF suppresses IL-1beta (show IL1B Antibodies)-mediated JNK (show MAPK8 Antibodies) activation to improve hepatocyte insulin (show INS Antibodies) signaling

Pig (Porcine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. After cryotherapy of the sclera, pigment epithelium-derived factor levels increased 44.8% compared to untreated controlsand stayed at that level until day 14. It returned to baseline by day 21. (untreated).

  2. the inhibitory effect of PEDF appears to be mediated via the processing of VEGF-R2 by gamma-secretase

Cow (Bovine) serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) interaction partners

  1. PEDF inhibits key steps in the angiogenic response of retinal capillary endothelial cells, including cell proliferation and vascular tubule formation. Gene expression of PEDF is negatively regulated by glucose, insulin (via mTOR) and VEGF.

  2. Results suggest that leptin (show LEP Antibodies) might elicit angiogenesis through vascular endothelial growth factor induction as well as pigment epithelium-derived factor suppression in pericytes.

  3. PEDF promotes growth of pericytes through autocrine production of PDGFB.

  4. PEDF and VEGFR-1 (show FLT1 Antibodies) have roles in the negative regulation of angiogenesis

serpin Peptidase Inhibitor, Clade F (Alpha-2 Antiplasmin, Pigment Epithelium Derived Factor), Member 1 (SERPINF1) Antigen Profile

Protein Summary

The protein encoded by this gene is a member of the serpin family, although it does not display the serine protease inhibitory activity shown by many of the other serpin family members. The encoded protein is secreted and strongly inhibits angiogenesis. In addition, this protein is a neurotrophic factor involved in neuronal differentiation in retinoblastoma cells.

Gene names and symbols associated with SERPINF1

  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (serpinf1) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (SERPINF1) antibody
  • patatin-like phospholipase domain containing 2 (PNPLA2) antibody
  • serine (or cysteine) peptidase inhibitor, clade F, member 1 (Serpinf1) antibody
  • serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 (Serpinf1) antibody
  • 1110001C14Rik antibody
  • AI195227 antibody
  • ATGL antibody
  • Dmrs91 antibody
  • EPC-1 antibody
  • iPLA2zeta antibody
  • MGC82984 antibody
  • OI6 antibody
  • OI12 antibody
  • Pedf antibody
  • PEDF-R antibody
  • Pedfl antibody
  • Sdf3 antibody
  • SERPINF1 antibody
  • TTS-2.2 antibody
  • TTS2 antibody

Protein level used designations for SERPINF1

serine (or cysteine) proteinase inhibitor, clade F), member 1 , serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 , pigment epithelium derived factor , serine (or cysteine) proteinase inhibitor, clade F, member 1 , serine (or cysteine) proteinase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1 , pigment epithelium-derived factor , serpin peptidase inhibitor, clade F, member 1 , pigment epithelium-derived factor-like , IPLA2-zeta , TTS2.2 , adipose triglyceride lipase , calcium-independent phospholipase A2 , desnutrin , patatin-like phospholipase domain containing protein 2 , patatin-like phospholipase domain-containing protein 2 , transport-secretion protein 2.2 , triglyceride hydrolase , SDF-3 , alpha-2 antiplasmin , caspin , serpin F1 , serpin-F1 , stromal cell derived factor 3 , stromal cell-derived factor 3 , cell proliferation-inducing gene 35 protein , serine (or cysteine) peptidase inhibitor, clade F, member 1 , alpha-2 antiplasmin, pigment epithelium derived factor

GENE ID SPECIES
394686 Xenopus (Silurana) tropicalis
444412 Xenopus laevis
468137 Pan troglodytes
771608 Gallus gallus
100072415 Equus caballus
100403187 Callithrix jacchus
100457889 Pongo abelii
100482247 Ailuropoda melanoleuca
100580793 Nomascus leucogenys
57104 Homo sapiens
20317 Mus musculus
100216362 Cavia porcellus
5176 Homo sapiens
287526 Rattus norvegicus
780402 Sus scrofa
611276 Canis lupus familiaris
281386 Bos taurus
100192425 Ovis aries
417561 Gallus gallus
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