Browse our Indoleamine 2,3-Dioxygenase 1 Proteins (IDO1)

Full name:
Indoleamine 2,3-Dioxygenase 1 Proteins (IDO1)
On are 13 Indoleamine 2,3-Dioxygenase 1 (IDO1) Proteins from 6 different suppliers available. Additionally we are shipping Indoleamine 2,3-Dioxygenase 1 Antibodies (188) and Indoleamine 2,3-Dioxygenase 1 Kits (17) and many more products for this protein. A total of 229 Indoleamine 2,3-Dioxygenase 1 products are currently listed.
cd107b, Ido, IDO-1, IDO1, Indo
list all proteins Gene Name GeneID UniProt
IDO1 3620 P14902
IDO1 15930 P28776
IDO1 66029 Q9ERD9

Show all synonyms

Indoleamine 2,3-Dioxygenase 1 Proteins (IDO1) by Origin

Select your origin of interest

Top referenced Indoleamine 2,3-Dioxygenase 1 Proteins

  1. Human IDO1 Protein expressed in Escherichia coli (E. coli) - ABIN2004475 : Barnes, Stephenson, Tooze, Doody: Amino acid deprivation links BLIMP-1 to the immunomodulatory enzyme indoleamine 2,3-dioxygenase. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)

More Proteins for Indoleamine 2,3-Dioxygenase 1 Interaction Partners

Cow (Bovine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Differential expression of CD25 (show IL2RA Proteins) and IDO mRNA with high and low virulence bovine viral diarrhea virus might reflect temporal differences in transcription during the immune response elicited by these viral strains.

  2. IDO may be involved in downregulating immune responses to M. avium subsp. paratuberculosis and other virulent mycobacteria, which may be an example of the pathogen harnessing host immunoregulatory pathways to aid survival.

  3. INDO participates in IFN-gama-induced death of bovine luteal cells, through a mechanism that involves degradation of tryptophan, thereby reducing tryptophan concentrations to a point insufficient to meet luteal cells needs

Rhesus Monkey Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. SIV-infected macaques exhibiting progression to AIDS displayed greater expression of TGF-beta (show TGFB1 Proteins) and indoleamine 2,3 dioxygenase in CD8 (show CD8A Proteins)+ T cells from mesentric lymph nodes.

Human Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. This study demonstrated that IDO-1 was elevated in the Solid Component and Cyst Fluid of Human Adamantinomatous Craniopharyngioma.

  2. The Binding Mode of N-Hydroxyamidines to Indoleamine 2,3-Dioxygenase 1

  3. Together, these results suggest that RSV infection of MSCs alters their immune regulatory function by upregulating IFN-b and IDO, affecting immune cell proliferation, which may account for the lack of protective RSV immunity and for chronicity of RSV-associated lung diseases such as asthma and COPD (show ARCN1 Proteins).

  4. Thus, our study provides novel insights into the interaction between a small molecule inhibitor INCB14943 and IDO1 protein. The structural information will facilitate future IDO1 inhibitor design.

  5. The aim of the present study was to clarify the effect of IDO1induced macrophages on the growth of endometrial stromal cells in endometriosis. IDO1 educated-macrophages may facilitate the survival of retrograde endometrial tissues, and be involved in the pathogenesis of endometriosis.

  6. Our results identified FGL2 (show FGL2 Proteins), GAL (show GAL Proteins), SEMA4D (show SEMA4D Proteins), SEMA7A (show SEMA7A Proteins), and IDO1 as new candidate genes that could be involved in MSCs-mediated immunomodulation. FGL2 (show FGL2 Proteins), GAL (show GAL Proteins), SEMA4D (show SEMA4D Proteins), SEMA7A (show SEMA7A Proteins), and IDO1 genes appeared to be differentially transcribed in the different MSC (show MSC Proteins) populations. Moreover, these genes were not similarly modulated following MSCs-exposure to inflammatory signals

  7. IDO mediated conversion of FOXP3 (show FOXP3 Proteins) -T cells to Tregs predominantly occurs in children with inflammatory bowel disease.

  8. The study confirmed that high IDO expression in pancreatic adenocarcinoma was related to poor prognosis of patients. These findings provided evidence that IDO was involved in pancreatic adenocarcinoma progression and might serve as a relevant therapeutic target.

  9. ver-expression of CTLA4 (show CTLA4 Proteins) and IDO1 was significantly associated with biochemical recurrence. Our results provide clues on the mechanisms of tumor development and point to potential biomarkers for early detection and treatment for prostate cancer in young men.

  10. IDO1 mRNA expression in cervical cancer

Mouse (Murine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

  1. Lipopolysaccharide (LPS (show TLR4 Proteins)) stimulation increased the expression and activity of the immunoregulatory enzyme IDO1 in hepatic stellate cells (HSCs), and LPS (show TLR4 Proteins)/HSCs stimulated aryl hydrocarbon receptor (AhR (show AHR Proteins)) signaling in cocultured regulatory T cells.

  2. this study shows that the presence of IFN-alpha (show IFNA Proteins) at antigen sensitization activates an IDO1/TGF-beta (show TGFB1 Proteins)-dependent anti-inflammatory program that upon antigenic rechallenge prevents inflammation via plasmacytoid dendritic cells

  3. Across strains, networks depicted a predominance of genes under-expressed in microglia relative to macrophages that may be a precursor for the different response of both cell types to challenges. The detected transcriptome differences enhance the understanding of the role of IDO1 in the microglia transcriptome under unchallenged conditions.

  4. Data show that indoleamine 23-dioxygenase 1 (IDO-1) inhibitors 1-methyl-D-tryptophan was able to alleviate most of the behavioural changes resulting from unpredictable chronic mild stress (UCMS) exposure.

  5. IDO did not play a pivotal role in the suppression of allergic airway inflammation through adipose-derived stem cells, suggesting that it is not the major regulator responsible for suppressing allergic airway inflammation.

  6. These results indicate that Platelet-activating Factor -mediated endotoxin tolerance is initiated via IDO- and JAK (show JAK3 Proteins)/STAT (show STAT1 Proteins)-dependent expression of SOCS3 (show SOCS3 Proteins).

  7. Aortic Plasmacytoid dendritic cells expressed CCR9 (show CCR9 Proteins) and indoleamine 2,3-dioxygenase 1 (IDO-1), an enzyme involved in driving the generation of regulatory T cells (Tregs).

  8. Indoleamine-2,3-dioxygenase (IDO) production by Plasmacytoid dendritic cells (pDCs)is necessary to confer suppressive function to T-Cells, Regulatory (Tregs) in experimental autoimmune encephalomyelitis (EAE).

  9. our findings support the hypothesis elevated IDO activity in non-CNS due to virus infections causes pain hypersensitivity

  10. this study shows that IDO overexpression in dendritic cells attenuates acute allograft rejection

Pig (Porcine) Indoleamine 2,3-Dioxygenase 1 (IDO1) interaction partners

Indoleamine 2,3-Dioxygenase 1 (IDO1) Protein Profile

Protein Summary

This gene encodes indoleamine 2,3-dioxygenase (IDO) - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, L-tryptophan, 5-hydroxy-tryptophan, tryptamine, and serotonin. This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its peri-cellular catabolization of the essential amino acid tryptophan.

Alternative names and synonyms associated with Indoleamine 2,3-Dioxygenase 1 (IDO1)

  • indoleamine 2,3-dioxygenase 1 (IDO1)
  • indoleamine 2,3-dioxygenase 1 (ido1)
  • indoleamine 2,3-dioxygenase 1 (Ido1)
  • indoleamine 2,3-dioxygenase 1-like (LOC100050681)
  • cd107b protein
  • Ido protein
  • IDO-1 protein
  • IDO1 protein
  • Indo protein

Protein level used designations for IDO1

indoleamine-pyrrole 2,3 dioxygenase , indoleamine 2,3-dioxygenase 2 , proto-IDO , putative indoleamine 2,3-dioxygenase , indoleamine 2,3-dioxygenase 1 , indolamine 2,3 dioxygenase , indole 2,3-dioxygenase , indoleamine-pyrrole 2,3-dioxygenase , IDO-1 , indoleamine 23-dioxygenase

506281 Bos taurus
100037099 Xenopus laevis
100086385 Ornithorhynchus anatinus
448488 Xenopus (Silurana) tropicalis
464134 Pan troglodytes
571967 Danio rerio
574370 Macaca mulatta
100032999 Monodelphis domestica
100196903 Ovis aries
3620 Homo sapiens
15930 Mus musculus
66029 Rattus norvegicus
475574 Canis lupus familiaris
100519877 Sus scrofa
100050681 Equus caballus
Selected quality suppliers for Indoleamine 2,3-Dioxygenase 1 Proteins (IDO1)
Did you look for something else?